The homeobox gene (HOXA13) codes for a transcription factor protein that binds to AT-rich DNA sequences and controls expression of many important proteins during embryonic morphogenesis. We report complete NMR chemical shift assignments of the mouse HOXA13 DNA binding domain (A13DBD; BMRB no. 16252). PMID:19888690

...2011-01-01 2011-01-01 false Application for employment authorization. 274a.13 Section 274a...SECURITY IMMIGRATION REGULATIONS CONTROL OF EMPLOYMENT OF ALIENS Employment Authorization § 274a.13 Application...

LFM-A13 (alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide) has recently been identified as an inhibitor of Polo-like kinases (Plk). LFM-A13 does not inhibit other serine/threonine kinases including CDK, CHK, RAF, DAPK, IKK, IRAK, JNK, MAPK, PKC and SAPK. ...

Primary immunization of humans with smallpox vaccine (live vaccinia virus (VACV)) consistently elicits antibody responses to six VACV virion membrane proteins, including A13. However, whether anti-A13 antibody contributes to immune protection against orthopoxviruses was unknown. Here, we isolated a murine ...

Jun 16, 2011 � Title: Deer mouse predation on the biological control agent, Urophora spp., introduced to control spotted knapweed. Author: Pearson, D. E. ...

B lymphocyte chemokine receptors signal to downstream effectors by activating heterotrimeric G proteins. However, many of these effectors remain unknown and the known ones often have ill-defined roles in B cell trafficking. Here we report that pharmacological inhibitors of phosphoinositide 3-kinases (wortmannin, WMN), Bruton's tyrosine kinase (LFM-A13), ...

The head's mouse controls were placed on a second hand-held unit, which includes the liquid crystal display (LCD) screen, the cursor mouse controls, ...

... Accession Number : ADA412406. Title : Mouse Cursor Control System Using EMG. Descriptive Note : Conference paper. ...

Contents: Rodents and human welfare; Description and habits of domestic rats and mice; Recognizing rat and mouse signs; Control of rodent populations; Sanitation for rat and mouse control; Rodent killing; Ratproffing; Organization of community rat-control...

... loop' and fine tune point-of-gaze controlled cursor positions. ... of-gaze control, pure head position control, and standard mouse control of display ...

... mouse or touch displays may be necessary. Specifically we propose to investigate the use of brain waves (electroencephalogram- EEG) to control ...

An introduction to mouse genetics where the basics of probability and statistics are presented before you choose which mice to breed for multiple generations. Determine the genetics that control the fur and eye color of the offspring.

... expressions of mouse PS2 gene in the E2-treated glands were calculated in comparison to that from non- treated control gland from mouse 1 (first ...

Conazoles are fungicides used to control fungal growth in environmental settings and to treat humans with fungal infections. Mouse hepatotumorigenic conazoles display many of the same hepatic toxicologic responses as the mouse liver carcinogen phenobarbital (PB): constitutive and...

... and NEP were also found in the mouse cerebral cortex, used as a positive control of amplification of ... neprilysin (NEP) mRNA transcripts in cDNA from mouse cerebral cortex, uterus, granulosa cells, oocy...

Molecular modeling studies led to the identification of LFM-A13 (alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide) as a potent inhibitor of Polo-like kinase (Plk). LFM-A13 inhibited recombinant purified Plx1, the Xenopus homolog of Plk, in a concentration-dependent fashion, as measured by autophosphorylation and phosphorylation of a ...

Computer interface control is typically accomplished with an input ''device'' such as keyboard, mouse, trackball, etc. An input device translates a users input actions, such as mouse clicks and key presses, into appropriate computer commands. To control t...

Four adult sheep were each injected with one of the following antigens: Mouse L cell interferon, human leukocyte interferon, mouse L cell interferon control and human leukocyte interferon control. Interferon antigens consisted of chromatographically purif...

... A CANDIDATE INSECT REPELLENTS A13-39013a, A13-6605, A13-38303b US DEPARTMENT OF AGRICULTURE PROPRIETARY CHEMICALS ...

... Specifically, we compared the standard laptop keyboard and mouse to a configuration incorporating a game controller. ...

... mouse. Progression of tumorigenesis in this line of knockout mice will be compared to heterozygous and wild type controls. ...

... mouse. Progression of tumorigenesis in this line of knockout mice will be compared to heterozygous and wild type controls. ...

... mouse. Progression of tumorigenesis in this line of knockout mice will be compared to heterozygous and wild type controls. ...

... mouse. Progression of tumorigenesis in this line of knockout mice will be compared to heterozygous and wild type controls. ...

... for each treatment and was compared to the inverse ratio of the control (IVF + 1.5% DMSO) in the same experiment. ... ...

... stimulation, and 3) precursor control of ACh ... The mouse hemidiaphragm preparation has been used ... The natural agonist, ACh, provoked frequency ...

The erythropoiesis modeling performed in support of the Body Fluid and Blood Volume Regulation tasks

Continuing work in controlled testing uses a one cylinder Ajax DP-115 (a 13.25 in bore OE 16 in stroke, 360 rpm engine) to assess a sequential analysis and evaluation of a series of engine upgrades. As with most of the engines used in the natural gas indu...

Continuing work in controlled testing uses a one cylinder Ajax DP-115 (a 13.25 in bore OE 16 in stroke, 360 rpm engine) to assess a sequential analysis and evaluation of a series of engine upgrades. As with most of the engines used in the natural gas indu...

A genomic clone encoding the gene for the mouse M1 muscarinic acetylcholine receptor has been isolated, placed under the control of the zinc-inducible mouse metallothionein promoter, and transfected into mouse Y1 adrenal cells. The receptor concentration ...

Decades of studies on the laboratory mouse have led to the knowledge that certain mouse strains are prone to developing certain cancers, and treatment strategies can be tested on mouse models. Other mice have been genetically engineered to have pre-disposing mutations that can be triggered to evade normal cellular ...

This study assessed whether two people with profound multiple disabilities and minimal motor behavior would be able to control environmental stimulation using thumb poke ability with a mouse wheel and a newly developed mouse driver (i.e., a new mouse driver replacing standard mouse driver, and ...

... running wheel activity (RWA) in C57Bl6 mice. ... Male and female transgenic and control animals have ... activity in a light controlled environment using ...

... that are directly involved in controlling cell division ... as fold changes over wild-type control. ... 5, indicating that mammary-specific gene expression did ...

... Title : Mechanisms for Controlling Breast Cancer Growth and Skeletal Metastasis. ... of breast cancer cell growth in a nude mouse xenograft model. ...

... Title : Mechanisms for Controlling Breast Cancer Growth and Skeletal Metastasis. ... validity of our in vitro finding we developed a mouse model where ...

java.lang.Object extended by java.awt.event.MouseAdapter extended by gov.nasa. worldwind.examples.util.BalloonController ...

sewers, an aid to controlling water pollution, typifies the aerospace spi noff process. Thesewer Mouse. An American Digital Systems field ...

We describe a computer vision based mouse, which can control and command the cursor of a computer or a computerized system using a camera. In order to move the cursor on the computer screen the user simply moves the mouse shaped passive device placed on a surface within the viewing area of the camera. The video generated by the camera ...

This Final Design Report (FDR) presents a review of the definitive design of the Sludge Handling System (SHS), Spent Nuclear Fuel (SNF) Sub-project A. 13(b). The information presented in this document, and the Sludge Handling System Compliance Matrix (HNF 8767), demonstrates compliance with HNF-6579, Baseline Design Criteria for the Sludge Handling System. ...

Mouse input does not work with Flash content in Windows WebView. A good test case is loading YouTube and trying to use the video controls. ...

Our overall goal is to use the mouse to identify genetic elements controlling sleep. We will use the Clock mutant mouse because of finding that Clock mutants, in addition to their circadian abnormalities, sleep less than wild-type mice. Over the past year...

... W. Reik, and W. Dean. Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol 2002. ... Chaillet. cis-Acting signal for inheritance of imprinted DNA methylation patterns in the preimp...

Phenyldichloroarsine (PDA), a vesicating analog of lewisite, was applied in an ethanol carrier to human skin xenografts on nude mice and directly to the ungrafted nude mouse skin. Controls areas received ethanol. Under light microscopy, we observed the fo...

of the genetic background #12;Institute of Laboratory Animal Science, Medical School Hannover Wild population of an outbred stock In experiments treatment and control group are not identical Animals are not identicalGenetics and nomenclature of mouse and rat strains #12;Institute of Laboratory Animal Science, Medical

... kit/bcl-2 transgene. To ensure that potential homozygotes were true homozygotes, they were bred with control mice (�/�). The offspring ... a mouse was negative for the transgene. Potential homozygotes tha...

Ingestion of bovine red blood cells opsonized with immunoglobulin, by irradiated and control cultures of mouse peritoneal macrophages, was monitored at various times following exposure to 7.5-20 Gy of 60 Co. Radiation produced decreases in the percentage ...

... is an intronless gene (Fig. 1A). The promoter regions of somatic and testis-specific histone H1 variants contain many regulatory elements, including TATA-, CAAT-, ... ...

The alkaline phosphomonoesterase activity of several mouse tissues and serum has been investigated in uninfected controls and animals infected with Diplococcus pneumoniae. No significant change of enzymatic activity was found in kidney, lung, sternum, fem...

A dozen people who cannot speak and have very limited voluntary muscle control because of cerebral palsy or traumatic brain injury have tried using a new technology called the Camera Mouse to access the computer. Nine of the people were successful, in many cases being able to spell words or run commercial software or access the internet for the first time. ...

Large scale international activities for systematic conditional mouse mutagenesis, exploiting advances in the sophisticated manipulation of the mouse genome, has established the mouse as the premier organism for developing models of human disease and drug action. Conditional mutagenesis is critical for the elucidation of the gene ...

In an effort to improve the stability of labile lactone ring and water solubility of camptothecin, five novel spin-labeled camptothecin derivatives were synthesized in quantitative yield by a simple modification of the carbodiimide method using the combination of scandium triflate (Sc(OTf)(3)) and 4-dimethylaminopyridine (DMAP), and the in vitro pharmacokinetic determination of the lactones of ...

Genetic polymorphisms of enzymes involved in the metabolism of carcinogens are suggested to modify an individual's susceptibility to lung cancer. The purpose of this study was to investigate the relationship between Japanese lung cancer cases and variant alleles of cytochrome P450 (CYP) 2A6 (CYP2A6*4), CYP2A13 ...

Ethylene glycol alkyl ethers are frequently used in industry, and accidents due to them occur. Impaired hematopoietic function and genital injury in animal experiments have been reported. Of various alkyl radicals, those with a methyl radical strongly injure them. Ethylene glycol dimethyl ether (EGDME) was administered to pregnant mice on the 7th, 8th, 9th, and 10th days of pregnancy, which is the ...

BackgroundZinc (Zn) is an essential trace element and it is abundant in connective tissues, however biological roles of Zn and its transporters in those tissues and cells remain unknown.Methodology/Principal FindingsHere we report that mice deficient in Zn transporter Slc39a13/Zip13 show changes in bone, teeth and connective tissue reminiscent of the ...

The effect of chronic furosemide treatment on the structure of the secretory cells in the mouse pancreas was studied using electron microscopy. The number of the zymogen granules increased in the cytoplasm of acinar cells; they were more densely packed and had a less electron-dense appearance than the controls. Because these ultrastructural findings ...

Patterns of Cell Death in Mouse Anteroventral Cochlear Nucleus Neurons After Unilateral Cochlea-induced cell death in the mouse AVCN. AVCN neurons in mature bcl-2 knockout mice demonstrate susceptibility to removal of afferent input comparable to neonatal sensitivity of wild-type controls. These data suggest

All NCI Mouse Repository strains are cryopreserved and archived as frozen embryos. Quality control testing is performed at the NCI Mouse Repository to ensure viability and genetic integrity of the frozen material. One aliquot of each batch of embryos is thawed and live-born mice of the proper genotype are produced.

significantly and abruptly B10 km from the genetic centre of the hybrid zone on the Mus musculus musculus side of the house mouse, Mus musculus musculus and M. m. domesticus. The two house mouse subspecies interbreed in reproductive isolation between two subspecies of house mouse: Mus musculus musculus and Mus musculus domesticus

This study was carried out to investigate the effects of acorn (Quercus acutissima CARR.) on brain dementia in mouse. Murine dementia model was induced by scopolamin administration to abdominal cavity (30 mg/kg BW). Male ICR mouse (30 ' 2 g BW) were fed basic diet (control group), or experimental d...

We evaluated the nerve growth factor (NGF) contents in the submaxillary gland of the mdx mouse, a model for Duchenne muscular dystrophy (DMD), and found that the NGF and NGF mRNA contents in this organ, where extraordinarily high amounts of NGF are synthesized and stored independently of development or maintenance of the nervous system, were markedly elevated in the male mdx ...

Photoacoustic microscopy (PAM) has been used to obtain high-resolution, noninvasive images of the in vivo mouse brain. In this work, we exploit the high-depth and temporal resolutions of PAM to noninvasively image the blood-oxygenation dynamics of multiple cortex vessels in the mouse brain simultaneously in response to controlled ...

Balloon based system to conduct microgravity experiment was developed. This system consists of high altitude balloon, Microgravity Operation Unit for Scientific Experiment (MOUSE), and Balloon based Operation Vehicle (BOV). BOV drops from the balloon. But due to the residual air drag, BOV do not fall freely. So, MOUSE floats freely inside BOV body. BOV ...