21st Century Biomedicine
Considerable momentum has been building in government, academe, and the commercial sector towards implementation of a "rapid-learning health system." In this approach to biomedicine, research and clinical care are seamlessly linked in a way that enables the collection and analysis of clinical outcomes of large populations.
This knowledge can then be applied to drive discovery and clinical development of new products and treatments. The changes taking place behind this new approach are often referred to as "Health 2.0." Click here to learn more about Health 2.0.
Publications
Enabling Personalized Medicine through Health Information Technology
Center for Technology Innovation at Brookings – January 28, 2011
This report from the Center for Technology Innovation at Brookings outlines the challenges of enabling personalized medicine, and highlights caBIG® as a data model for overcoming these challenges by facilitating connectivity, integration, and the analysis of information.
Testimony on Opportunities for an IT-enabled Ecosystem to Transform Biomedicine
Remarks by Ken Buetow, Ph.D., to the Health IT Standards Committee – March 8, 2010
This testimony focuses on the opportunity for an IT-enabled ecosystem to transform biomedicine, and the pending launch of a Patient Outcomes Data Service that will collect, aggregate, analyze, and disseminate data in a new web-based resource called the Cancer Knowledge Cloud to fuel research and improve clinical care.
Actualizing 21st Century Biomedicine
BIG Health Consortium™ – August 2009
This article, by Ken Buetow, Ph.D., Associate Director for Bioinformatics and Information Technology, National Cancer Institute, describes a "rapid-learning health system," connected via electronic tools and infrastructure through which massive amounts of data can be aggregated and disseminated, paving the way to a new generation of personalized medicine.
The Case for Personalized Medicine
Personalized Medicine Coalition – May 2009
The 2009 edition of The Case sheds light on the demonstrated benefits of personalized medicine and describes the pathway for its widespread adoption to improve healthcare.
Personalized Heath Care: Pioneers, Partnerships, Progress (caBIG® Case Study)
Department of Health and Human Services – November 2008
This report describes how The Personalized Health Care Initiative will improve the safety, quality, and effectiveness of healthcare for every patient in the U.S. by using genomics to enable medicine to be tailored to each person's needs.
Personalized Heath Care: Pioneers, Partnerships, Progress (Full Report)
Department of Health and Human Services – November 2008
Secretary Leavitt and the Department of Health and Human Services released their 2008 Report on Personalized Medicine entitled, "Personalized Health Care: Pioneers, Partnerships, Progress."
Personalized Medicine—BIG Health
Cancer Bulletin – August 5, 2008
In the August issue of the National Cancer Institute's Cancer Bulletin, Dr. Ken Buetow provided a guest update in which he announces the BIG Health Consortium.
Presentations
Personalized Medicine and Digital Health Networks in Cancer Research and Clinical Care
AMIA Joint Summits on Translational Science – March 9, 2011
The Role of Patients and Consumers in New Models of Research: caBIG® and My Cancer e-LIFE
2010 caBIG® Annual Meeting – September 14, 2010
The BIG Idea: Strategies to Achieve a Rapid-Learning Health System
Bio IT World 2010 Conference and Expo – April 20-22, 2010
Testimony Presented by Ken Buetow as part of the Public Sector Panel
Health IT Standards Committee Meeting – March 8, 2010
caBIG® Innovation Platform: New Generation of Biomedicine
2009 caBIG® Annual Meeting – July 21, 2009
"Transforming the Research Paradigm: 21st Century Models to Unify Discovery Research and Clinical Care"
BIO International Convention – May 19, 2009
Linking Research and Care to Make Personalized Medicine a Reality: BIG Health Overview
BIG Health Consortium™ Webinar – December 15, 2008
Director's Notes
caBIG® and the ongoing transformation of biomedicine
caBIG® LINKS – September 2010
New opportunities for advancing cancer research
caBIG® LINKS – August 2010
Trends that promise to make 2010 a transformative year in biomedicine
caBIG® LINKS – January/February 2010
The journey of health information technology during the last decade
caBIG® LINKS – December 2009
The value in linking research and care
caBIG® LINKS – June 2009
Transforming the nation's health care with HIT
caBIG® LINKS – January 2009
Media Coverage
Kenneth Buetow and caBIG®
The Health Care Blog – July 17, 2010
At Health 2.0 Goes to Washington on June 7, 2010, Kenneth Buetow, Associate Director of BioInformatics for the National Cancer Institute and Founder of caBIG®, talked about the launching of a large scale effort called Cancer Biomedical Informatics Grid (caBIG®).
Chopra cites federal projects as health IT catalysts
Government Health IT – March 9, 2010
Government Health IT featured an article by Mary Mosquera, which quotes Dr. Ken Buetow and Aneesh Chopra. In the article, Chopra commented that caBIG® standards and terminology could be commercially adopted as a means of patient engagement and data exchange. Dr. Buetow added that the cancer registry service enables physicians to collect and share information about cancer diagnoses, treatment, and clinical outcomes of individual patients, as well as the outcomes of all of their patients in the aggregate.