The Biological Small-Angle Neutron Scattering Instrument at HFIR
Detector tanks for the SANS instruments at HFIR. The Bio-SANS detector is on the left.
Bio-SANS was designed and optimized for analysis of the structure, function, and dynamics of complex biological systems. Bio-SANS is the cornerstone of the Center for Structural Molecular Biology (CSMB) at Oak Ridge National Laboratory. The Bio-SANS instrument is supported by additional CSMB capabilities that include development of advanced computational tools for neutron analysis and modeling, as well as biophysical characterization and X-ray scattering infrastructure. A dedicated biological sample preparation laboratory is located adjacent to the instrument.
Bio-SANS user Brad O’Dell talks about using small-angle neutron scattering to study cyanobacteria.
Applications
Bio-macromolecules and their assemblies
- Protein complexes
- Protein/DNA complexes
- Lipids
- Viruses
- Carbohydrates
Hierarchical biological structures
- Gels
- Fibers and fibrils
- Vesicles
- Microemulsions
Membrane diffraction
Biomimetic and bio-inspired systems
Center Director
Instrument Scientists
Instrument Information
- Bio-SANS Home Page
- Instrument Team
- Specifications
- Research Highlights
- Research Publications
- Printable Fact Sheet
