United States Department of Veterans Affairs
R&D HOME » NEWS » RESEARCH_HIGHLIGHTS

Research Highlights

Study on Vietnam-era women veterans will be largest ever

September 11, 2009

Time/Life portrait of Nurse Hamilton, one of about 8,000 women who served with the U.S. military in Vietnam during the war there.

Lifesaver— Time/Life portrait of "Nurse Hamilton," one of about 8,000 women who served with the U.S. military in Vietnam during the war there. (Photo by John Olson).

Christmas, 1968. Army nurse Joan Furey, a curly-haired 22-year-old brunette, was visiting her folks on Long Island. She broke the news to them: She had requested to go to Vietnam.

"They were very emotional, crying. They were very, very proud, but also very frightened," she recalls. Her dad, a decorated World War II combat veteran, hugged her and told her to take care of herself.

A little over a year later, Furey would come back home a changed person. What she had seen and experienced as a nurse, she says, "was beyond anything civilian life could prepare you for."

Understanding the experience of women like Furey and the long-term health effects of their service in Vietnam is the goal of a new VA study. As many as 10,000 women, most now in their 60s, are expected to take part. The sample will include women who served in Vietnam and, for comparison, those who served stateside or elsewhere in Asia, such as in Japan, Korea, Guam or the Philippines.

"We're going to be looking at current and lifetime prevalence of a range of physical and mental health outcomes," says study co-chair Kathy Magruder, PhD, MPH, an epidemiologist at the Charleston (S.C.) VA Medical Center. She notes that the study is the largest and most comprehensive effort to date to look at this population.

Among the key questions the researchers hope to answer: How many of the women developed posttraumatic stress disorder or depression after their service, and how many cope with these conditions till today? Are these conditions more prevalent among those who served in Vietnam, and to what extent have they led to physical health problems?

Magruder says it's difficult to predict whether the prevalence of PTSD will be similar to what was found when smaller groups of Vietnam-deployed women were studied in the 1980s. Then, it was about 8.5 percent.

"There are cases of remission, as well as new onset and delayed onset. There could be new traumas totally unrelated to military service," notes Magruder. "Also, we're using different instruments now—there's a whole new diagnostic system. So we don't know what we're going to find."

Chairing the study with Magruder are Amy Kilbourne, PhD, MPH, a mentalhealth researcher for VA in Ann Arbor; and Han Kang, DrPh, who directs VA's Environmental Epidemiology Service and the War-Related Illness and Injury Study Center in Washington, DC.

About 8,000 of the women VA expects to enroll in the new study were part of earlier research by Kang on birth outcomes. That study, published in 2000, found higher rates of birth defects in the children of women who had served in Vietnam compared with those who had served elsewhere. The causes for the increased risk remain unknown, but researchers believe they may include exposure to herbicides such as Agent Orange.

The new study will include mail surveys, phone interviews and reviews of medical records. Teasing out the complex links between Vietnam deployment and various health factors—especially over the course of 40 years—will be a challenge for the researchers.

Says Magruder, "There are two things we can be really certain about—whether they served in Vietnam or elsewhere, and second, their current mental and physical health." She points out that most of the prospective respondents are nurses and have experience reporting health conditions.

In terms of mental conditions, the researchers will ask mainly about PTSD, depression, anxiety and substance abuse. The physical conditions they'll focus on include cardiovascular disease, diabetes, multiple sclerosis, Parkinson's disease, brain cancer, breast cancer, and gynecological cancers. Some of the conditions have been linked in past research to exposure to trauma or environmental toxins; others don't have a particular military tie-in but are common among aging women.

Along with probing the prevalence of various conditions, the researchers will ask about demographics and life and military factors such as years of nursing experience, pre-existing health conditions, childhood traumas, wartime exposures or injuries, homecoming, social support, and health behaviors, such as cigarette smoking or alcohol use.

Magruder points out that even though four decades have passed since the war, she and her team expect that study volunteers will harbor vivid memories of their wartime experiences and how they coped afterward. Many may still struggle with mental or physical illness linked to their service. "For many of these women, the effects of the war are still present in their daily lives," says Magruder.

Most of the women expected to take part in the study have not been regular users of VA health care. Nonetheless, VA—which has ramped up programs for women in recent years—will use the results to improve care and services for this Vietnam-era population.

"These women, for the most part, are in their early 60s," notes Magruder. "They may have a lot more years. It's important for us to know what they're dealing with."

The findings may also shed light on what the newest generation of women veterans—those returning from Iraq and Afghanistan—may face in the years ahead.

This article originally appeared in the September 2009 issue of VA Research Currents.