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Greater medical burden seen in Veterans with PTSD


A U.S. Army soldier patrols an alleyway in Diyala province, Iraq, in 2009. A U.S. Army soldier patrols an alleyway in Diyala province, Iraq, in 2009. (Photo by Staff Sgt. Ali E. Fisek/USAF)

A large study by a VA and Stanford University team shows that among the newest generation of Veterans enrolled in VA health care, those with a mental health condition—especially posttraumatic stress disorder (PTSD)—tend to have more physical ailments.

The results, published online Sept. 18 in the Journal of General Internal Medicine, are not surprising in light of past research on the link between emotional stress and physical illness. But the findings may help guide VA as it continues expanding services to care for returning Veterans.

"In caring for Veterans returning with PTSD, we should account not only for their mental health needs, but also for their increased medical needs," says lead author Susan Frayne, MD, MPH, with the VA Palo Alto Health Care System and Stanford University.

She says examples of areas where VA needs to assure ample capacity, based on the study results, include physical therapy and pain clinics to address high levels of musculoskeletal conditions; behavioral medicine and nutrition services to help with common conditions such as obesity; and clinics that specialize in women's health care to respond to the particularly heavy burden of medical illness seen in women with PTSD.

Findings based on 90,000 VA patients

The researchers examined the records of more than 90,000 Iraq and Afghanistan Veterans who used VA outpatient care in fiscal year 2006–2007. The majority had received a diagnosis of at least one mental health condition. About 35 percent of men and 27 percent of women had PTSD.

The link between PTSD and medical (non-mental) illness was stronger among women than among men. Women with PTSD had a median of 7 medical conditions, versus 4.5 for women with no mental health diagnosis. The most common physical ailments for women were lower-back problems, headaches and lower-extremity joint disorders. Men with PTSD had a median of 5 medical conditions, versus 4 for men with no mental health diagnosis. The most common complaints for men were similar to those of women—for example, back and knee problems—but also included hearing loss.

Frayne, who conducts research for VA's Center for Health Care Evaluation and Women's Health Center of Excellence, both based in Palo Alto, says her team's study is among the first to provide a broad overview of the significant medical burden among newly returned Veterans with PTSD. The study checked for 222 specific medical conditions, from cancer to digestive trouble.

Related research by a team at the San Francisco VA Medical Center, published in January 2010, also in the Journal of General Internal Medicine, yielded similar findings: Iraq and Afghanistan Veterans with mental health conditions, particularly PTSD, used significantly more non-mental health services than those with no mental health diagnosis. The study was based on the records of nearly 250,000 Veterans who used VA care for the first time between 2001 and 2007.

In light of the trend seen across both studies, Frayne notes that early intervention for both physical and mental illness will be critical in helping Veterans avoid longterm health problems.

As to the reasons underlying the connection between PTSD and medical illnesses, Frayne offers several theories.

"One possibility," she says, "is that PTSD itself leads to increased risk of medical illness. One way this could happen is that PTSD can cause changes in the neuroendocrine system in the body, which might affect other biological processes."

Another possibility is that "PTSD itself does not cause medical conditions, but that whatever caused the PTSD also simultaneously caused the medical condition." An example would be a service member who was exposed to a blast that broke a bone and also caused emotional trauma.

Despite the trends seen in the study, Frayne emphasizes that not all Veterans with PTSD have a greater array of health problems.

"While it's important to take medical conditions in patients with PTSD very seriously," she says, "it's also important not to assume that all returning Veterans have these conditions."

This article originally appeared in the October-November 2010 issue of VA Research Currents.