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Chemical: trichloroethylene

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Email link to this page: http://actor.epa.gov/actor/GenericChemical?casrn=79-01-6

(No Structure)
GCID
466383
MESH DESCRIPTION
A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment. : A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment. : Anesthetics, Inhalation : Solvents : Anesthetics, Inhalation : Solvents
CASRN
79-01-6
FORMULA
C2HCl3
MW
131.388
SMILES
C(=C(Cl)Cl)Cl
SOURCE
DSSTOX
Synonyms
"1,1,2-Trichloroethylene"
"Ethene, trichloro-"
"Ethylene trichloride"
"Ethylene, trichloro-"
"TCE"
"Trichlorethylene"
"Trichloride, Ethinyl"
"Trichloroethene"
"Trichloroethylene"
1,1,2-trichloroethene
1,1,2-Trichloroethene [Trichloroethylene, TCE]
1,1,2-trichloroethylene
1,1,2-Trichloroethylene (TCE)
1-CHLORO-2
79-01-6
ACETYLENE TRICHLORIDE
AI3-00052
ALGYLEN
ANAMENTH
BENZINOL
C06790
Caswell No 876
CECOLENE
CHLORILEN
Chlorylea
D014241
DENSINFLUAT
ECB# 18
EINECS 201-167-4
EPA Pesticide Chemical Code 081202
ETHENE
Ethene, 1,1,2-trichloro-
Ethene, trichloro-
Ethinyl Trichloride
ETHYLENE
ETHYLENE TRICHLORIDE
ETHYLENE, TRICHLORO -
FLECK-FLIP
FLOCK FLIP
FLUATE
GERMALGENE
HAP NO 159
LANADIN
LETHURIN
NARCOGEN
NARKOSOID
NCGC00091202-01
NCI-C04546
NIALK
NSC 389[Bretherick
NULL
PC Code 081202
PERM-A-CHLOR
Pesticide Code: 081202[U.S. Environmental Protection Agency/Office of Pesticide Program's Chemical Ingredients Database on Trichloroethylene (79-01-6). Available from
PETZINOL
PHILEX
TCE
THRETHYLEN
THRETHYLENE
TRETHYLENE
TRI
TRI-PLUS
TRIASOL
Trichloraethen (German)
Trichloraethylen
TRICHLORAN
TRICHLOREN
Trichlorethen
Trichlorethene
Trichlorethene (French)
TRICHLORETHYLEN
TRICHLORETHYLENE
Trichloride, Ethinyl
Trichloro-ethylene
Trichloroehene
TRICHLOROETHENE
Trichloroethene (1,1,2-) (Trichloroethylene)
Trichloroethene (TCE)
Trichloroethene (Trichloroethylene)
Trichloroethene (Trichloroethylene, TCE)
Trichloroethylen
Trichloroethylene
Trichloroethylene (1,1,2-trichloroethene)
Trichloroethylene (TCE)
Trichloroethylene (Trichloroethene)
Trichloroethylene (Trichloroethene,TCE, CAS number 79-01-6)
Trichloroethylene (Trichloroethylene 1,1,2-)
Trichloroethylene (without epichlorohydrin)
trichloroethylene, , trichloroethene
trichloroethylene; trichloroethene
TRICLENE
Tricloretene (Italian)
Tricloroetilene (Italian)
Trielin
Trielina
Trielina (Italian)
TRIKLONE
Trilene
TRIMAR
VESTROL
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Compounds included in USGS Source Water-Quality Assessment (SWQA) studies
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Production and Release
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EPA TRI Release levels for year 2010
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EPA TRI Chemical List for 2009
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European Parliment Environmental Quality Standards (EQS) For Priority Substances And Certain Other Pollutants in Surface Water
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FDA EAFUS - Everything Added to Food in the U.S.
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FDA Inactive Ingredients Database
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Health Canada Guidelines for Canadian Drinking Water Quality
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Agents Classified by the IARC Monographs, Volumes 1-102
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Risk Assessment Information system toxicity profiles
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UNECE PRTR Expected releases and transfers
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Compounds included in USGS Source Water-Quality Assessment (SWQA) studies
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Utah Ground Water Quality Standards (GWQS)
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Wisconsin groundwater monitoring results for 2000
In Vitro
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DSSTox ArrayExpress DSSTox Annotation
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NLM TOXNET GENETOX URL
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NLM TOXNET GENETOX Data
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qHTS Assay for Compounds that Induce Erasure of Genomic Imprints
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qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease
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qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate
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qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate
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qHTS Assay for Identification of Small Molecule Inducers of Hypoxia Response
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qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)
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qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM)
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VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity
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qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)
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qHTS for inhibitors of ROR gamma transcriptional activity
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qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction
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Cell Viability - BJ
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Cell Viability - Jurkat
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Cell Viability - Hek293
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Cell Viability - HepG2
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Cell Viability - MRC5
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Cell Viability - SK-N-SH
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IkB Signaling
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qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1)
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qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase: hit validation
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qHTS Assay for Inhibitors of GCN5L2
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qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a
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JNK3 AlphaScreen Assay
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Cell Viability - N2a
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Cell Viability - NIH 3T3
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Cell Viability - HUV-EC-C
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Cell Viability - H-4-II-E
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Cell Viability - SH-SY5Y
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Cell Viability - Renal Proximal Tubule
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Cell Viability - Mesenchymal
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Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent)
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Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent)
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qHTS Assay for Disrupters of an Hsp90 Co-Chaperone Interaction
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qHTS Assay for Tau Filament Binding
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qHTS Assay for Inhibitors of DNA Polymerase III Holoenzyme System
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qHTS Assay for Inhibitors of YjeE
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Cellular Toxicity (caspase-3) HepG2
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Cellular Toxicity (caspase-3) Jurkat
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Cellular Toxicity (caspase-3) HUV-EC-C
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Cellular Toxicity (caspase-3) SHSY5Y
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Cellular Toxicity (caspase-3) BJ
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Cellular Toxicity (caspase-3) MRC-5
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Cellular Toxicity (caspase-3) Mesangial
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Cellular Toxicity (caspase-3) SK-N-SH
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Cell signaling CRE-BLA (Fsk stim)
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Cellular Toxicity (caspase-3) H-4-II-E
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Cellular Toxicity (caspase-3) Hek293
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Cellular Toxicity (caspase-3) N2a
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Cellular Toxicity (caspase-3) NIH 3T3
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Cellular Toxicity (caspase-3) Renal Proximal Tubule
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qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Green Fluorophore)
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qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore)
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qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2)
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qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4
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qHTS Assay for Activators of Cytochrome P450 3A4
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qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II)
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qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)
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qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7
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qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Red Fluorophore)
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qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4
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qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)
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qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1
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qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature
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qHTS Assay for Anthrax Lethal Toxin Internalization
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Cell Viability - LYMP2-001
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qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region
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qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature
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qHTS Assay for Modulators of Hemoglobin Beta Chain Splicing
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qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor
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qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293
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MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Dead Cells
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MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Live Cells
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Cell Viability - LYMP1-002 - Assay at 16 hr
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MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Live Cells
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MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Dead Cells
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MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Dead Cells
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MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Live Cells
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Cell Viability - LYMP1-003 - Assay at 24 hr
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Cell Viability - LYMP1-003 - Assay at 40 hr
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Cell Viability - LYMP2-003
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Cell Viability - LYMP2-004
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Cell Viability - LYMP2-005
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Cell Viability - LYMP2-009
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Cell Viability - LYMP2-011
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Cell Viability - LYMP2-013
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Cell Viability - LYMP2-015
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Cell Viability - LYMP2-017
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Cell Viability - LYMP2-019
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Cell Viability - LYMP2-021
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Cell Viability - LYMP2-023
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Cell Viability - LYMP2-025
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Cell Viability - LYMP2-002
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Cell Viability - LYMP2-006
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Cell Viability - LYMP2-007
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Cell Viability - LYMP2-008
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Cell Viability - LYMP2-010
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Cell Viability - LYMP2-012
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Cell Viability - LYMP2-014
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Cell Viability - LYMP2-016
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Cell Viability - LYMP2-018
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Cell Viability - LYMP2-020
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Cell Viability - LYMP2-022
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Cell Viability - LYMP2-024
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Cell Viability - LYMP2-026
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Cell Viability - LYMP1-002 - Assay at 24 hr
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Cell Viability - LYMP1-002 - Assay at 40 hr
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qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay
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ChEMBL activity data
Use
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Chemicals Known to Cause Cancer or Reproductive Toxicity
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CARB Consumer product solvent database
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CARB VOCs in cleaning products
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CDC Savannah River Site (SRS) Study chemical information used to develop or support chemical release estimates
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Literature Survey for Substances which may be emitted from Electric and Electronic Equipment
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Substances Emitted from Electrical and Electronic Products
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EDSPDB Occupational Exposure Data
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EPA study: Polar Organic Compounds in Fragrances of Consumer Products
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EUROPA Drug Profiles for controlled drugs
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FDA Inactive Ingredients Database
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FDA Total Diet Study (TDS) PIC for FY2003
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FDA Total Diet Study (TDS) PIC for FY2002
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FDA Total Diet Study (TDS) PIC for FY2001
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FDA Total Diet Study (TDS) PIC for FY2000
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FDA Total Diet Study (TDS) PIC for FY1999
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FDA Total Diet Study (TDS) PIC for FY1998
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FDA Total Diet Study (TDS) Summary for 1991-2003
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Global Automotive Declarable Substance List (GADSL)
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Global Automotive Declarable Substance List (GADSL) for 2011
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INCHEM JMPR (Joint Meeting on Pesticide Residues) Monographs
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Maine Department of Health List of Chemicals of High Concern (CHC)
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NHEXAS Minnesota
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NIOSH Immediately Dangerous Chemicals
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URLs for NIOSH Immediately Dangerous Chemicals
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NIOSH National Occupational Exposure Survey (NOES) data
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NIOSH permissible exposure limits (PELs) set by OSHA
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NIOSH list of potential occupational carcinogens
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Total Use, Substances in Preparations in Nordic Countries
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Industrial use, Substances in Preparations in Nordic Countries
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Exposure, Substances in Preparations in Nordic Countries
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Use by Category, Substances in Preparations in Nordic Countries
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Detailed Use by Category, Substances in Preparations in Nordic Countries
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Migration of substances from in-situ applied epoxy resin coatings
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USGS Groundwater Special Study: The Oahu National Water-Quality Assessment (VOCs)
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ChEMBL activity data
International Safety Card
0081
PubMed via Mesh
Notes
Data CollectionNote
Chemicals with same structure but different CASRN
DetailsImageCASRNPreferred NameHazardChronic ToxicityCarcinogenicityGenotoxicityDevelopmental ToxicityReproductive ToxicityFood SafetyBiomonitoring
detailsImage Not Found52037-46-41,1,2-Trichloroethylene

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