for Veterans and the Public
Kaletra (lopinavir/ritonavir)
- Type of Drug: Protease Inhibitor
- Once HIV has infected a cell and made copies of itself, it uses an enzyme called protease to process itself correctly so it can be released from the cell to infect other cells. Protease inhibitors work by blocking that enzyme.
Approved adult dosing
Lopinavir 200 mg + ritonavir 50 mg in a single tablet
two tablets, two times a day
Morning
Kaletra
Evening
Kaletra
Lopinavir 200 mg + ritonavir 50 mg in a single tablet
four tablets, once a day
Daily
Kaletra
Note: This once-daily dosage may not be appropriate for people who have taken other HIV medications in the past; consult your medical provider
Notes on taking this medication
- Take with or without food
- Kaletra interacts with many other drugs; persons using Kaletra with those drugs may need an adjustment to their dose of Kaletra or the other drugs; consult your medical provider
Side effects
- Nausea; vomiting; diarrhea; headaches
- Liver inflammation and increased liver enzyme levels
- Elevations in cholesterol and triglycerides
- Abnormal accumulation of body fat
- Increased blood sugar
See accompanying chart: Tips for Common Side Effects
My doctor's instructions
Disclaimer: This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.