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Clinical Questions Addressed by the CER (2 of 2)

In preparing the report on which this CME activity is based, the authors aimed to answer seven Key Questions. Key Questions 4–7 are listed below:

KQ4. In adults being screened for obstructive sleep apnea (OSA), what are the relationships between apnea-hypopnea index (AHI) or oxygen desaturation index, and other patient characteristics with long term clinical and functional outcomes?

KQ5. What is the comparative effect of different treatments for OSA in adults?

KQ6. In OSA patients prescribed nonsurgical treatments, what are the associations of pretreatment patient-level characteristics with treatment compliance?

KQ7. What is the effect of interventions to improve compliance with device use (positive airway pressure, oral appliances, positional therapy) on clinical and intermediate outcomes?

Presentation: Diagnosis and Treatment of Obstructive Sleep Apnea in Adults

Authors: Bradley N. Gaynes, MD, MPH, Mark E. Kunik, MD, PhD and Linda J. Lux

Keywords: comparative effectiveness | systematic review | key question

References:

Balk EM, Moorthy D, Obadan NO, et al. Diagnosis and Treatment of Obstructive Sleep Apnea in Adults. Comparative Effectiveness Review No. 32 (Prepared by Tufts Evidence-based Practice Center under Contract No. 290-2007-10055-I). Rockville, MD: Agency for Healthcare Research and Quality; July 2011. AHRQ Publication No. 11-EHC052-EF.