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Currency [0]/Explanatory TextG5Explanatory Text % 0Good;Good  a%1 Heading 1G Heading 1 I}%O2 Heading 2G Heading 2 I}%?3 Heading 3G Heading 3 I}%234 Heading 49 Heading 4 I}% 5InputuInput ̙ ??v% 6 Linked CellK Linked Cell }% 7NeutralANeutral  e%3Normal %8 Normal 10 9Normal 2: Normal 2 2 ;Normal 3 <Normal 4 =Normal 57Normal 5 % >Normal 6 ?Normal 7@ Normal 7 2,A'Normal_NCRI_Proposed_elements_19Jul2010 BNoteb Note   CNote 2fNote 2   DOutputwOutput  ???%????????? ???E$PercentF Percent 2 GTitle1Title I}% HTotalMTotal %OOI Warning Text? Warning Text %XTableStyleMedium9PivotStyleLight16`ReadMe'lClinical DE Glossary 2012-08-03!  ;bZ    3 A@@   @The controlled terminology in this spreadsheet supports the CDISC Clinical Data Element Glossary. It represents all therapeutic area data elements developed and in production to date. A data element is an atomic unit of data that has a precise meaning or precise semantics. Additional data elements will be developed on an ongoing basis to support all CDISC therapeutic area standards.Column DescriptionCode (Column A) qUnique numeric code randomly generated by NCI Thesaurus (NCIt) and assigned to individual CDISC controlled terms.Codelist Code (Column B) FUnique numeric code randomly generated by NCI Thesaurus (NCIt) and assigned to the SDTM parent codelist names. This code is repeated for each controlled term (aka permissible value) belonging to a codelist. **NOTE - light blue highlighting is used to identify the beginning of a new SDTM codelist and its applicable term set. (Codelist Extensible (Yes/No) (Column C)  'PDefines if controlled terms may be added to the codelist. New terms may be added to existing codelist values when the codelist has "Yes" in Column C as long as the terms are not duplicates or synonyms of existing terms. The expectation is that sponsors will use the published controlled terminology as a standard baseline and codelists defined as  extensible (or "Yes") may have terms added by the sponsor internally. For codelists with "No" in Column C sponsor organizations may not add to the published lists. Suggestions for new terms may be requested through the New Term Request Page. Codelist Name (Column D) Contains the descriptive name of the codelist. As with the Codelist Code, the Codelist Name is repeated for each controlled term belonging to a codelist./!CDISC Submission Value (Column E) IMPORTANT COLUMN: Currently this is the preferred term as determined by the therapeutic area working group. Each value corresponds to the CDISC Clinical Data Element Glossary codelist as indicated by light blue shading.CDISC Synonym(s) (Column F) This identifies the applicable synonyms for a CDISC Preferred Term in Column F. **NOTE - this is especially important in instances where a Test name or Parameter Test name contains a corresponding Test Code or Parameter Test Code. CDISC Definition (Column G)  This identifies the CDISC definition for a particular term. In many cases an existing NCI definition has been used. The source for a definition is noted in parentheses (e.g. NCI, CDISC glossary).NCI Preferred Term (Column H) ,This identifies the NCI preferred name for a term as identified in NCIt. **NOTE - This column designates the human readable, fully specified preferred term corresponding to the NCI c-code, and is especially helpful for searching NCIt to get the entire concept with links to all instances of the term.Code Codelist CodeCodelist Extensible (Yes/No) Codelist NameCDISC Submission ValueCDISC Synonym(s)CDISC DefinitionNCI Preferred TermNoClinical Data Element GlossaryCLINDEEThe terminology relevant to the CDISC Clinical Data Element Glossary.0CDISC Clinical Data Element Glossary TerminologyC2868 AmyloidosisxA disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.C84571*Arrhythmogenic Right Ventricular DysplasiaA rare genetic disorder characterized by cardiomyopathy affecting the right ventricle. The heart tissue is replaced by fibrous and adipose tissues. It is characterized by ventricular arrhythmia and right ventricular dysfunction. It is a cause of sudden death.C99704Arterial Dissection%A tear within the wall of the artery.C84473Atrial Septal DefectA congenital disorder characterized by the presence of a defect (opening) in the septum that separates the two atria of the heart.C29576Beta-Adrenergic AntagonistKNatural or synthetic beta adrenergic antagonists selectively or non-selectively blocking or diminishing physiologic beta-adrenergic agonist actions on the sympathetic system. This group of antagonists are generally used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.C49068BlindedA characteristic of experimental design in which one or more groups involved (receiving, administering, or evaluating intervention) are unaware of which intervention any particular subject is receiving.C99530Bradycardia Arrest0Cardiac arrest that was a result of bradycardia.C50479Cardiac ArrestVCardiac arrest is the non-fatal, sudden cessation of cardiac activity so that the victim subject/patient becomes unresponsive, with no normal breathing and no signs of circulation. Cardiac arrest should be used to signify an event as described above that is reversed, usually by CPR, and/or defibrillation or cardioversion, or cardiac pacing.C99529Cardiac Pacemaker OversensingrInappropriate pacemaker detection of electrical signals not related to cardiac depolarization of the lead chamber.C99541Cardiac Pacemaker UndersensingCFailure of pacemaker to detect appropriate cardiac depolarizations.C73502Cardiac PerforationThe presence of an acquired hole in the heart. Cardiac perforation may or may not be symptomatic and may or may not be self sealing.C50481Cardiac TamponaderCompression of the heart caused by increased intrapericardial pressure due to the collection of blood or fluid in the pericardial space. Cardiac tamponade should usually be documented by either: Echocardiogram showing pericardial fluid and signs of tamponade such as right heart compromise, or systemic hypotension due to pericardial fluid compromising cardiac function.C80430Cardiac Therapeutic Procedure\A therapeutic procedure to treat pathologic structural or functional disorders of the heart.C99546Cardiac Valve ProcedureSurgical replacement and/or repair of a cardiac valve, by any approach. This includes percutaneous valve procedures and valvuloplasty.C50482Cardiogenic ShockCardiogenic shock is defined as a sustained (greater than30 minutes) episode of systolic blood pressure less than90 mm Hg, and/or cardiac index less than2.2 L/min/m2 determined to be secondary to cardiac dysfunction, and/or the requirement for parenteral inotropic or vasopressor agents or mechanical support (e.g., Intra aortic balloon pump (IABP), extracorporeal circulation, ventricular assist devices) to maintain blood pressure and cardiac index above those specified levels.C2938Cerebral Artery DiseaseA disorder resulting from inadequate blood flow in the arteries that supply the brain. The diagnostic criteria may include current or previous history of the following: Ischemic stroke, TIA, Noninvasive or invasive arterial imaging test demonstrating greater than or equal to 50% stenosis of any of the major extracranial or intracranial vessels to the brain; Previous cervical or cerebral artery revascularization surgery or percutaneous intervention.Cerebrovascular DisorderC80078Chronic Kidney DiseaseChronic kidney disease is defined as either kidney damage or GFR less than 60 ml/min/1.73 m2 for greater than or equal to 3 months. Kidney damage is de?ned as pathologic abnormalities or markers of damage, in< cluding abnormalities in blood or urine tests or imaging studies.C98541Chronic Lung Disease A persistent non-neoplastic disorder of the lungs. Representative examples include: chronic obstructive pulmonary disease, chronic bronchitis, emphysema, pulmonary fibrosis, pneumoconiosis, asbestosis, atelectasis, radiation induced pneumonitis, and radiation fibrosis.Chronic Lung DisorderC99542Common Cardiac VentricleCommon ventricle is an umbrella term used to describe several very different complex congenital heart defects that share the same problem: the heart has only one functional ventricle (anatomically right or left or indeterminate) supplying the systemic circulation. These defects include tricuspid atresia, hypoplastic left or right heart syndrome, double outlet right ventricle, double inlet left ventricle, and other forms of single ventricle defects.Common Ventricle DisorderC390Contrast AgentSubstances administered during diagnostic procedures that allows delineation of internal structures. Contrast agents appear opaque due to the difference in absorption of X-rays or other electromagnetic waves and surrounding tissue.C26732Coronary Artery DiseaseNarrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction.C80475Coronary Lesion TreatedYThe coronary lesions treated during a PCI (Percutaneous Coronary Intervention) procedure.Coronary Lesions TreatedC49343Deep Venous Thrombosis>A blood clot (thrombus) in a deep vein in the lower extremity.Deep Vein ThrombosisC2982 DepressionDepressed Mood,A melancholy feeling of sadness and despair.C2985Diabetes MellitusA metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.C99532Diabetes TherapyRA therapeutic modality used to aide in the management of an individual's diabetes.C15221DialysisA procedure to remove toxic substances from the blood that is used in patients with end-stage chronic kidney disease or acute kidney failure. This includes hemodialysis and peritoneal dialysis.C99554Disease PresentationqThe compilation of symptoms and/or clinical manifestation of any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function.C80385 DyslipidemiaA lipoprotein metabolism disorder characterized by decreased levels of high-density lipoproteins, or elevated levels of plasma cholesterol, low-density lipoproteins and/or triglycerides.C84681Ebstein's AnomalyA rare congenital heart malformation characterized by apical displacement of the tricuspid valve into the right ventricle. The defect involves both the right ventricle and the tricuspid valve, and can lead to cardiomyopathy and tachyarrhythmias.Ebstein AnomalyC80398)Family History of Coronary Artery Disease?History of a first-degree relative (less than 55 years for male relatives or less than 65 years for female relatives) having had any of the following: coronary artery disease, myocardial infarction, coronary artery bypass graft surgery, percutaneous coronary intervention, or sudden cardiac death without obvious cause.C80397&Family History of Sudden Cardiac DeathA first-degree relative (parent, sibling, child) documented to have died suddenly of a presumed cardiac etiology without other obvious cause.History of Sudden Cardiac DeathC16588 FluoroscopyExamination of the tissues and deep structures of the body by x-ray, using the fluoroscope, a device that produces an image when x-rays strike a fluorescent screen.C99533Fractional Flow ReserveEA lesion-specific measure of stenosis severity within a blood vessel.!Fractional Flow Reserve of VesselC99534Fractional Flow Reserve RatioThe pressure distal to the stenosis divided by the pressure proximal to the stenosis. This ratio is equal to maximum blood flow in the vessel with stenosis divided by the maximum hypothetical blood flow without stenosis.'Fractional Flow Reserve Ratio of VesselC84742Great Vessels TranspositionTransposition of Great VesselsTransposition of the great vessels is a congenital heart defect in which the two main arteries leaving the heart are reversed (transposed).C50577 Heart FailureInability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention; or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction.C50579Hematoma~A localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel.C99536Hemodynamic InstabilityA state of hypoperfusion that does not support normal organ perfusion or function. It can include periods of reduced, unstable, or abnormal blood pressure with near syncope, or episodes of syncope.C95803$Hemorrhagic Cerebrovascular AccidentAn acute episode of focal or global cerebral or spinal dysfunction caused by intraparenchymal, intraventricular, or subarachnoid hemorrhage.C50582 Hemothorax$Accumulation of blood in the thorax.C3108 HIV InfectionAny state accompanied by evidence of human immunodeficiency virus in the body (positive test for HIV genome, cDNA, proteins, antigens, or antibodies).C99516Home Oxygen TherapyTreatment in which a storage tank of oxygen or a machine called a compressor is used at home to give oxygen to people for the treatment of chronic lung disease.C3117 HypertensionPathological increase in blood pressure defined as one of the following: History of hypertension diagnosed and treated with medication, diet, and/or exercise; On at least 2 separate occasions, documented blood pressure greater than 140 mm Hg systolic and/or 90 mm Hg diastolic in patients without diabetes or chronic kidney disease, or blood pressure greater than 130 mm Hg systolic or 80 mm Hg diastolic in patients with diabetes or chronic kidney disease; Currently on pharmacological therapy for the treatment of hypertension.C34449Hypertrophic CardiomyopathyA condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract.C99535Intravascular UltrasoundIVUSAn invasive procedure in which sound waves (called ultrasound) are bounced off of vascular tissues from within the vessel and the echoes produce a picture (sonogram).C95802!Ischemic Cerebrovascular AccidentIschemic stroke is defined as an acute episode of focal cerebral, spinal, or retinal dysfunction caused by infarction of central nervous system tissue.C80413Left Heart CatheterizationThe passage of a catheter into the left ventricle for the purposes of angiography, measurement of ventricular pressures, and/or oxygen saturation.C80492-Left Main Coronary Artery Stenosis Percentage~Percent luminal narrowing of the left main coronary artery, at the point of maximal stenosis of the left main coronary artery..Left Main Coronary Artery Stenosis, PercentageC99544(Left Ventricular Non-Compaction Syndrome1This is an uncommon congenital abnormality where the left ventricular myocardium fails to compact during embryonic development, leading to cardiomyopathy with a variable degree of ventricular dysfunction. There is genetic heteroge< neity and phenotypic variability. Characteristically, there are typically deep trabeculations in the non-compacted area, with varying proportions of the LV myocardium compacted. LV non-compaction is associated with rhythm abnormalities including Wolff-Parkinson-White syndrome, conduction defects, and ventricular tachyarrhythmias.C99547 Life Expectancy of an Individual'Estimate of future survival of subject.C99540Mechanical Circulatory SupportUse of a device to replace the function of a cardiac ventricle. This includes use of cardiopulmonary bypass, left ventricular assist device (LVAD), intra-aortic balloon pump (IABP) and/or extracorporeal membrane oxygenation (ECMO).C99539/Mechanical Circulatory Support Placement TimingIA description of when a mechanical circulatory support device was placed.C50646Medical ContraindicationA symptom or medical condition that makes a particular treatment or procedure inadvisable because a person is likely to have a bad reaction.C99551Non-system Delay,A patient condition that delays a procedure.Patient Condition DelayC35205Old Myocardial Infarction History of Myocardial InfarctionDocumented history of previous myocardial infarction (MI), typically with objective evidence via positive biomarkers of myocardial necrosis.C15409!Packed Red Blood Cell TransfusionfThe intravenous administration of red blood cells (whole blood without the plasma) into an individual.C84496Peripheral Arterial DiseaseVA disorder of the arteries supplying the upper and lower extremity and the visceral organs. This includes the mesenteric arteries, the renal arteries and the aorta. This excludes cerebrovascular arterial disease. This is defined as any one of the following: Claudication, either with exertion or at rest, amputation for arterial vascular insufficiency, vascular reconstruction, bypass surgery, or percutaneous intervention to the extremities, documented aortic aneurysm with or without repair, vascular angiography demonstrating a 50% or greater stenosis of a major peripheral arterial vessel, positive noninvasive test for peripheral arterial disease, including an ankle-brachial index less than or equal to 0.9, ultrasound, magnetic resonance or computed tomography imaging demonstrating a 50% or greater stenosis of a major peripheral arterial vessel.Peripheral Arterial DisorderC99552Permanent Cardiac Pacemaker=A pacemaker where the generator is implanted inside the body.C38006 Pneumothorax/Abnormal presence of air in the pleural cavity.C99531Primary Cause of DeathCThe first significant abnormal event which ultimately led to death.C99545Primary Valvular DiseasePrimary valvular heart disease is defined by heart disease that is primarily due to a valvular defect or abnormality. Valve disease that is felt to be significant but does not fulfill the definition for primary valvular heat disease is considered contributory valvular heart disease.Primary Valvular DisorderC50713Pulmonary EmbolismThe obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung.C34995 SarcoidosisAn idiopathic inflammatory disorder characterized by the formation of non-necrotizing epithelioid granulomas which contain giant cells. It usually affects the lungs, lymph nodes, liver, eyes, and skin. Cardiac involvement is also possible.C99709Significant Arterial DissectionKA dissection that impairs flow. These include Type C (a persisting contrast medium extravasations in the presence of ischemia), Type D (a spiral filling defect with delayed but complete distal flow) , Type E (persistent filling defect with delayed antegrade flow) and Type F (filling defect with impaired flow and total occlusion).C100053Sinus Node FunctionQDescriptions of electrical activity and conduction involving the sinoatrial node. Sinus Node Functional AssessmentC26884 Sleep Apnea~Cessation of breathing for short periods during sleep. It is classified as obstructive, central, or mixed obstructive-central.C99553 Sleep Study3Measurement of physiologic parameters during sleep.C99538Structural Heart Abnormalities]An anatomic deformity of the heart, structures within the heart, ventricles or great vessels.Structural Heart AbnormalityC35053SyncopeSudden loss of consciousness with loss of postural tone, not related to anesthesia, with spontaneous recovery as reported by patient or observer. A subject may experience syncope when supine. Syncope is often caused by insufficient blood supply to the brain.C18059 Tobacco Use=Use of tobacco in any form i.e. smoking, chewing or sniffing.C99537Venous ThromboembolismiOcclusion of the lumen of a vein by a thrombus that has migrated from a distal site via the blood stream.C26924Ventricular ArrhythmiaRAbnormal heart beat resulting from a pathologic process in the cardiac ventricles.C84506Ventricular Septal DefectThe presence of a defect (opening) in the septum that separates the two ventricles of the heart. The VSD can be congenital or acquired.C995227Ventricular Tachycardia/Ventricular Fibrillation ArrestSA cardiac arrest attributed to ventricular tachycardia or ventricular fibrillation.C25717 Vital StatusmThe state or condition of being living or deceased; also includes the case where the vital status is unknown.C62749Whole Blood TransfusionPThe injection of whole blood or a blood component directly into the bloodstream.C101836Red Blood Cell Transfusion$Abnormal Intraventricular ConductionAntitachycardia Pacing Aorta DiseaseAppropriate TreatmentArterial Access Closure MethodArterial Access SiteAtrial ArrhythmiaCardiac AblationCardiac Diagnostic ProcedureCardiac RehabilitationCardiac Stent PlacementCardiac Valve Injury(Cardioverter Defibrillator Shock TherapyChagas Disease'Chronic Total Coronary Artery OcclusionComfort MeasuresConduction BlockCoronary Artery GraftCoronary Artery PerforationCoronary LesionCoronary Lesion ComplexityCoronary Reperfusion$Coronary Sinus/Left Ventricular LeadCoronary Venous Dissection"Coronary Vessel Bifurcation LesionCulprit LesionDefibrillation ThresholdDevice DeploymentDiagnostic Coronary AngiographyElectrophysiology StudyExercise Counseling ExplantationGiant Cell MyocarditisGuidewire Across Lesion&Implantable Cardioverter Defibrillator ImplantationImplantation SiteIn Situ Existing LeadIn Stent RestenosisIntra-Aortic Balloon PumpIntracoronary DeviceIschemic Risk ScoreLead Dislodgement Lead FunctionLead Perforation Lead StatusLeft Ventricular AneurysmLuminal Carotid ThrombusMyocardial Perfusion ImagingNon-Invasive Stress TestingPeripheral EmbolusPeripheral Nerve InjuryPost-Procedure Pre-ProcedureProcedure Urgency Status RegurgitationReimplantationRenal Artery Disease Re-operationSeveritySmoked TobaccoSmokeless TobaccoStenosis)Stress Cardiac Magnetic Resonance ImagingStress EchocardiographySubstance Adverse EventSubstance AllergyTobacco CounselingTransplant Waiting ListUndetermined StrokeFUpper Limit of Vulnerability for Induction of Ventricular FibrillationVenous ObstructionC99543C101245C101253C101247C100057C100056C80503C100068C100084C101234C100080C100069C101251C84629C100062C15292C34665C100064C100083C100063C100066C100067C80463C100070C101233C100072C101236C101231C100085C80414C100073C101235C101248C97055C100082C93238C51982C77678C101239C100081C100087C101232C100074C101241C101238C101246C101240C102654C100077C102676C100075C101249C101250C100059C100058C101230C50726C101242C101254C50830C25676C100079C892C50754C80409C80407C101243C3114C101244C100078C3390C101237C101252An atypical passage of electrical impulses through the cardiac ventricles. This includes fascicular bl< ocks, bundle branch blocks, non-specific conduction delays and ventricular pacing.Delivery of electrical impulses to the heart at a faster rate than the intrinsic rate during an episode of tachycardia, in an attempt to terminate the abnormal tachycardia.]Pathology involving the thoracic, thoracoabdominal, or abdominal aorta (including aneurysms).Correct activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects.A device or treatment used to stop bleeding and close the location of arterial entry following a percutaneous coronary intervention.[Anatomical location where an artery was accessed for a diagnostic or therapeutic procedure.MAbnormal heart beat resulting from a pathologic process in the cardiac atria.bA procedure intended to eliminate or modify a focus or re-entry circuit that causes an arrhythmia.AProcedure to evaluate the structure and/or function of the heart.A medically supervised program to improve the health and well-being of people who have heart problems. This may include exercise training, education on heart healthy living, and/or counseling to reduce stress.A procedure performed during a percutaneous coronary intervention in which a device is deployed into the lumen of a coronary artery to expand and support the vessel wall such that the vessel remains patent and blood flow is uninhibited.An event that causes abnormal valve function. This is usually a tear in leaflet or chordae tendineae and manifests as a new regurgitant.Delivery of strong electrical impulses by a cardioverter defibrillator to return the electrical activity of the heart to normal.VA parasitic infection caused by Trypanosoma cruzi and transmitted by the reduviid bug. It is characterized by an acute and chronic phase; in the acute phase patients may have fever, malaise, and swelling at the site of the insect bite. In the chronic phase patients develop hepatosplenomegaly, lymphadenopathy, cardiomyopathy and arrhythmias.7Pro-longed complete obstruction of the coronary artery.The patient- and family-centered active holistic care of patients with advanced, progressive disease. Essential components of palliative care are: pain and symptom control, communication regarding treatment and alternatives, prognosis, and available services, rehabilitation services, care that addresses treatment and palliative concerns, intellectual, emotional, social, and spiritual needs, terminal care, support in bereavement. The goal of palliative care is an achievement of the best quality of life for patients and their families.dAn injury to the specialized cardiac conduction system that results in impaired signal transmission.RA vessel segment attached to a coronary artery to facilitate myocardial perfusion.JA dissection that extends through the full thickness of the arterial wall.DPathologic material in a vessel that obstructs myocardial perfusion.qCharacteristics of coronary lesions that contribute to procedural risk during percutaneous coronary intervention.Procedures intended to re-establish normal coronary flow. Reperfusion therapy includes thrombolysis and primary PCI. Reperfusion therapy also includes pre-hospital thrombolytics.{The wire which allows a pacemaker or defibrillator to stimulate the left ventricle, often positioned in the coronary sinus.*A tear within the wall of a coronary vein.Bifurcation LesionvA lesion found in the division of a vessel into at least two branches, each of which is 1.5 mm or greater in diameter.UThe lesion indicated is considered to be responsible for the acute coronary syndrome.`The lowest energy where a defibrillator device terminates an arrhythmia in a particular subject.XThe act of instantiating, positioning or activating a medical device inside of the body.A procedure in which the catheter is passed into the aortic root or other great vessels for the purpose of angiography of the native coronary arteries or bypass grafts supplying native coronary arteries.A cardiac procedure performed under fluoroscopy to determine the area of the heart that is the source of aberrant electrical impulses that give rise to arrhythmias. Aberrant pathways can be terminated by ablation.eThe procedure in which physical activity is used to elicit signs and symptoms of myocardial ischemia.A process by which a health professional creates a regimen of physical activity intended to maintain or improve the health of a subject.KA surgical procedure that removes something that was implanted in the body.An often fatal inflammatory disorder that affects the myocardium. Morphologically, it is characterized by the presence of an inflammatory infiltrate in the myocardial tissue that includes multinucleated giant cells. It is often associated with the presence of an autoimmune disorder, mediated by T lymphocytes. Patients present with arrhythmias and/or heart failure. Heart transplantation is the only treatment option available.A performance measure of procedural success during a percutaneous coronary intervention when a guidewire can be deployed across a coronary artery lesion.A battery-powered electrical impulse generator implanted in patients at risk of sudden cardiac death to detect cardiac arrhythmia and correct it by delivering a jolt of electricity.7A surgical procedure that places something in the body.The anatomic site at which a tissue, graft, or radioactive material is inserted. This term may also refer to the site of the uterus at which the early embryo is attached. Existing LeadlAn insulated electrical conductor designed to connect to an electrical device for which the lead is in situ.9Luminal narrowing within the stented segment of a vessel.,A device placed within the coronary anatomy.MThe relative risk of developing ischemia determined by a cardiac stress test.<Movement of a lead away from the original implantation site.VAn indicator to describe whether the electrical lead device is performing as intended.nPenetration of a lead through an anatomical structure such as systemic vein, coronary vein, or the myocardium.hThe state of an insulated wire designed to conduct energy from an electrical device to an anatomic site.EA bulge or ballooning in the wall of the left ventricle of the heart.;A blood clot (thrombus) in the lumen of the carotid artery.NA procedure that obtains pictures that reflect blood flow in the heart muscle.{Procedures intended to evaluate cardiac function without insertion of intravascular equipment into the central circulation.Acute occlusion of a peripheral blood vessel resulting from intravascular migration of material. Examples of embolic material include thrombus, fat, bone marrow, air, and amniotic fluid.LSensory or motor loss of peripheral nerve function due to a traumatic event."A time period after the procedure.%A time period prior to the procedure.EThe degree of urgency in which a medical procedure must be performed.Flow in the opposite direction from normal, as the casting up of undigested food or gas from the stomach, or the backward flowing of blood into the heart, or between the chambers of the heart when a valve is incompetent.[A surgical procedure that places something in the body that was previously lost or removed.LPathology involving the main renal arteries or extrarenal arterial branches.;Repeat performance of a surgical procedure or intervention.KThe degree of something undesirable e.g. pain or weather; also, strictness.FTobacco that is inhaled or puffed from a lit cigar, cigarette or pipe.UTobacco that is not smoked but used in another form such as chewing tobacco or snuff.2Narrowing or stricture of a vessel, duct or canal.qA study using magnetic resonance to observe cardiac activity during the administration of pharmacologic stressor.UAn unexpected or dangerous reaction to a substance (e.g., food, environmental agent).A local or general reaction of an organism following contact with a speci<>fic allergen to which it has been previously exposed and to which it has become sensitized.A process by which a health professional provides education, recommendations, or interventions to help clients stop using tobacco products.4A registry of patients awaiting an organ transplant.An acute episode of focal or global neurological dysfunction caused by presumed brain, spinal cord, or retinal vascular injury as a result of hemorrhage or infarction but with insufficient information to allow categorization as ischemic or hemorrhagic.Upper Limit of VulnerabilityStimulus strength above which electrical stimulation from a cardiac device cannot induce ventricular fibrillation even when the stimulus occurs during the vulnerable period of the cardiac cycle.%Partial or total occlusion of a vein.HypersensitivityArterial Access ClosurePalliative Care Heart BlockCoronary Vessel LesionCoronary Reperfusion ProcedureVentricular LeadCoronary Culprit LesionMedical Device DeploymentCoronary AngiographyCardiac Electrophysiology StudyCardiac Stress Test&Implantable Cardioverter-defibrillatorCardiac Ischemic Risk ScoreLead DislodgmentCardiac Lead Function IndicatorPerforation due to LeadIn Situ Lead Status Non-Invasive Cardiac Stress Test Triage StatusRepeated Surgical ProcedureSmoking TobaccoTobacco Cessation CounselingCerebrovascular AccidentA procedure that uses high-frequency sound waves (ultrasound) to create an image of the heart under conditions such as exercise, pharmacologic agents or pacing intended to elicit signs and symptoms of myocardial ischemia.C102624C18226C102667C102702C102703C102704C102710C102717C88023C85540C102720C102721C102727Direct Observation TherapyDisease Outcome"Microbial Identification CertaintyReason for Treatment!Reason for Treatment Interruption!Reason Treatment Not AdministeredSite of Directed Therapy#Supporting Evidence for RetreatmentSusceptibility Result CategorySusceptibility TestTreatment EpisodeTreatment Failure ReasonVaccination Evidence SourceDOTcThe therapy is dispensed and consumed under the direct supervision of personnel at a clinical site.A measurable result or effect of treatment on a disease. Examples of outcomes include decreased pain, reduced tumor size, or worsening of disease.tA qualification that describes the degree of certainty of the correctness of a microbial identification test result.*The reason the treatment was administered.6The reason the drug or therapy was temporarily ceased..The reason the treatment was not administered.The physical location at which the medication or therapy was observed, by the healthcare provider, as being taken by the subject.@Clinical evidence to support reason for re-treatment of disease.MSRESCAT;A classification of the finding from a susceptibility test.aA test done to determine whether the growth of specific bacteria is inhibited by a specific drug.An indication of whether this is the individual's first time being treated for a disease or that they are receiving a subsequent treatment.JThe reason the drug or therapy was unsuccessful in treating the condition.ASource of information regarding the subject's vaccination status.Directly Observed Therapy!Site of Directly Observed Therapy+Microbiology Susceptibility Result CategoryMicrobial Susceptibility TestTreatment Episode IndicatorExercise Stress TestkMedical device that increases myocardial oxygen perfusion while at the same time increasing cardiac output.BBD HO{ 1R SVLXZ\^Jcehk;^lJn qe ,tu(w0zC{W@!aN{9   ":pl4c/ޞ`$0k o: ֢X$t£D fĪ" ?d[z C>xK6M ccB f2ɀ *^  dMbP?_*+%,&ffffff?'ffffff?(?)?",B333333?333333?en&<3U} $} I>*c@,)@U@2 @ @(@@@ E@ , , , ,,,,,,,,,,,,,,,,,,, tu Q Q R S T S T S U V W X T S U V U S LP NM OL KK KK KK KK KK KK KK KK KK KK KK KK KK KK KK KK KK KK KKDl ,!,",#,$,%,&,',(,), KK !KK "KK #KK $KK %KK &KK 'KK (KK )MMTPH0(  >@P b(b(3ggD f2ɀ (%5EZU*eg  dMbP?_*+%&ffffff?'ffffff?(?)?M \\corp-fs01\HP LaserJet 9040 P@5C odXXLetterDINU"h,7hSMTJXHP LaserJet 9040 PCL 6InputBinFORMSOURCERESDLLUniresDLLHPDocUISUITrueResolution600dpiFastResTrueOrientationPORTRAITHPOrientRotate180FalseDuplexNONEHPDuplicateJobNameOverrideSWFWPaperSizeLETTEREdgeToEdgeFalseMediaTypeAutoAlternateLetterHeadFalseHPNUseDiffFirstPageChoiceTRUEHPPageExceptionsFileHPZPE4wmHPPageExceptionsInterfaceShowPageExceptionsHPPageExceptionsLowEndHPPageExceptionsLowEndVerHPPageExceptionsCoverInsertionCollateONOutputBinAutoStaplingNoneHPStaplingOpposedFalseEconomodeFalseTextAsBlackFalseTTAsBitmapsSettingTTModeOutlinePrintQualityGroupPQGroup_1HPLpiSelectionNoneHPColorModeMONOCHROME_MODEHPPDLTypePDL_PCL6HPPJLEncodingUTF8HPJobAccountingHPJOBACCT_JOBACNTHPBornOnDateHPBODHPContentOrientationHPContentOrientation_OptionHPXMLFileUsedhpc90506.xmlHPPCL6PassThroughTrueJRConstraintsJRCHDPartialJRHDInstalledJRHDOffJRHDNotInstalledJRHDOffHPDocPropResourceDatahpzhl4wm.cabHPSmartDuplexSinglePageJobTrueHPSmartDuplexOddPageJobTrueHPConsumerCustomPaperTrueHPEnableRAWSpoolingTruePSAlignmentFileHPZLS4wmPSServices_DeviceandSuppliesStatusTRUEHPSmartHub_OnlinediagnostictoolsTRUEHPSmartHub_SupportandtroubleshootingTRUEHPSmartHub_ProductmanualsTRUEHPSmartHub_CheckfordriverupdatesTRUEHPSmartHubInet_SID_263_BID_276_HID_265PSServicesOptionPrnStat_SID_242_BID_270_HID_15521HPPreAnalysisTrueHPPaperSizeALMConstraintsENV_10HPMediaTypeDuplexConstraintsCARDSTOCKHPJobAccWoPinTrue,IUPHdLetter o [none] [none]Arial4Pd?<Automatic>R 44General Everyday PrintingdMicrosoft Office ExcelDomain Users;BI-HIS_TS;mesh-group;MP-IV-700;MSD-HQ;MSD;NIH_Global;MESH Group;MSD GroupCG<EXCEL.EXEC:\Program Files\Microsoft Office\Office12\EXCEL.EXEIPACDRWDSGATCAPI;F4E8Q;Ki݅&E%9xPPBHAERP"dXX333333?333333?&<3U} $ g}  g} g} $g} $g} I7g} $g} $ g@@      _ ` a ` ` ` ` b YZ [ Z Z Z Z \ c ]^ ] c!c c" c! c# ]^ ] c$c c% c$ c& ]^ ] c'c c( c' c) ]^ ] c*c c+ c* c, ]^ ] c-c c. c- c/ ]^ ] c0c c1 c0 c2 ]^ ] c3c c4 c3 c5 ] ^ ] c6 c c7 c6 c8 ] ^ ] c9 c c: c9 c; ] ^ ] c< c c= c< c> ] ^ ] c? 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