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AgendaNatural Products and Biomedical ScienceNatcher Auditorium, Natcher Conference Center04/29/2009 - 04/29/2009Symposium on natural products: an unparalleled source of drug leads and mechanistic probes Agenda8:00 - 8:15 AM Introduction
John Schwab, National Institute of General Medical Sciences (NIGMS)
8:15 - 8:45 AM Perspectives in Industrial Natural Products Research
Frank Petersen, Novartis Institutes for Biomedical Research
8:45 - 9:15 AM The Microtubule Cytoskeleton as a Target for Natural Products
Susan Band Horwitz, Albert Einstein College of Medicine of Yeshiva University
9:15 - 9:45 AM Modified Natural Products as Tubulin-Binding Anticancer Agents
David Kingston, Virginia Polytechnic Institute and State University
9:45 – 10:00 AM BREAK
10:00 - 10:30 AM Mining the Information-Rich Content of Natural Products for Biology and Drug Discovery
Daniel Romo, Texas A&M University
10:30 – 11:00 AM Expanding Natural Product Chemical Diversity With Antibiotic Resistance and Modifying Enzymes
Gerry Wright, McMaster University
11:00 – 11:30 AM Genome Mining for Novel Lantibiotics
Wilfred van der Donk, University of Illinois at Urbana–Champaign
11:30 – 12:00 PM The Deep Ocean as a Resource for Medically Important Natural Products
William Fenical, University of California, San Diego
12:00 - 1:00 PM LUNCH (on your own)
1:00 – 1:30 PM Insights From Multilateral Symbioses of Insects, Fungi, and Bacteria
Jon Clardy, Harvard Medical School
1:30 – 2:00 PM Enantioselective Total Synthesis and Absolute Configuration of (-)-Actinophyllic Acid
Larry Overman, University of California, Irvine
2:00 – 2:30 PM Progress in the Development of Neuroprotective Immunophilin Ligands
Guy Carter, Wyeth Pharmaceuticals
2:30 – 3:00 PM Chemical Ecology Leads for Drug Discovery
Julia Kubanek, Georgia Institute of Technology
3:00 – 3:15 PM BREAK
3:15 – 3:45 PM Natural Products and Synthetic Catalysts
Scott Miller, Yale University
3:45 – 4:15 PM Targeting Symbiont-Rich Sponges as a Source of Anti-Infectives
Carole Bewley, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
4:15 – 4:45 PM Drugs for Bad Bugs: Scientific Challenges of Antibacterial Discovery
David Pompliano, Sanderling Consulting LLC, BioLeap LLC
4:45 – 5:15 PM Nonribosomal and Ribosomal Biosynthetic Strategies
Christopher Walsh, Harvard Medical School
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