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National Institute of General Medical Sciences (NIGMS) and National Cancer Institute (NCI) of the National Institutes of Health (NIH)
 

Users publications resulted from work at the GM/CA @ APS beamlines

(as of June 12, 2012)

  1. Zhou, J., Lancaster, L., Trakhanov, S., and Noller, H. F. (2012) Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosome, RNA 18, 230-240.
  2. Zhang, L., Lu, X., Lu, J., Liang, H., Dai, Q., Xu, G. L., Luo, C., Jiang, H., and He, C. (2012) Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA, Nat Chem Biol.
  3. Yoon, S. I., Kurnasov, O., Natarajan, V., Hong, M., Gudkov, A. V., Osterman, A. L., and Wilson, I. A. (2012) Structural basis of TLR5-flagellin recognition and signaling, Science 335, 859-864.
  4. Xu, R., McBride, R., Nycholat, C. M., Paulson, J. C., and Wilson, I. A. (2012) Structural characterization of the hemagglutinin receptor specificity from the 2009 H1N1 influenza pandemic, J Virol 86, 982-990.
  5. Wu, H., Wacker, D., Mileni, M., Katritch, V., Han, G. W., Vardy, E., Liu, W., Thompson, A. A., Huang, X. P., Carroll, F. I., Mascarella, S. W., Westkaemper, R. B., Mosier, P. D., Roth, B. L., Cherezov, V., and Stevens, R. C. (2012) Structure of the human kappa-opioid receptor in complex with JDTic, Nature.
  6. Wiener, R., Zhang, X., Wang, T., and Wolberger, C. (2012) The mechanism of OTUB1-mediated inhibition of ubiquitination, Nature 483, 618-622.
  7. Thompson, A. A., Liu, W., Chun, E., Katritch, V., Wu, H., Vardy, E., Huang, X. P., Trapella, C., Guerrini, R., Calo, G., Roth, B. L., Cherezov, V., and Stevens, R. C. (2012) Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic, Nature 485, 395-399.
  8. Symersky, J., Pagadala, V., Osowski, D., Krah, A., Meier, T., Faraldo-Gomez, J. D., and Mueller, D. M. (2012) Structure of the c(10) ring of the yeast mitochondrial ATP synthase in the open conformation, Nat Struct Mol Biol 19, 485-491.
  9. Sun, S., Gao, S., Kondabagil, K., Xiang, Y., Rossmann, M. G., and Rao, V. B. (2012) Structure and function of the small terminase component of the DNA packaging machine in T4-like bacteriophages, Proc Natl Acad Sci U S A 109, 817-822.
  10. Snell, G. (2012) X-ray sources and high-throughput data collection methods, Methods Mol Biol 841, 93-141.
  11. Rahman, M. N., Vlahakis, J. Z., Vukomanovic, D., Lee, W., Szarek, W. A., Nakatsu, K., and Jia, Z. (2012) A novel, "double-clamp" binding mode for human heme oxygenase-1 inhibition, PLoS One 7, e29514.
  12. Pavlovsky, A. G., Liu, X., Faehnle, C. R., Potente, N., and Viola, R. E. (2012) Structural characterization of inhibitors with selectivity against members of a homologous enzyme family, Chem Biol Drug Des 79, 128-136.
  13. Padayatti, P., Palczewska, G., Sun, W., Palczewski, K., and Salom, D. (2012) Imaging of protein crystals with two-photon microscopy, Biochemistry 51, 1625-1637.
  14. Obiero, J., Walker, J. R., and Dhe-Paganon, S. (2012) Fold of the conserved DTC domain in deltex proteins, Proteins 80, 1495-1499.
  15. Noinaj, N., Easley, N. C., Oke, M., Mizuno, N., Gumbart, J., Boura, E., Steere, A. N., Zak, O., Aisen, P., Tajkhorshid, E., Evans, R. W., Gorringe, A. R., Mason, A. B., Steven, A. C., and Buchanan, S. K. (2012) Structural basis for iron piracy by pathogenic Neisseria, Nature.
  16. Nichols, D. A., Jaishankar, P., Larson, W., Smith, E., Liu, G., Beyrouthy, R., Bonnet, R., Renslo, A. R., and Chen, Y. (2012) Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A beta-Lactamase, J Med Chem.
  17. Nemerow, G. R., Stewart, P. L., and Reddy, V. S. (2012) Structure of human adenovirus, Curr Opin Virol 2, 115-121.
  18. Mu, R., Dussupt, V., Jiang, J., Sette, P., Rudd, V., Chuenchor, W., Bello, N. F., Bouamr, F., and Xiao, T. S. (2012) Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B, Structure.
  19. Mosser, R., Reddy, M. C., Bruning, J. B., Sacchettini, J. C., and Reinhart, G. D. (2012) Structure of the Apo Form of Bacillus stearothermophilus Phosphofructokinase, Biochemistry 51, 769-775.
  20. McElroy, C. A., Holland, P. J., Zhao, P., Lim, J. M., Wells, L., Eisenstein, E., and Walsh, S. T. (2012) Structural reorganization of the interleukin-7 signaling complex, Proc Natl Acad Sci U S A 109, 2503-2508.
  21. Manglik, A., Kruse, A. C., Kobilka, T. S., Thian, F. S., Mathiesen, J. M., Sunahara, R. K., Pardo, L., Weis, W. I., Kobilka, B. K., and Granier, S. (2012) Crystal structure of the micro-opioid receptor bound to a morphinan antagonist, Nature 485, 321-326.
  22. Liao, J., Li, H., Zeng, W., Sauer, D. B., Belmares, R., and Jiang, Y. (2012) Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger, Science 335, 686-690.
  23. Li, M., Shandilya, S. M., Carpenter, M. A., Rathore, A., Brown, W. L., Perkins, A. L., Harki, D. A., Solberg, J., Hook, D. J., Pandey, K. K., Parniak, M. A., Johnson, J. R., Krogan, N. J., Somasundaran, M., Ali, A., Schiffer, C. A., and Harris, R. S. (2012) First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G, ACS Chem Biol.
  24. Kruse, A. C., Hu, J., Pan, A. C., Arlow, D. H., Rosenbaum, D. M., Rosemond, E., Green, H. F., Liu, T., Chae, P. S., Dror, R. O., Shaw, D. E., Weis, W. I., Wess, J., and Kobilka, B. K. (2012) Structure and dynamics of the M3 muscarinic acetylcholine receptor, Nature 482, 552-556.
  25. Khare, R., Reddy, V. S., Nemerow, G. R., and Barry, M. A. (2012) Identification of adenovirus serotype 5 hexon regions that interact with scavenger receptors, J Virol 86, 2293-2301.
  26. Jin, T., Perry, A., Jiang, J., Smith, P., Curry, J. A., Unterholzner, L., Jiang, Z., Horvath, G., Rathinam, V. A., Johnstone, R. W., Hornung, V., Latz, E., Bowie, A. G., Fitzgerald, K. A., and Xiao, T. S. (2012) Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor, Immunity.
  27. Hanson, M. A., Roth, C. B., Jo, E., Griffith, M. T., Scott, F. L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S. M., Schuerer, S. C., Sanna, M. G., Han, G. W., Kuhn, P., Rosen, H., and Stevens, R. C. (2012) Crystal structure of a lipid G protein-coupled receptor, Science 335, 851-855.
  28. Haga, K., Kruse, A. C., Asada, H., Yurugi-Kobayashi, T., Shiroishi, M., Zhang, C., Weis, W. I., Okada, T., Kobilka, B. K., Haga, T., and Kobayashi, T. (2012) Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist, Nature 482, 547-551.
  29. Gupta, S., Gellert, M., and Yang, W. (2012) Mechanism of mismatch recognition revealed by human MutSbeta bound to unpaired DNA loops, Nat Struct Mol Biol 19, 72-78.
  30. Granier, S., Manglik, A., Kruse, A. C., Kobilka, T. S., Thian, F. S., Weis, W. I., and Kobilka, B. K. (2012) Structure of the delta-opioid receptor bound to naltrindole, Nature 485, 400-404.
  31. Gorny, M. K., Pan, R., Williams, C., Wang, X. H., Volsky, B., O'Neal, T., Spurrier, B., Sampson, J. M., Li, L., Seaman, M. S., Kong, X. P., and Zolla-Pazner, S. (2012) Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals, Virology 427, 198-207.
  32. Feng, M., Jensen, L. M., Yukl, E. T., Wei, X., Liu, A., Wilmot, C. M., and Davidson, V. L. (2012) Proline 107 Is a Major Determinant in Maintaining the Structure of the Distal Pocket and Reactivity of the High-Spin Heme of MauG, Biochemistry.
  33. Dessanti, P., Zhang, Y., Allegrini, S., Tozzi, M. G., Sgarrella, F., and Ealick, S. E. (2012) Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase, Acta Crystallogr D Biol Crystallogr 68, 239-248.
  34. Dassama, L. M., Boal, A. K., Krebs, C., Rosenzweig, A. C., and Bollinger, J. M. (2012) Evidence That the beta Subunit of Chlamydia trachomatis Ribonucleotide Reductase Is Active with the Manganese Ion of Its Manganese(IV)/Iron(III) Cofactor in Site 1, J Am Chem Soc 134, 2520-2523.
  35. Chen, C., Gorlatova, N., and Herzberg, O. (2012) Pliable DNA conformation of response elements bound to transcription factor P63, J Biol Chem.
  36. Brohawn, S. G., del Marmol, J., and MacKinnon, R. (2012) Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel, Science 335, 436-441.
  37. Bieniossek, C., Imasaki, T., Takagi, Y., and Berger, I. (2012) MultiBac: expanding the research toolbox for multiprotein complexes, Trends Biochem Sci 37, 49-57.
  38. Bailey, L. J., Acheson, J. F., McCoy, J. G., Elsen, N. L., Phillips, G. N., and Fox, B. G. (2012) Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase, Biochemistry 51, 1101-1113.
  39. Avvakumov, G. V., Walker, J. R., Xue, S., Allali-Hassani, A., Asinas, A., Nair, U. B., Fang, X., Zuo, X., Wang, Y. X., Wilkinson, K. D., and Dhe-Paganon, S. (2012) Two ZnF-UBP domains in isopeptidase T (USP5), Biochemistry 51, 1188-1198.
  40. Aryal, B. P., Brugarolas, P., and He, C. (2012) Binding of ReO4(-) with an engineered MoO4(2-)-binding protein: towards a new approach in radiopharmaceutical applications, J Biol Inorg Chem 17, 97-106.
  41. Zhu, J., Korostelev, A., Costantino, D. A., Donohue, J. P., Noller, H. F., and Kieft, J. S. (2011) Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome, Proc Natl Acad Sci U S A 108, 1839-1844.
  42. Zhou, X. E., Suino-Powell, K. M., Xu, Y., Chan, C. W., Tanabe, O., Kruse, S. W., Reynolds, R., Engel, J. D., and Xu, H. E. (2011) The orphan nuclear receptor TR4 is a vitamin A-activated nuclear receptor, J Biol Chem 286, 2877-2885.
  43. Yukl, E. T., Goblirsch, B. R., Davidson, V. L., and Wilmot, C. M. (2011) Crystal structures of CO and NO adducts of MauG in complex with pre-methylamine dehydrogenase: implications for the mechanism of dioxygen activation, Biochemistry 50, 2931-2938.
  44. Yoon, S. I., Hong, M., and Wilson, I. A. (2011) An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1, Nat Struct Mol Biol 18, 1028-1035.
  45. Xu, R., and Wilson, I. A. (2011) Structural characterization of an early fusion intermediate of influenza virus hemagglutinin, J Virol 85, 5172-5182.
  46. Xu, F., Wu, H., Katritch, V., Han, G. W., Jacobson, K. A., Gao, Z. G., Cherezov, V., and Stevens, R. C. (2011) Structure of an agonist-bound human A2A adenosine receptor, Science 332, 322-327.
  47. Xiang, Y., and Rossmann, M. G. (2011) Structure of bacteriophage phi 29 head fibers has a supercoiled triple repeating helix-turn-helix motif, P Natl Acad Sci USA 108, 4806-4810.
  48. Wielens, J., Headey, S. J., Deadman, J. J., Rhodes, D. I., Le, G. T., Parker, M. W., Chalmers, D. K., and Scanlon, M. J. (2011) Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1, ChemMedChem 6, 258-261.
  49. Whorton, M. R., and MacKinnon, R. (2011) Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium, Cell 147, 199-208.
  50. Wan, Q., Ahmad, M. F., Fairman, J., Gorzelle, B., de la Fuente, M., Dealwis, C., and Maguire, M. E. (2011) X-Ray Crystallography and Isothermal Titration Calorimetry Studies of the Salmonella Zinc Transporter ZntB, Structure 19, 700-710.
  51. Verdino, P., Witherden, D. A., Ferguson, M. S., Corper, A. L., Schiefner, A., Havran, W. L., and Wilson, I. A. (2011) Molecular insights into gammadelta T cell costimulation by an anti-JAML antibody, Structure 19, 80-89.
  52. Uysal, S., Cuello, L. G., Cortes, D. M., Koide, S., Kossiakoff, A. A., and Perozo, E. (2011) Mechanism of activation gating in the full-length KcsA K+ channel, Proc Natl Acad Sci U S A 108, 11896-11899.
  53. Tsai, C. L., Bridwell-Rabb, J., and Barondeau, D. P. (2011) Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex, Biochemistry 50, 6478-6487.
  54. Torbeev, V. Y., Raghuraman, H., Hamelberg, D., Tonelli, M., Westler, W. M., Perozo, E., and Kent, S. B. H. (2011) Protein conformational dynamics in the mechanism of HIV-1 protease catalysis, P Natl Acad Sci USA 108, 20982-20987.
  55. Tarboush, N. A., Jensen, L. M., Yukl, E. T., Geng, J., Liu, A., Wilmot, C. M., and Davidson, V. L. (2011) Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis, Proc Natl Acad Sci U S A 108, 16956-16961.
  56. Tang, Y., Holbert, M. A., Delgoshaie, N., Wurtele, H., Guillemette, B., Meeth, K., Yuan, H., Drogaris, P., Lee, E. H., Durette, C., Thibault, P., Verreault, A., Cole, P. A., and Marmorstein, R. (2011) Structure of the Rtt109-AcCoA/Vps75 complex and implications for chaperone-mediated histone acetylation, Structure 19, 221-231.
  57. Syeda, F., Fagan, R. L., Wean, M., Avvakumov, G. V., Walker, J. R., Xue, S., Dhe-Paganon, S., and Brenner, C. (2011) The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1, J Biol Chem 286, 15344-15351.
  58. Sun, J., Yang, Y., Wan, K., Mao, N., Yu, T. Y., Lin, Y. C., DeZwaan, D. C., Freeman, B. C., Lin, J. J., Lue, N. F., and Lei, M. (2011) Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha, Cell Res 21, 258-274.
  59. Strushkevich, N., MacKenzie, F., Cherkesova, T., Grabovec, I., Usanov, S., and Park, H. W. (2011) Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system, Proc Natl Acad Sci U S A 108, 10139-10143.
  60. Spurrier, B., Sampson, J. M., Totrov, M., Li, H., O'Neal, T., Williams, C., Robinson, J., Gorny, M. K., Zolla-Pazner, S., and Kong, X. P. (2011) Structural analysis of human and macaque mAbs 2909 and 2.5B: implications for the configuration of the quaternary neutralizing epitope of HIV-1 gp120, Structure 19, 691-699.
  61. Smith, S. M., Rawat, S., Telser, J., Hoffman, B. M., Stemmler, T. L., and Rosenzweig, A. C. (2011) Crystal structure and characterization of particulate methane monooxygenase from Methylocystis species strain M, Biochemistry 50, 10231-10240.
  62. Singh, S., Chang, A., Goff, R. D., Bingman, C. A., Gruschow, S., Sherman, D. H., Phillips, G. N., Jr., and Thorson, J. S. (2011) Structural characterization of the mitomycin 7-O-methyltransferase, Proteins 79, 2181-2188.
  63. Shi, N., Zeng, W., Ye, S., Li, Y., and Jiang, Y. (2011) Crucial points within the pore as determinants of K channel conductance and gating, J Mol Biol 411, 27-35.
  64. Shi, M., Zhu, J., Wang, R., Chen, X., Mi, L., Walz, T., and Springer, T. A. (2011) Latent TGF-beta structure and activation, Nature 474, 343-349.
  65. Shi, C., Geders, T. W., Park, S. W., Wilson, D. J., Boshoff, H. I., Abayomi, O., Barry, C. E., Schnappinger, D., Finzel, B. C., and Aldrich, C. C. (2011) Mechanism-based Inactivation by Aromatization of the Transaminase BioA Involved in Biotin Biosynthesis in Mycobaterium tuberculosis, J Am Chem Soc 133, 18194-18201.
  66. Sette, P., Mu, R., Dussupt, V., Jiang, J., Snyder, G., Smith, P., Xiao, T. S., and Bouamr, F. (2011) The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release, Structure 19, 1485-1495.
  67. Sethe Burgie, E., Bingman, C. A., Makino, S., Wesenberg, G. E., Pan, X., Fox, B. G., and Phillips, G. N., Jr. (2011) Structural architecture of Galdieria sulphuraria DCN1L, Proteins 79, 1329-1336.
  68. Sauer, D. B., Zeng, W., Raghunathan, S., and Jiang, Y. (2011) Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation, Proc Natl Acad Sci U S A 108, 16634-16639.
  69. Ryzhikov, M., Koroleva, O., Postnov, D., Tran, A., and Korolev, S. (2011) Mechanism of RecO recruitment to DNA by single-stranded DNA binding protein, Nucleic Acids Res 39, 6305-6314.
  70. Rosenbaum, D. M., Zhang, C., Lyons, J. A., Holl, R., Aragao, D., Arlow, D. H., Rasmussen, S. G., Choi, H. J., Devree, B. T., Sunahara, R. K., Chae, P. S., Gellman, S. H., Dror, R. O., Shaw, D. E., Weis, W. I., Caffrey, M., Gmeiner, P., and Kobilka, B. K. (2011) Structure and function of an irreversible agonist-beta(2) adrenoceptor complex, Nature 469, 236-240.
  71. Rasmussen, S. G., DeVree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., Mathiesen, J. M., Shah, S. T., Lyons, J. A., Caffrey, M., Gellman, S. H., Steyaert, J., Skiniotis, G., Weis, W. I., Sunahara, R. K., and Kobilka, B. K. (2011) Crystal structure of the beta2 adrenergic receptor-Gs protein complex, Nature 477, 549-555.
  72. Rasmussen, S. G., Choi, H. J., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. S., Kobilka, T. S., Schnapp, A., Konetzki, I., Sunahara, R. K., Gellman, S. H., Pautsch, A., Steyaert, J., Weis, W. I., and Kobilka, B. K. (2011) Structure of a nanobody-stabilized active state of the beta(2) adrenoceptor, Nature 469, 175-180.
  73. Plevka, P., Kaufmann, B., and Rossmann, M. G. (2011) Analysis of phases in the structure determination of an icosahedral virus, Acta Crystallographica Section D-Biological Crystallography 67, 568-577.
  74. Pejchal, R., Doores, K. J., Walker, L. M., Khayat, R., Huang, P. S., Wang, S. K., Stanfield, R. L., Julien, J. P., Ramos, A., Crispin, M., Depetris, R., Katpally, U., Marozsan, A., Cupo, A., Maloveste, S., Liu, Y., McBride, R., Ito, Y., Sanders, R. W., Ogohara, C., Paulson, J. C., Feizi, T., Scanlan, C. N., Wong, C. H., Moore, J. P., Olson, W. C., Ward, A. B., Poignard, P., Schief, W. R., Burton, D. R., and Wilson, I. A. (2011) A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield, Science.
  75. Pai, J. C., Culver, J. A., Drury, J. E., Motani, R. S., Lieberman, R. L., and Maynard, J. A. (2011) Conversion of scFv peptide-binding specificity for crystal chaperone development, Protein Eng Des Sel 24, 419-428.
  76. Oldham, M. L., and Chen, J. (2011) Snapshots of the maltose transporter during ATP hydrolysis, P Natl Acad Sci USA 108, 15152-15156.
  77. Oldham, M. L., and Chen, J. (2011) Crystal structure of the maltose transporter in a pretranslocation intermediate state, Science 332, 1202-1205.
  78. Ojo, K. K., Arakaki, T. L., Napuli, A. J., Inampudi, K. K., Keyloun, K. R., Zhang, L., Hol, W. G., Verlinde, C. L., Merritt, E. A., and Van Voorhis, W. C. (2011) Structure determination of glycogen synthase kinase-3 from Leishmania major and comparative inhibitor structure-activity relationships with Trypanosoma brucei GSK-3, Mol Biochem Parasitol 176, 98-108.
  79. Noinaj, N., Fairman, J. W., and Buchanan, S. K. (2011) The crystal structure of BamB suggests interactions with BamA and its role within the BAM complex, J Mol Biol 407, 248-260.
  80. Noinaj, N., Bosserman, M. A., Schickli, M. A., Piszczek, G., Kharel, M. K., Pahari, P., Buchanan, S. K., and Rohr, J. (2011) The crystal structure and mechanism of an unusual oxidoreductase, GilR, involved in gilvocarcin V biosynthesis, J Biol Chem 286, 23533-23543.
  81. Nelersa, C. M., Schmier, B. J., and Malhotra, A. (2011) Purification and crystallization of Bacillus subtilis NrnA, a novel enzyme involved in nanoRNA degradation, Acta Crystallogr Sect F Struct Biol Cryst Commun 67, 1235-1238.
  82. Nady, N., Lemak, A., Walker, J. R., Avvakumov, G. V., Kareta, M. S., Achour, M., Xue, S., Duan, S., Allali-Hassani, A., Zuo, X., Wang, Y. X., Bronner, C., Chedin, F., Arrowsmith, C. H., and Dhe-Paganon, S. (2011) Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein, J Biol Chem 286, 24300-24311.
  83. Mileni, M., Garfunkle, J., Ezzili, C., Cravatt, B. F., Stevens, R. C., and Boger, D. L. (2011) Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent alpha-ketoheterocycle inhibitor of fatty acid amide hydrolase, J Am Chem Soc 133, 4092-4100.
  84. McLellan, J. S., Pancera, M., Carrico, C., Gorman, J., Julien, J. P., Khayat, R., Louder, R., Pejchal, R., Sastry, M., Dai, K., O'Dell, S., Patel, N., Shahzad-ul-Hussan, S., Yang, Y., Zhang, B., Zhou, T., Zhu, J., Boyington, J. C., Chuang, G. Y., Diwanji, D., Georgiev, I., Kwon, Y. D., Lee, D., Louder, M. K., Moquin, S., Schmidt, S. D., Yang, Z. Y., Bonsignori, M., Crump, J. A., Kapiga, S. H., Sam, N. E., Haynes, B. F., Burton, D. R., Koff, W. C., Walker, L. M., Phogat, S., Wyatt, R., Orwenyo, J., Wang, L. X., Arthos, J., Bewley, C. A., Mascola, J. R., Nabel, G. J., Schief, W. R., Ward, A. B., Wilson, I. A., and Kwong, P. D. (2011) Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9, Nature 480, 336-343.
  85. Macheboeuf, P., Buffalo, C., Fu, C. Y., Zinkernagel, A. S., Cole, J. N., Johnson, J. E., Nizet, V., and Ghosh, P. (2011) Streptococcal M1 protein constructs a pathological host fibrinogen network, Nature 472, 64-68.
  86. Liu, X., Bushnell, D. A., Silva, D. A., Huang, X., and Kornberg, R. D. (2011) Initiation complex structure and promoter proofreading, Science 333, 633-637.
  87. Lin, D. Y., Diao, J., Zhou, D., and Chen, J. (2011) Biochemical and structural studies of a HECT-like ubiquitin ligase from Escherichia coli O157:H7, J Biol Chem 286, 441-449.
  88. Lin, C. C., Baek, K., and Lu, Z. (2011) Apo and InsP-bound crystal structures of the ligand-binding domain of an InsP receptor, Nat Struct Mol Biol 18, 1172-1174.
  89. Li, D., Lee, J., and Caffrey, M. (2011) Crystallizing Membrane Proteins in Lipidic Mesophases. A Host Lipid Screen, Cryst Growth Des 11, 530-537.
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