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Identify Potential Compounds for Inclusion in a Toxicant Screening Program to Identify Potential Selective Toxicants for Control of Asian carp

Principal Investigator: Terry Hubert

Impact of UMESC Science

The results from this toxicant screening process will provide baseline data that may lead to the development of selective fish toxicants that could be used to control invasive fish species. These selective toxicants have the potential to be used by fishery management agencies to control invasive fish species throughout the United Sates.

Introduction

Current toxicants used to control aquatic invasive species are general toxicants with limited to no selectivity (e.g., antimycin and rotenone). Agrichemical and pesticide laboratories create thousands of new chemical compounds yearly. Although toxicity information is generally not available for these new compounds in aquatic organisms, structure activity relationship analysis could identify likely candidates for inclusion in a toxicant screening USGS will develop an inventory of candidate chemicals to include structural and physical characterizations. A database of potential selective fish toxicants will also be developed.  Acute toxicity studies will be initiated to evaluate candidate chemicals and identify selective fish toxicants for further development and registration. 

Objectives

1. Develop a Fish Toxicant Structure-Activity Correlation (FTSAC) database through review of current literature to correlate chemical structures with known modes of toxicity and pathways for elimination.
2. Initiate review of chemical databases and identify contemporary chemicals using FTSAC.