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Outline of this CME Activity

Presentation: Clostridium difficile Infections: Diagnosis, Treatment, and Prevention
Keywords: antibiotic treatment | diagnostic assays | prevention | recurrence | overview
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Overview: Objectives

Presentation: Clostridium difficile Infections: Diagnosis, Treatment, and Prevention
Keywords: diagnostic tests | objectives | prevention | treatment | overview
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Overview: Methods

Presentation: Clostridium difficile Infections: Diagnosis, Treatment, and Prevention
Keywords: analysis | data sources | literature | methods | overview
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Overview: Results for Diagnostic Testing

Presentation: Clostridium difficile Infections: Diagnosis, Treatment, and Prevention
Keywords: overview | diagnostic testing | immunoassays | sensitivity | specificity
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Overview: Results for Treatment of CDI with Standard Antibiotics

Presentation: Clostridium difficile Infections: Diagnosis, Treatment, and Prevention
Keywords: antibiotics | fidaxomicin | results | treatment | vancomycin | overview
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Overview: Results for Nonstandard Interventions to Treat CDI or Reduce the Risk of Recurrence

Presentation: Clostridium difficile Infections: Diagnosis, Treatment, and Prevention
Keywords: antibodies | C. difficile immune whey | fecal transplantation | nonstandard interventions | prebiotics | probiotics | recurrence | overview
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Overview: Results for Prevention

Presentation: Clostridium difficile Infections: Diagnosis, Treatment, and Prevention
Keywords: overview | prevention | antibiotic restriction | environmental interventions | C. difficile infection (CDI) incidence | outbreaks
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Overview: Conclusions

Presentation: Clostridium difficile Infections: Diagnosis, Treatment, and Prevention
Keywords: conclusions | diagnostic assays | patient outcomes | prevention | treatment | overview
Systematic Review Process Overview. This figure presents an overview of the steps in the systematic review process. The first step, the preparation of the topic, requires refining the topic and developing an analytic framework. The second step is to search for and select studies for inclusion, which involves identifying study eligibility criteria, searching for relevant studies, and selecting evidence for inclusion. The third step is to extract data from individual studies. The fourth step is to analyze and synthesize studies, which involves assessing the quality of individual studies, assessing applicability, presenting findings in tables, synthesizing quantitative data, and grading the strength of evidence. The final step is to report the systematic review. This module focuses on the development of analytic frameworks.
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Systematic Review Process Overview

Presentation: Analytic Frameworks
Keywords: systematic review | topic refinement | analytic framework | eligibility criteria | data extraction
Why Use Analytic Frameworks? To provide clinical, biological, or health services underpinnings for the mechanism of action. To clarify implicit assumptions. To identify logical flaws as key questions are developed. To provide a starting point for discussions with key informants. To identify distinct bodies of evidence to be included in the review.
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Why Use Analytic Frameworks?

Presentation: Analytic Frameworks
Keywords: systematic review | Evidence-based Practice Center
This figure presents an overview of the steps in the systematic review process. The first step, the preparation of the topic, requires refining the topic and developing an analytic framework. The second step is to search for and select studies for inclusion, which involves identifying study eligibility criteria, searching for relevant studies, and selecting evidence for inclusion. The third step involves extracting data from individual studies. The fourth step is to analyze and synthesize studies, which involves assessing the quality of individual studies, assessing applicability, presenting findings in tables, synthesizing quantitative data, and grading the strength of evidence. The final step is to report the systematic review. This module focuses on the assessment of applicability.
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Systematic Review Process Overview

Presentation: Assessing Applicability
Keywords: systematic review process
This figure presents an overview of the steps in the systematic review process. The first step, the preparation of the topic, requires refining the topic and developing an analytic framework. The second step is to search for and select studies for inclusion, which involves identifying study eligibility criteria, searching for relevant studies, and selecting evidence for inclusion. The third step involves extracting data from individual studies. The fourth step is to analyze and synthesize studies, which involves assessing the quality of individual studies, assessing applicability, presenting findings in tables, synthesizing quantitative data, and grading the strength of evidence. The final step is to report the systematic review. This module focuses on assessing the quality of individual studies.
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Systematic Review Process Overview

Presentation: Assessing the Quality of Individual Studies
Keywords: systematic review process
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