NCI Resources and Services

Name	Optical Microscopy and Analysis Laboratory (OMAL), Advanced Technology Program, SAIC-Frederick
Expertise	3D optical (confocal and super-resolution) microscopy for imaging of living and fixed cells and tissues; computational resources for visualization and extraction of quantitative information from images
Location	Building 538, Room 104A, NCI-Frederick
Fee Structure

Name	Electron Microscopy Laboratory (EML), Advanced Technology Program, SAIC-Frederick
Expertise	Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) services and expertise in the following specialized areas: immunoelectron microscopy, cryo-electron microscopy, negative stain analysis, ultrastructure analysis and virus particle characterization
Location	Building 538, Room 124, NCI-Frederick
Fee Structure

Name	Small Animal Imaging Program (SAIP), SAIC-Frederick
Expertise	2D and 3D “live” small animal in vivo quantitative imaging techniques for characterizing: mouse models, bio-distribution of molecular imaging probes and therapeutics, monitoring tumors, and drug efficacy studies.
Location	Building 376, Room 225, NCI-Frederick
Fee Structure

Name	CCBB Microscopy Core (Cell and Cancer Biology Branch, CCR)
Expertise	This facility provides a wide range of microscopy and image analysis expertise including live cell imaging, 2D and 3D image acquisition, colocalization of cellular components, and cellular dynamics. Facility personnel provide guidance in experimental design, data acquisition, and analysis.
Location	Building 37, Room 1035, Bethesda
Fee Structure

Name	LCMB Microscopy Core (Laboratory of Cellular and Molecular Biology, CCR)
Expertise	Live Cell Imaging
Location	Building 37, Room 2033B, Bethesda
Fee Structure

Name	LRBGE Fluorescence and Imaging Facility (Laboratory of Receptor Biology and Gene Expression, CCR)
Expertise	This facility provides the NCI intramural research community with access to several different state-of-the-art 3D microscopes, and computers to visualize and process image data. Facility personnel are available for consultation about the design of imaging experiments and/or the analysis of image data. Researchers from other NIH institutes are also welcome to contact us.
Location	Building 41, Room C615, Bethesda
Fee Structure

Name	EIB Microscopy and Digital Imaging Facility (Experimental Immunology Branch, CCR)
Expertise	A wide range of image modes is offered to EIB scientists, from standard immunohistochemistry, through brightfield and wide-field epifluorescence imaging, to highly complex live cell confocal microscopy.
Location	Building 10, Room 4A05, Bethesda
Fee Structure

Name	CCR Confocal Microscopy Core Facility (Laboratory of Experimental Carcinogenesis, CCR)
Expertise	This facility provides the following types of microscopy: multi-labeling, fixed and live, 2 photon, SHG, FRET, FRAP, FLIM, time lapse with heat, humidity, CO 2 and multiple locations, and tiling.
Location	Bethesda Building 37, Room B114
Fee Structure	Note: *We also provide help with experimental design, image analysis and processing*.