Since the NIH Clinical Center opened in 1953, clinical trials have been a key feature of the Intramural Research Program (IRP) portfolio. The program excels in the type of basic research needed to advance biomedical knowledge, providing the very foundation for health research worldwide, as well as the type of clinical research that culminates in cures and therapies.
Additional information on clinical trials conducted through the IRP is also available on this Web site:
Learn more about IRP clinical trials by visiting the NIH Clinical Research Trials and You Web site.
To search for a specific IRP clinical trial, please visit the NIH Clinical Trials Database.
Clinical trials performed in the IRP are distinct. Some have tested research concepts so nascent that no scientific literature existed that could support a traditional grant application. In other cases, the advances arose from years of basic and clinical research only made possible by the equipment, expertise, and research freedom available in the IRP. The following are a few examples of our clinical trials work: