Measles
Rubeola virus
stain of measles
Measles, also called rubeola, is a viral infection best known for its typical skin rash. It is, however, primarily a respiratory infection. The first symptoms are irritability, runny nose, eyes that are red and sensitive to light, hacking cough, and a fever as high as 105 degrees Fahrenheit (40.6 degrees Celsius).

Fever peaks with the appearance of the rash, which typically begins on the forehead, then spreads downward over the face, neck, and body. The child is particularly ill-looking during the first days of the rash. It usually takes about 3 days for the rash to make its way down to the feet. Once the rash appears on the legs and feet, symptoms usually subside within 2 days.

The rash itself looks like large flat red to brown blotches that often flow into one another to completely cover the skin, especially on the face and shoulders. The rash fades in the same order that it appeared, forehead first and feet last. The total time for the rash, from beginning to end, head to toe, is usually about 6 days. As the rash disappears, the healing skin may look brown temporarily, before it sheds in a finely textured peel.

15 Feb 06

Sample Q&A: The Disease

How common is measles in the United States?

Before a vaccine was licensed in1963, there were an estimated 3 to 4 million cases of measles each year. In the years following 1963, the number of measles cases dropped dramatically, with only 1,497 cases in 1983, the lowest annual total reported up to that time.

From 1989 to 1991, 55,622 cases were reported with a total of 123 measles-associated deaths. Half of the cases and deaths were in young children. The most important cause of this epidemic was low immunization rates among preschool-age children. Due to increased immunization efforts after this epidemic, measles cases fell during the 1990s. Only 44 cases were reported in 2002. However, measles is still common in many other countries in the world and can easily be imported, so continued immunization against the disease is still important.

Recommendations of the Advisory Committee on Immunization Practices
National Foundation for Infectious Diseases
In 2000 the US achieved measles elimination however, importation of measles continues and  in 2011 the US reported 222 measles cases and 17 outbreaks. 90% of cases reported last year were associated with importation from other countries.
Information Paper
Package Insert - Vaccine
Package Insert - Vaccine
American National Red Cross
MMQC-12-1407 29 Jun 12
MERCK / M-M-R II (MEASLES, MUMPS, AND  RUBELLA VIRUS VACCINE, LIVE) / VOLUNTARY RECALL
Video: Dr. Swartzberg’s StoryDr. Swartzberg’s Story (3:58) 03 Nov 11
When a patient has measles a chain of cases ensues.
VIS
Vaccine Information Statement (Interim)
Vaccine Information Statement (Interim)