The CCOP network has three components, each of which competes for peer-reviewed funding through a Request for Applications.
- Community Clinical Oncology Program (CCOP) site is a single community organization or a consortium of community hospitals and private practices spanning one or several states. These sites enroll patients onto NCI-approved cancer prevention and control clinical trials as well as cancer treatment trials. Each CCOP affiliates with several Research Bases to have access to a choice of studies. CCOPs are required to accrue more than 100 participants per year. In total, the 47 currently funded CCOPs represent 340 hospitals and 2,900 physicians. Twenty-five CCOPs have been continuously funded since 1983.
- Minority-Based Community Clinical Oncology Program (MB-CCOP) site meets the same requirements as the CCOPs, but must also have a population that is at least 30% minority or underserved. Academic institutions are permitted to be MB-CCOPs. The 16 currently funded MB-CCOPs comprise 55 hospitals and 475 physicians, including 100 minority investigators. Five MB-CCOPs have been continuously funded since 1991.
- CCOP Research Base (RB-CCOP) is a Cooperative Group or NCI-designated Cancer Center that designs, develops, and conducts cancer prevention and control clinical trials. Cooperative Group CCOP Research Bases also provide cancer treatment clinical trials. Eight Cooperative Groups and four Cancer Centers are currently funded as CCOP Research Bases.
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