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Flowchart of the Licensing Process
STEP 1: Select the area of technology that interests you. You can choose from:
- Cancer
- Central Nervous System
- Dental Technology
- Devices/Instrumentation
- Gene Based Therapies
- Infectious Diseases
- Internal Medicine
- Miscellaneous
- Ophthalmology
- Research Materials
STEP 2: Find the specific technology you would like to license. To do so:
- Review the complete listing of abstracts online.
STEP 3: Select the type of license you require
- For more information, read about the various types of licenses available
STEP 4: Fill out a Formal Application for a License
Click here to download the Application for License
A Confidential Disclosure Agreement is required for unpublished Patent Applications
STEP 5: Contact a Licensing and Patenting Manager
- Names and contact information are indicated on each abstract online. A sample abstract is shown below.
- See the latest list of abstracts online
SAMPLE ABSTRACT
Mouse Model for Cerebral Cavernous Malformation, an Inherited Brain Disorder
Description of Invention:
Cerebral Cavernous Malformation (CCM) is a brain disease affecting up to 0.5% of the worldwide population. CCM is characterized by grossly dilated vessels prone to leaking and hemorrhage which result in severe headaches, seizures, and strokes. Inherited forms of the disease are due to mutations in one of three loci, CCM1, CCM2, and CCM3. Prior efforts to develop mice with targeted null mutations in Ccm1, Ccm2, or Ccm3 have been unsuccessful, as such mutations result in embryonic death.
The inventors have developed the first mouse model available for the study of CCM, in which mouse Ccm2 can be conditionally deleted in blood-accessible and endothelial cells, resulting in neurological defects, ataxia, and brain hemorrhages consistent with the human disease. The model was generated through a cross of C57BL/6 Ccm2-floxed mice with C57BL/6 MX-1-Cre mice, which permits inducible ablation by polyinosinic:polycytidylic acid (pIpC).
Inventors:
Ulrich Siebenlist (NIAID) and Yoh-Suke Mukouyama (NHLBI)
Patent Status:
HHS Reference No. E-158-2011/0 — Research Tool
For Additional Information Please Contact:
Tara L. Kirby, Ph.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: 301-435-4426
Fax: 301-402-0220
E-mail: tarak@mail.nih.gov
STEP 6: Submit Your Application
Submit your completed License Application to the Licensing and Patenting Manager responsible for the technology.
- STEP 6.2: If You Want an Exclusive License
Review the model Exclusive Patent License Agreement
OTT will publish a notice of your application in the Federal Register
Other organizations have 30 days to submit comments or apply themselves
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STEP 6.2.A: OTT will notify you of its decision
STEP 7: Negotiate Licensing Terms
If you do not have the Acrobat Reader, please use the link below to download it now.
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