Events Archive
2000
Institute for Genomics & Systems Biology Seminar Series
Gordon Center for Integrative Science W301, The University of Chicago
Latest News
A Comprehensive Nuclear Receptor Network for Breast Cancer Cells
In breast cancer, nuclear receptors (NRs) play a prominent role in governing gene expression, have prognostic utility, and are therapeutic targets. We built a regulatory map for 24 NRs, six chromatin state markers, and 14 breast-cancer-associated transcription factors (TFs) that are expressed in the breast cancer cell line MCF-7.
The inner workings of the circadian clock
Center Investigator Michael Rust and colleagues reveals the biochemical mechanisms that allow the oscillations of the cyanobacterial biological clock to be tuned to changes in the environment while simultaneously maintaining a robust 24-hour period.