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Osteoarthritis Initiative
Updated February 4, 2013
The Osteoarthritis Initiative (OAI) is a multicenter, longitudinal, prospective observational study of knee osteoarthritis (OA). This Initiative is a public-private partnership between the National Institutes of Health (NIH) and private industry that seeks to improve diagnosis and monitoring of osteoarthritis (OA) and foster development of new treatments. The overall aim of the OAI is to develop a public-domain research resource to facilitate the scientific evaluation of biomarkers for osteoarthritis as potential surrogate endpoints for disease onset and progression. For more details and the most recent information on the study, please see the "Osteoarthritis Initiative Updated Summary."
- OA Initiative Updated Summary, January 7, 2013
- OAI Organizational Structure (JPG file 92 KB)
- OAI Worldwide Data Users (JPG file 90 KB)
- News and Press Releases
- Recent Meetings and Activities
- Biospecimens
- Historical Meetings
News and Press Releases
Announcement January 7, 2013: Availability of 60-month images and clinical data from the OAI
Announcement June 24, 2010: Availability of Central Image Assessments of OAI MR Images
Announcement June 15, 2010: Awards of Ancillary and Complementary Research to the Osteoarthritis Initiative
Announcement March 8, 2010: Availability of 36-month images and clinical data from the OAI
Announcement January 13, 2009: Osteoarthritis Initiative Biospecimen Availability
Announcement September 13, 2007: OAI Announces Availability of New Data and Images
Press Release August 1, 2006: Osteoarthritis Initiative Releases First Data
Press Release March 17, 2004: Enrollment Begins for Osteoarthritis Initiative
Press Release August 13, 2002: Sites Chosen for Public-Private Osteoarthritis Initiative
Press Release Public-Private Consortium Launches Osteoarthritis Initiative, July 17, 2001
Recent Meeting and Activities
OAI Biospecimens
- Biospecimens Access Policy and Procedures Statement
- Biospecimens Study Application Guide
- Form Biospecimen Request (PDF version 872 KB)
Historical Items
Ancillary and Complementary Research to the Osteoarthritis Initiative
- Description of Solicitation
- Osteoarthritis, Patient Centered Outcomes and Complementary and Alternative Therapy (CAM)
- Pivotal Osteoarthritis Initiative Magnetic Resonance Imaging Analyses (POMA)
- Hip Morphology and Limb-Specific Risk Factors for Radiographic Hip Osteoarthritis
OAI Evaluation Meeting
June 2, 2008
OA Risk Factor Meeting
October 3, 2008
OA Initiative Prospectus
- August 29, 2000
February 28-29, 2000 Meeting
- Notice of Meeting of The Osteoarthritis Initiative
- Agenda
- Participants Roster
- Meeting Summary
- Appendix A: The U.S. Longitudinal Studies of Osteoarthritis
- Appendix B: The European Longitudinal Studies of OA
- Additional International Osteoarthritis Epidemiology Studies
- Surrogate "White" Paper on Imaging: Summary of January 11, 2000 Imaging Meeting