Trisodium ethylenediaminetetraacetate trihydrate (EDTA)
CASRN: 150-38-9
Formula: C10-H16-N2-O8.3Na
Synonyms/Common Names:
- EDTA
- N,N'-1,2-ETHANEDIYLBIS(N-CARBOXYMETHYL)GLYCINE TRISODIUM SALT (9CI)
- TRISODIUM ETHYLENEDIAMINE TETRACETATE TRIHYDRATE
Known Uses:
Chelating agent; antioxidant in food; used in cosmetics, drugs, rubber, textiles
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C03974)
Completed
- Rats: F344/N; Mice: B6C3F1
- 13-Week (Dosed-Feed)
(C03974)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: 0,4640,21600 PPM/10 PER GROUP.
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C03974)
Report Complete
- TR-011 (NIH Number: 77-811; NTIS Number: PB270938)
(Peer Review Approval 07/25/1977A )
Bioassay of Trisodium Ethylenediaminetetraacetate Trihydrate (EDTA) for Possible Carcinogenicity (CASRN 150-38-9) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: 0,3750,7500 PPM/50 PER GROUP.
- TR-011 (NIH Number: 77-811; NTIS Number: PB270938)
(Peer Review Approval 07/25/1977A )
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(215387)
Completed
- Sister Chromatid Exchange Negative
- Chromosome Aberation Negative
- Mouse Lymphoma
(127205)
Completed
- Citation: McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
- Mice
- Negative
- Salmonella (NCI)
(N-9245)
Completed
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli Environ. Mutagen. Vol. 7 (Suppl 5) (1985) 1-248
- Salmonella
- Salmonella-NCI Negative
- Salmonella
(255190)
Completed
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
- Negative
Web page last updated on January 15, 2013