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416 studies found for:    "cord blood"

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Rank Status Study
1 Suspended Transplantation of Umbilical Cord Blood Following Chemotherapy for Blood Cancers
Conditions: Acute Myeloid Leukemia;   Leukemia, Lymphoblastic, Acute;   Leukemia, Bilineage, Acute;   Leukemia, Myeloid, Chronic
Intervention: Device: Ex vivo expansion of cord blood
2 Recruiting Donor Umbilical Cord Blood Transplant With or Without Ex-Vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes
Conditions: Accelerated Phase Chronic Myelogenous Leukemia;   Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome;   Adult Acute Lymphoblastic Leukemia in Remission;   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Childhood Acute Lymphoblastic Leukemia in Remission;   Childhood Acute Myeloid Leukemia in Remission;   Childhood Chronic Myelogenous Leukemia;   Chronic Phase Chronic Myelogenous Leukemia;   de Novo Myelodysplastic Syndromes;   Previously Treated Myelodysplastic Syndromes;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Excess Blasts in Transformation;   Relapsing Chronic Myelogenous Leukemia;   Secondary Acute Myeloid Leukemia
Interventions: Procedure: ex vivo-expanded cord blood progenitor cell infusion;   Procedure: umbilical cord blood transplantation;   Procedure: double-unit umbilical cord blood transplantation;   Drug: fludarabine phosphate;   Drug: cyclophosphamide;   Radiation: total-body irradiation;   Drug: cyclosporine;   Drug: mycophenolate mofetil
3 Completed
Has Results 		Allogenic Umbilical Cord Blood and Erythropoietin Combination Therapy for Cerebral Palsy
Condition: Cerebral Palsy
Interventions: Biological: Umbilical Cord Blood Infusion;   Drug: Erythropoietin Injection;   Other: Active Rehabilitation;   Other: Placebo Umbilical Cord Blood;   Other: Placebo Erythropoietin
4 Active, not recruiting Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies
Conditions: Accelerated Phase Chronic Myelogenous Leukemia;   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Childhood Acute Lymphoblastic Leukemia in Remission;   Childhood Acute Myeloid Leukemia in Remission;   Childhood Chronic Myelogenous Leukemia;   Childhood Myelodysplastic Syndromes;   Chronic Eosinophilic Leukemia;   Chronic Neutrophilic Leukemia;   Chronic Phase Chronic Myelogenous Leukemia;   de Novo Myelodysplastic Syndromes;   Previously Treated Myelodysplastic Syndromes;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Excess Blasts in Transformation;   Relapsing Chronic Myelogenous Leukemia;   Secondary Myelodysplastic Syndromes
Interventions: Procedure: umbilical cord blood transplantation;   Drug: fludarabine phosphate;   Drug: cyclophosphamide;   Procedure: ex vivo-expanded cord blood progenitor cell infusion;   Radiation: total-body irradiation;   Drug: cyclosporine;   Drug: mycophenolate mofetil;   Other: laboratory biomarker analysis
5 Recruiting A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies
Conditions: Accelerated Phase Chronic Myelogenous Leukemia;   Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome;   Adult Acute Lymphoblastic Leukemia in Remission;   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Adult Nasal Type Extranodal NK/T-cell Lymphoma;   Anaplastic Large Cell Lymphoma;   Burkitt Lymphoma;   Childhood Acute Lymphoblastic Leukemia in Remission;   Childhood Acute Myeloid Leukemia in Remission;   Childhood Chronic Myelogenous Leukemia;   Childhood Diffuse Large Cell Lymphoma;   Childhood Immunoblastic Large Cell Lymphoma;   Childhood Myelodysplastic Syndromes;   Childhood Nasal Type Extranodal NK/T-cell Lymphoma;   Chronic Phase Chronic Myelogenous Leukemia;   Contiguous Stage II Adult Burkitt Lymphoma;   Contiguous Stage II Adult Diffuse Large Cell Lymphoma;   Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma;   Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma;   Contiguous Stage II Adult Lymphoblastic Lymphoma;   Contiguous Stage II Grade 3 Follicular Lymphoma;   Contiguous Stage II Mantle Cell Lymphoma;   de Novo Myelodysplastic Syndromes;   Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue;   Nodal Marginal Zone B-cell Lymphoma;   Noncontiguous Stage II Adult Burkitt Lymphoma;   Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma;   Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma;   Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma;   Noncontiguous Stage II Adult Lymphoblastic Lymphoma;   Noncontiguous Stage II Grade 3 Follicular Lymphoma;   Noncontiguous Stage II Mantle Cell Lymphoma;   Previously Treated Myelodysplastic Syndromes;   Prolymphocytic Leukemia;   Recurrent Adult Burkitt Lymphoma;   Recurrent Adult Diffuse Large Cell Lymphoma;   Recurrent Adult Diffuse Mixed Cell Lymphoma;   Recurrent Adult Grade III Lymphomatoid Granulomatosis;   Recurrent Adult Immunoblastic Large Cell Lymphoma;   Recurrent Adult Lymphoblastic Lymphoma;   Recurrent Childhood Anaplastic Large Cell Lymphoma;   Recurrent Childhood Grade III Lymphomatoid Granulomatosis;   Recurrent Childhood Large Cell Lymphoma;   Recurrent Childhood Lymphoblastic Lymphoma;   Recurrent Grade 1 Follicular Lymphoma;   Recurrent Grade 2 Follicular Lymphoma;   Recurrent Grade 3 Follicular Lymphoma;   Recurrent Mantle Cell Lymphoma;   Recurrent Marginal Zone Lymphoma;   Recurrent Small Lymphocytic Lymphoma;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Excess Blasts in Transformation;   Refractory Chronic Lymphocytic Leukemia;   Refractory Multiple Myeloma;   Secondary Acute Myeloid Leukemia;   Secondary Myelodysplastic Syndromes;   Splenic Marginal Zone Lymphoma;   Stage I Adult Burkitt Lymphoma;   Stage I Adult Diffuse Large Cell Lymphoma;   Stage I Adult Diffuse Mixed Cell Lymphoma;   Stage I Adult Immunoblastic Large Cell Lymphoma;   Stage I Adult Lymphoblastic Lymphoma;   Stage I Childhood Lymphoblastic Lymphoma;   Stage I Grade 3 Follicular Lymphoma;   Stage I Mantle Cell Lymphoma;   Stage II Childhood Lymphoblastic Lymphoma;   Stage III Adult Burkitt Lymphoma;   Stage III Adult Diffuse Large Cell Lymphoma;   Stage III Adult Diffuse Mixed Cell Lymphoma;   Stage III Adult Immunoblastic Large Cell Lymphoma;   Stage III Adult Lymphoblastic Lymphoma;   Stage III Childhood Lymphoblastic Lymphoma;   Stage III Grade 3 Follicular Lymphoma;   Stage III Mantle Cell Lymphoma;   Stage IV Adult Burkitt Lymphoma;   Stage IV Adult Diffuse Large Cell Lymphoma;   Stage IV Adult Diffuse Mixed Cell Lymphoma;   Stage IV Adult Immunoblastic Large Cell Lymphoma;   Stage IV Adult Lymphoblastic Lymphoma;   Stage IV Childhood Lymphoblastic Lymphoma;   Stage IV Grade 3 Follicular Lymphoma;   Stage IV Mantle Cell Lymphoma
Interventions: Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Drug: cyclosporine;   Drug: mycophenolate mofetil;   Other: ex-vivo umbilical cord blood expansion;   Procedure: double-unit umbilical cord blood transplantation;   Procedure: biopsy;   Other: immunologic technique;   Other: diagnostic laboratory biomarker analysis
6 Completed Umbilical Cord Blood Therapy for Cerebral Palsy
Condition: Cerebral Palsy
Interventions: Biological: Umbilical Cord Blood Infusion;   Other: Placebo Umbilical Cord Blood;   Other: Active Rehabilitation
7 Active, not recruiting Randomized Double Cord Blood Transplant Study
Conditions: Leukemia, Lymphocytic, Acute;   Leukemia, Myelocytic, Acute;   Leukemia, Myeloid, Chronic;   Lymphoma, Non-Hodgkin
Interventions: Procedure: Expanded allogeneic cord blood (CB);   Procedure: One Unmanipulated and One Expanded Cord Blood Unit;   Drug: Rituxan;   Drug: Melphalan;   Drug: Thiotepa;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Mesna
8 Recruiting Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders
Conditions: Hematological Malignancy;   Bone Marrow Failure Syndrome
Interventions: Drug: Umbilical Cord Blood Transplantation as Treatment of Adult Patients with Hematologic Disorders;   Radiation: Umbilical Cord Blood Transplantation as Treatment of Adult Patients with Hematologic Disorders;   Procedure: Umbilical Cord Blood Transplantation as Treatment of Adult Patients with Hematologic Disorders
9 Completed Centralized Cord Blood Registry to Facilitate Unrelated Cord Blood Transplantation
Conditions: Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Other Hematological Disorders;   Metabolic Storage Diseases
Intervention: Biological: Search individual cord blood banks
10 Suspended FLT-PET Activity Change After Allogeneic Umbilical Cord Blood (UCB) Therapy in Cerebral Palsy
Condition: Cerebral Palsy
Interventions: Biological: Umbilical Cord Blood Infusion;   Other: Active Rehabilitation;   Other: Placebo Umbilical Cord Blood
11 Recruiting Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the NCBP for Unrelated Transplantation
Condition: Infusion Reactions
Intervention: Drug: unlicensed cord blood units
12 Recruiting Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure
Conditions: Hematopoietic Stem Cell Transplantation;   Mesenchymal Stem Cells;   Umbilical Cord Blood;   Graft Failure;   Hematological Diseases
Interventions: Biological: Mesenchymal stem cells;   Biological: Mesenchymal stem cells and cord blood
13 Recruiting The Collection and Storage of Umbilical Cord Blood for Transplantation
Conditions: Cord Blood Stem Cell Transplantation;   Cord Blood Transplantation;   Hematopoietic Stem Cell Transplantation
Intervention:
14 Not yet recruiting Allogeneic Umbilical Cord Blood Therapy for Chronic TBI
Condition: Traumatic Brain Injury
Intervention: Biological: Allogeneic Umbilical Cord Blood
15 Active, not recruiting Umbilical Cord Blood Therapy for Children With Cerebral Palsy
Condition: Cerebral Palsy
Interventions: Procedure: Umbilical Cord Blood Administration;   Other: Active Rehabilitation
16 Completed
Has Results 		Umbilical Cord Blood Infusion to Treat Type 1 Diabetes
Condition: Type 1 Diabetes Mellitus
Interventions: Procedure: Autologous Umbilical Cord Blood Transfusion;   Biological: Cord blood
17 Active, not recruiting Umbilical Cord Blood Therapy for Children With Global Developmental Delay
Condition: Global Developmental Delay
Interventions: Biological: Umbilical Cord Blood administration;   Other: Active Rehabilitation
18 Completed Unrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells
Conditions: MDS;   Anemia, Aplastic;   Inborn Errors of Metabolism;   Congenital Marrow Failure;   Congenital Immunodeficiency Syndrome
Intervention: Biological: ALDHbr Umbilical Cord Blood Cells
19 Recruiting A Randomized Study of Autologous Umbilical Cord Blood Reinfusion in Children With Cerebral Palsy
Conditions: Cerebral Palsy;   CP;   Spastic Cerebral Palsy
Intervention: Biological: Autologous Umbilical Cord Blood or Placebo
20 Withdrawn Infusion of Expanded Cord Blood T Cells
Conditions: Stem Cell Transplantation;   Leukemia;   Lymphoma;   Pediatric Disorders
Interventions: Radiation: Total Body Irradiation (TBI);   Drug: Melphalan;   Drug: Thiotepa;   Drug: Fludarabine;   Drug: Rituximab;   Drug: Etoposide;   Drug: Anti-thymocyte globulin (ATG);   Drug: Mycophenolate Mofetil (MMF);   Drug: Tacrolimus;   Procedure: Cord Blood Infusion;   Drug: G-CSF;   Procedure: Ex vivo expanded T cell Infusion
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† Indicates status has not been verified in more than two years