| | Principal Investigators
| Peter A. Bandettini,
Ph.D. |
|
Dr. Bandettini is Chief of the Section on Functional Imaging Methods in the Laboratory of Brain and Cognition of the Intramural Research Program. He is also the director of the Functional MRI Core Facility, which maintains cutting edge fMRI capability (one 1.5T human scanner, three 3T human scanners and a 7T human scanner) to over 30 fMRI research teams within NIMH and NINDS. Dr. Bandettini received his B.S. in Physics from Marquette University in 1989 and his Ph.D. in Biophysics from the Medical College of Wisconsin in 1994, where he worked on the early development of magnetic resonance imaging of human brain function using blood oxygenation contrast - known as functional MRI (fMRI). While in graduate school, he published one of the first three papers in fMRI in 1992. During his postdoctoral fellowship at the Massachusetts General Hospital, he continued his investigation of methods to increase the interpretability, resolution and applicability of functional MRI techniques. In 1999, he joined NIMH. In 2001, he was awarded the Scientific Director's Merit Award for his efforts in establishing the NIH FMRI core facility. In 2002, he was awarded the Wiley Young Investigator Award at the annual Organization for Human Brain Mapping Meeting. In 2005, he served as president of the Organization for Human Brain Mapping. He is currently the associate editor of the two primary journals in brain mapping: Human Brain Mapping and NeuroImage. Since the start of his career, he has published about 85 papers, 250 abstracts, 16 book chapters and 1 book. He has also presented over 240 invited lectures. His laboratory is currently developing MRI methods to improve the spatial resolution, temporal resolution, sensitivity, interpretability and applicability of functional MRI. |
| Research Interests |
| The research of the Section on Functional Imaging Methods resides directly at the interface of basic neuroscience, functional MRI methods and clinical applications. The general research goals include the development of novel pulse sequences, brain activation paradigms and processing methods so that more detailed, subtle and clinically relevant information may be extracted from fMRI and anatomical data. Specifically, we are extremely interested in 1) understanding and separating the neuronal and physiologic influences on spontaneous oscillations, 2) the continued development, optimization and utilization of multivariate "fMRI decoding" techniques as a complement to more standard mapping techniques, 3) understanding and separating the neuronal and physiologic influences on fMRI signal dynamics such as the post undershoot and dynamic nonlinearity, and 4) optimizing "embedded contrast" pulse sequences which would allow simultaneous extraction and detailed comparison of cerebral blood flow, oxygenation, and volume, with the goal being a method to quantify resting and active blood oxygenation. |
| Representative Selected Recent Publications: |
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Gonzalez-Castillo J, Roopchansingh V, Bandettini P A,
Bodurk J. Physiological noise effects on the flip angle selection
in BOLD fMRI. NeuroImage. 54(4), 2764–2778. 2011.
(View)
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Handwerker D A, Bandettini P. Hemodynamic signals not
predicted? Not so: A comment on Sirotin and Das (2009). NeuroImage. (in
press) 2011. (View)
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Kriegeskorte N, Cusack R, Bandettini P. How does an fMRI voxel
sample the neuronal activity pattern: compact-kernal or complex spatiotemporal
filter? NeuroImage. 49, 1965-1976. 2010. (View)
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Birn R M, Murphy K, Handwerker D A, Bandettini P A. fMRI
in the presence of task-correlated breathing variations. NeuroImage.
47, 1092-1104. 2009. (View)
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Thomas A G, Marrett, Saad Z S, Ruff D A, Martin A, Bandettini
P A.Functional but not structural changes associate with learning:
an exploration of longitudinal voxel based morphometry
(VBM). NeuroImage. 48, 117-125. 2009. (View)
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Kriegeskorte N, Mur M, Ruff D, Kiani R, Bodurka J, Esteky
H, Tanaka K, Bandettini P. Matching categorical object representations
in inferotemporal cortex of man and monkey. Neuron. 60,
1-16. 2008. (View)
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Murphy K, Birn R M, Handwerker D A, Jones T B, Bandettini P A. The
impact of global signal regression on resting state
correlations: are anti-correlated networks introduced? NeuroImage.44,
893-905. 2008. (View)
|
Address:
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Section on Functional Imaging Methods
Laboratory of Brain and Cognition, NIMH
Building 10, Room 1D80
10 Center Drive, MSC 1148
Bethesda, MD 20892-1148 |
| Phone: |
(301) 402-1333 (office) (240) 938-1610 (mobile) |
| Email
Dr. Bandettini |
| Fax: |
(301) 402-1370 |
| Lab
Web Site: |
http://fim.nimh.nih.gov/ |
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