Center for Structural Molecular Biology

An OBER funded User Facility for Neutron-based Analysis of Bio-Molecular Structures and Function at the Oak Ridge National Laboratory

Neutron-based analysis of biomolecular structure, dynamics and function

Neutons for Biology: Structure, Dynamics and Function

Publications from Research Conducted with CSMB

Bio-SANS Publications

  1. W. T. Heller, G. W. Lynn, V. S. Urban, K. Weiss, and D. A. A. Myles, “The bio-SANS Small-angle neutron scattering instrument at Oak Ridge National Laboratory,” Neutron News 19 (2), 22-23 (2008).
  2. M. H. Alkhatib, D. G. Hayes, and V. S. Urban, “Characterization of microemulsion systems formed by a mixed 1,3-dioxolane ethoxylate/octyl glucoside surfactant system,” Journal of Surfactants and Detergents 12, 277-283 (2009).
  3. G. A. Baker and W. T. Heller, “Small-angle neutron scattering studies of model protein denaturation in aqueous solutions of the ionic liquid 1-Butyl-3-methylimidazolium chloride,” Chemical Engineering Journal 147 (1), 6-12 (2009).
  4. M. B. Cardoso, D. Smolensky, W. T. Heller and H. O’Neill, “Insight into the structure of light-harvesting complex II and its stabilization in detergent solution” Journal of Physical Chemistry B 113 (51), 16377–16383 (2009).
  5. G. Luo, Q. Zhang, A. R. Del Castillo, V. Urban and H. O’Neill, “Characterization of sol gel-encapsulated proteins using small-angle neutron scattering” ACS Applied Materials & Interfaces 1 (10), 2262- 2268 (2009).
  6. Cardoso M. B., Smolensky D., Heller W. T., O’Neill H., “Investigation of detergent effects on the solution structure of spinach Light Harvesting Complex II” Journal of Physics: Conference Series 251, 12041 (2010).
  7. Kent M. S., Cheng G., Murton J. K., Carles E. L., Dibble D. C., Zendejas F., Rodriquez M. A., Tran H., Holmes B., Simmons B. A., Knierim B., Auer M., Banuelos J. L., Urquidi J., Hjelm R. P., “Study of enzymatic digestion of cellulose by small angle neutron scattering” Biomacromolecules 11, 357-368 (2010).
  8. He L., Piper A., Meilleur F., Myles D. A. A., Hernandez R., Brown D. T., Heller W. T., “The structure of Sindbis virus produced from vertebrate and invertebrate hosts determined by small-angle neutron scattering” Journal of Virology 84, 5270-5276 (2010).
  9. S. V. Pingali, V. S. Urban, W. T. Heller, J. McGaughey, H. O’Neill, M. Foston, D. A. Myles, A. Ragauskas, and B. R. Evans, “Breakdown of cell wall nanostructure in dilute acid pretreated biomass,” Biomacromolecules 11 (9), 2329-2335 (2010).
  10. Cardoso M. B., Luckarift H. R., Urban V. S., O’Neill H., Johnson G. R., “Protein localization in silica nanospheres derived via biometric mineralization,” Advanced Functional Materials 20, 3031-3038 (2010).
  11. Tang K. H., Urban V. S., Wen J., Xin Y., Blankenship R. E., “SANS investigation of the photosynthetic machinery of Chloroflexus aurantiacus,” Biophysical Journal 99, 2398-2407 (2010).
  12. Pingali S. V., Urban V. S., Heller W. T., McGaughey J., O’Neill H. M., Foston M., Myles D. A., Ragauskas A. J., Evans B. R., “SANS study of cellulose extracted from switchgrass,” Acta Crystallographica D 66, 1189–1193 (2010).
  13. Heller W. T., O’Neill H. M., Zhang Q., Baker G. A., “Characterization of the influence of the ionic liquid 1-Butyl-3-methylimidazolium chloride on the structure and thermal stability of green fluorescent protein,” Journal of Physical Chemistry B 114, 13866-13871 (2010).
  14. Liu X., Abbott N. L., “Characterization of the nanostructure of complexes formed by single- or double- stranded oligonucleotides with a cationic suractant,” Journal of Physical Chemistry B 114, 15554-15564 (2010).
  15. Gomez del Rio J., Hayes D. G., Urban V. S., “Partitioning behavior of an acid-cleavable, 1,3-dioxolane alkyl ethoxylate, surfactant in single and binary surfactant mixtures for 2- and 3-phase microemulsion systems according to ethoxylate head group size,” Journal of Colloid and Interface Science 352, 424-435 (2010).
  16. Heldt C. L., Sorci M., Posada D., Hirsa A., Belfort G., “Detection and reduction of microaggregates in insulin preparations,” Biotechnology and Bioengineering 108, 237-241 (2010).
  17. Cardoso M. B., Smolensky D., Heller W. T., Hong K., O’Neill H., “Supramolecular assembly of biohybrid photoconversion systems,” Energy & Environmental Science 4, 181-188 (2011).
  18. Chaudhuri B. N., Gupta S., Urban V. S., Chance M. R., D’’Mello R., Smith L., Lyons K., Gee J., “A combined global and local approach to elucidate spatial organization of the mycobacterial ParB-parS partition assembly,” Biochemistry 50, 1799-1807 (2011).”
  19. Richter A. G., Dergunov S. A., Ganus B., Thomas Z., Pingali S. V., Urban V., Liu Y., Porcar L., Pinkhassik E., “Scattering studies of hydrophobic monomers in liposomal bilayers: an expanding shell model of monomer distribution,” Langmuir 27, 3792-3797 (2011).”
  20. Lee C. C., Sun Y., Qian S., Huang H. W., “Transmembrane pores formed by human antimicrobial peptide LL-37,” Biophysical Journal 100, 1688-1696 (2011).”
  21. Tang K. H., Zhu L., Urban V. S., Collins A. M., Biswas P., Blankenship R. E., “Temperature and ionic strength effects on the chlorosome light-harvesting antenna complex,” Langmuir 27, 4816-4828 (2011).
  22. Stanley C. B., Perevozchikova T., Berthelier V., “Structural formation of Huntingtin Exon 1 aggregates probed by small-angle neutron scattering,” Biophysical Journal 100, 2504-2512 (2011).
  23. Heldt C. L., Kurouski D., Sorci M., Grafeld E., Lednev I. K., Belfort G., “Isolating toxic insulin amyloid reactive species that lack β-sheets and have wide pH stability,” Biophysical Journal 100, 2792-2800 (2011).
  24. Petridis L., Pingali S. V., Urban V., Heller W. T., O’Neil H. M., Foston M., Ragauskas A., Smith J. C., “Self-similar multiscale structure of lignin revealed by neutron scattering and molecular dynamics simulation,” Physical Review E 83, 61911 (2011).
  25. Qian S., Heller W. T., “Peptide-induced asymmetric distribution of charged lipids in a vesicle bilayer revealed by small-angle neutron scattering,” Journal of Physical Chemistry B 115, 9831-9837 (2011).
  26. Sai Venkatesh Pingali, Hugh M. O’Neill, Joseph McGaughey, Volker S. Urban, Caroline S. Rempe, Loukas Petridis , Jeremy C. Smith , Barbara R. Evans, and William T. Heller, “Small Angle Neutron Scattering Reveals pH-dependent Conformational Changes in Trichoderma reesei Cellobiohydrolase I”, Journal of Biological Chemistry 286, 32801–32809, (2011)
  27. Kukerka N., Nieh M. P., Katsaras J., “Fluid phase lipid areas and bilayer thicknesses of commonly used phosphatidylcholines as a function of temperature,”Biochimica et Biophysica Acta- Biomembranes 1808, 2761-2771 (2011)
  28. S. Tekobo, A. G. Richter, S. A. Dergunov, S. V. Pingali, V. S. Urban, B. Yan, and E. Pinkhassik, “Synthesis, characterization, and controlled aggregation of biotemplated polystyrene nanodisks”, J Nanopart Res (2011) 13, 6427-6437
  29. Kuo-Hsiang Tang and Robert E. Blankenship, “Neutron and light scattering studies of light-harvesting photosynthetic antenna complexes”, Photosynthesis Research, DOI: 10.1007/s11120-011-9665-x
  30. Dmitri Satsoura, Norbert Kûcerka, Sanjeevan Shivakumar, Jeremy Pencer, Corrie Griffiths, Brian Leber, David W. Andrews, John Katsaras, and Cécile Fradin, “Interaction of the full-length BAX protein with biomimetic mitochondrial liposomes: A small-angle neutron scattering and fluorescence study,” BBA–Biomembranes (2012) 1818, 384–401
  31. Marie Z. Markarian, Haifa H. Hariri, Andreas Reisch, Volker S. Urban, and Joseph B. Schlenoff, “A Small-Angle Neutron Scattering Study of the Equilibrium Conformation of Polyelectrolytes in Stoichiometric Saloplastic Polyelectrolyte Complexes” Macromolecules (2012), 45, 1016–1024
  32. A. Luk, N. S. Murthy, W. Wang, R. Rojas, and J. Kohn, “Study of nanoscale structures in hydrated biomaterials using small-angle neutron scattering,” Acta Biomaterialia, In Press, Accepted Manuscript, doi:10.1016/j.actbio.2011.12.026.
  33. He, L. L., Piper, A., Meilleur, F., Hernandez, R., Heller, W. T., Brown, D. T., “Conformational Changes in Sindbis Virus Induced by Decreased pH Revealed by Small-Angle Neutron Scattering,” J. Virol. (2012) 86, 1982-1987