Jun 04
The Epidemiology and Genomics Research Program (EGRP) has initiated a strategic planning effort to develop scientific priorities for cancer epidemiology research in the next decade in the midst of a period of great scientific opportunity and resource constraints. EGRP would like to engage the research community and other stakeholders in a planning effort that will …
Permanent link to this article: http://blog-epi.grants.cancer.gov/2012/06/04/what-scientific-questions-should-cancer-epidemiology-address-in-the-next-decade-to-impact-public-health/
May 24
Cancer epidemiologists and other health researchers have long relied on the Social Security Administration’s (SSA) Death Master File (DMF) data for determining the vital status of participants. Researchers find the DMF helpful in their observational studies and prevention and clinical trials because it is a single, centralized source of information across the 50 states, low …
Permanent link to this article: http://blog-epi.grants.cancer.gov/2012/05/24/could-the-recent-change-in-availability-of-death-master-file-data-affect-your-research/
May 01
Mitochondria play important roles in cellular energy metabolism, free radical generation, and apoptosis, and as a result, mitochondrial variations that affect these functions may contribute to the development and progression of cancer. In most cases, reactive oxygen species and DNA adducts induce mitochondrial mutations. Other agents that may result in mutations include radiation, infectious agents, and …
Permanent link to this article: http://blog-epi.grants.cancer.gov/2012/05/01/a-tale-of-two-genomes-mitochondrial-genomics-and-cancer-risk/
Apr 16
People with chronic conditions, such as diabetes or chronic obstructive pulmonary disease (COPD), spend enough time managing their symptoms and staying healthy. Should they worry that they might be at higher risk of developing cancer as well? Some, but not all, epidemiologic studies have shown that people with some underlying chronic conditions may be at …
Permanent link to this article: http://blog-epi.grants.cancer.gov/2012/04/16/do-patients-with-chronic-diseases-have-a-higher-risk-of-developing-cancer/
Mar 29
Genetic and environmental risk factors contribute to the occurrence of most common cancers (1). Moreover, these relationships with cancer risk are complicated by the fact that the spectrum of risk factors may depend on the specific cancer subtype. For example, different genetic loci are associated with risk of specific breast cancer subtypes (2). Beyond genetic …
Permanent link to this article: http://blog-epi.grants.cancer.gov/2012/03/29/leveraging-existing-biospecimen-resources/
Mar 15
Welcome to the inaugural posting of the “Cancer Epidemiology Matters” blog, published by the National Cancer Institute’s (NCI’s) Epidemiology and Genomics Research Program (EGRP) (1). Our aim is to engage epidemiologists and other scientists, as well as providers, consumers, and policy makers, in helping chart the direction of cancer epidemiology in the 21st century. This …
Permanent link to this article: http://blog-epi.grants.cancer.gov/2012/03/15/stimulating-fresh-thinking-on-21st-century-cancer-epidemiology-2/
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