May 01
Mitochondria play important roles in cellular energy metabolism, free radical generation, and apoptosis, and as a result, mitochondrial variations that affect these functions may contribute to the development and progression of cancer. In most cases, reactive oxygen species and DNA adducts induce mitochondrial mutations. Other agents that may result in mutations include radiation, infectious agents, and …
Permanent link to this article: http://blog-epi.grants.cancer.gov/2012/05/01/a-tale-of-two-genomes-mitochondrial-genomics-and-cancer-risk/
Apr 16
People with chronic conditions, such as diabetes or chronic obstructive pulmonary disease (COPD), spend enough time managing their symptoms and staying healthy. Should they worry that they might be at higher risk of developing cancer as well? Some, but not all, epidemiologic studies have shown that people with some underlying chronic conditions may be at …
Permanent link to this article: http://blog-epi.grants.cancer.gov/2012/04/16/do-patients-with-chronic-diseases-have-a-higher-risk-of-developing-cancer/
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