Early Neurostimulation for Parkinson's Disease
original article

In this 2-year trial involving patients with Parkinson’s disease and early motor complications, subthalamic stimulation plus medical therapy resulted in better quality of life and motor function than medical therapy alone.

  • CME

Related Editorial

Selumetinib and Radioiodine Uptake in Thyroid Cancer
original article

Inhibition of mitogen-activated protein kinase resulted in an increase in expression of the sodium–iodide symporter in 12 of 20 patients, 8 of whom had sufficient uptake to warrant treatment with radioiodine. Five patients had a response, and 3 had stable disease.

perspective Online First
Cholera and Global Sanitation
perspective audio interview
  • Audio Interview

Featured Multimedia

Current Issue: February 14, 2013

Weekly Audio Summary

Browse Past Issues
original articles
Published Online: January 9, 2013
  • Free Full Text
  • Comments
clinical practice
  • CME
  • Full Text Audio
  • Comments
review article
images in clinical medicine
  • Free Full Text
  • Free Full Text
interactive medical case
  • Free Full Text
  • CME
  • Interactive
case records of the massachusetts
general hospital
  • CME

Perspective

Epidemic Influenza -- Responding to the Expected but Unpredictable
Published Online: January 23, 2013
  • Interactive Graphic
The Cure for Cholera -- Improving Access to Safe Water and Sanitation
Published Online: January 9, 2013
  • Free Full Text
  • Audio Interview
Use of Health IT for Higher-Value Critical Care
Published Online: January 30, 2013
  • Free Full Text

Online First

perspective
original article

More Online First Articles

Image Challenge

Image Challenge

What is the diagnosis?

Image of the Week

Pain and Weight Loss

A 44-year-old woman with Crohn’s disease had abdominal distention and feculent vomiting.

Recent Featured Images

Trends

Most Viewed (Last Week)