Bio
Dr. Gross’ research interests include cellular and network neurophysiology, development of multinetwork platforms for rapid parallel assays, modeling of network dynamics, network-network interactions, multichannel recording and life-support technology for cell culture, and cell-electrode coupling and cell adhesion to artificial surfaces.
Education
Postdoctoral training, Experimental Neuropathology Section, Max Planck Institute for Psychiatry, Munich, Germany, 1977
Ph.D., Neurophysiology and Biophysics, Florida State University, 1973
B.S., Engineering Physics, Stevens Institute of Technology, 1962
Courses
BIOL 3800: Animal Physiology
Articles
Novellino, A., Scelfo, B., Palosaari, T., Sobanaski, T., Shafer, T. J., Johnstone, A. F. M., Gross, G. W.,… Whelan, M. (2011). Development of micro-electrode array based tests for neurotoxicity: Assessment of interlaboratory reproducibility with neuroactive chemicals. Frontiers in Neuroengineering, 4(4), 1-14.
Wu, C., Gopal, K. G., Gross, G. W., Lukas, T. J., & Moore, E. J. (2011). An in vitro model for testing drugs to treat tinnitus. European Journal of Pharmacology, 667, 188-194.
Gopal, K. G., Wu, C., Moore, E., & Gross, G. W. (2011). Assessment of styrene oxide neurotoxicity using in vitro auditory cortex networks. Journal of Otolaryngology, DOI: 10.5402/2011/204804.
More Articles
Johnstone, A. F. M., Gross, G. W., Weiss, D. G., Schroedor, O., Gramowski, A., & Shafer, T. J. (2010). Micro-electrode arrays: A physiologically-based neurotoxicity testing platform for the 21st century. NeuroToxicology, 31, 331-350.
Bozym, R. A., Chimienti, F., Frederickson, C. J., Giblin, L. J., Gross, G. W., Korichneva, I., Li, J.,…Thompson, R.B. (2010). Free zinc outside a narrow range is toxic to a variety of cells in vitro. Experimental Biology and Medicine, 235, 741-750.
Meyer, J. M., Wolf, B., & Gross, G. W. (2009). Magnetic stimulation and depression of mammalian networks in primary neuronal cell cultures. IEEE Biomedical Engineering, 56, 1-12.
Ham, M., Bettencourt, L. M., McDaniel, D., & Gross, G. W. (2008). Spontaneous coordinated activity in cultured networks: Analysis of multiple ignition sites, primary circuits, and burst phase delay distributions. Journal of Computational Neuroscience, 24, 346-357. DOI: 10.1007/s10827-007-0059-1
Shafer, T. J., Rijal, S. O., & Gross, G. W. (2008). Complete inhibition of spontaneous activity in neuronal networks in vitro by deltamethryn and permethryn. NeuroToxicology, 29, 203-212.
Keefer, E. W., Botterman, B. R., Romero, M. I., Rossi, A. F., & Gross, G. W. (2008). Carbon nanotube coating improves neuronal recordings. Nature Nanotechnology, 3, 434-439.
Rijal-Oli, S., & Gross, G. W. (2008). Determination of dissociation constants using spontaneous neuronal network activity recorded with microelectrode arrays in vitro. Journal of Neuroscience Methods, 173, 183-192.
Posters/Presentations
Gross, G. W. (2010). High throughput microelectrode array platforms for quantitative pharmacology, toxicology, and drug development using spontaneously active neural tissue. Invited lecture/ Keynote Address at the 3rd IBEC Symposium on Bioengineering and Nanomedicine: Technical University of Catalonia, Barcelona, Spain.
Gross, G. W. (2010). In vitro bioelectronic screening: Rapid toxicity assessments in an era of accelerated chemical and pharmacological compound production. Invited Speaker at the Heinz-Nixdorf-symposium at the Technical University of Munich, BMW Center, Barcelona, Spain.
Gross, G. W. (2010). Validation and effective application of in vitro systems. Invited Speaker at the 39th Neural Interfaces Conference at the Long Beach Convention Center, Long Beach, CA.
More Presentations
Gross, G. W. (2010). Spontaneously active nerve cell networks on microelectrode arrays: Sensitive and reliable platforms for quantitative pharmacology, toxicology, and drug development. Invited Speaker at the Environmental Protection Agency: Region 6 (drinking water section), Dallas, TX.
Gross, G. W. (2009). Neuro-engineering: New insights and applications. Invited Speaker at the IEEE Aerospace & Electronic Systems, Dallas chapter, Dallas, TX.
Gross, G. W. (2009). High throughput microelectrode array platforms for quantitative pharmacology, toxicology, and drug development. Invited Speaker; Keynote Address at the World Congress on Medical Physics and Biomedical Engineering, Munich.
Gross, G. W. (2008). The dynamics of neuronal ensembles: Theory and applications for engineers. Invited Lecture at the Department of Bioengineering: University of Texas at Arlington.
Gross, G. W. (2008). Nerve cell networks on microelectrode arrays: A window to the internal dynamics of neuronal ensembles and a new platform for rapid toxicity screening, pharmacological assays, and drug development. Invited Lecture at the Southern Methodist University: Department of Electrical Engineering, Dallas, TX.
Gross, G. W. (2007). Nerve cell networks on microelectrode arrays: Platforms for investigations of neuronal dynamics underlying information processing. Invited Lecture at the Grand Challenges in Neural Computation: Center for Nonlinear Studies, Los Alamos National Laboratory, Santa Fe, N.M.
Gross, G. W. (2006). Brain tissue on chips: High throughput-platforms für neuropharmakologie und neuroinformatik. Invited Lecture at the Munich Symposia on Medical Electronics: Microelectronics Meets Medicine.
