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Organic Chemical Metrology Group
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Welcome
The Organic Chemical Metrology Group is responsible for developing, critically evaluating, and applying liquid chromatographic, gas chromatographic, and mass spectrometric techniques for the identification and measurement of organic species in a variety of matrices. Efforts are directed toward applications in clinical chemistry, environmental chemistry, food and nutrition, and forensics and homeland security, and include sample types such as tissues and biological fluids, air particulate matter and sediments, foods and dietary supplements, energetic materials, and pure substances (i.e., reference standards). Measurement services are provided through the development of definitive and reference methods, Standard Reference Materials (SRMs), and quality assurance programs. Programs/Projects
SRMs for Organic Contaminants in Human Serum, Milk, and Urine—NIST and the Centers for Disease Control and Prevention (CDC) are collaborating to develop seven new SRMs to meet the expanding needs for the measurement of organic contaminants in human fluids: … SRMs for Contaminants in Air Particulate Matter— In 1997 the U.S. Environmental Protection Agency (EPA) issued new standards for air particulate matter (PM) as part of the national ambient air quality standards, including new regulations for PM … Saw Palmetto Dietary Supplement Standard Reference Materials— Two Standard Reference Materials containing saw palmetto, SRM 3250 Serenoa repens (Fruit) and SRM 3251 Serenoa repens Extract, have been developed as part of the Analytical Chemistry … Multivitamin/Multielement Dietary Supplement SRM— The Analytical Chemistry Division has produced SRM 3280 Multivitamin/Multielement Tablets for use as a control by laboratories making vitamin or element measurements in similar types of dietary … Micronutrients Measurement Quality Assurance Program— The Micronutrients Measurement Quality Assurance Program, coordinated by the Analytical Chemistry Division, supports measurement technology for selected fat- and water-soluble vitamins and … Measurements and Standards for Botanical Dietary Supplements— As part of a multi-year interagency agreement among the National Institute of Standards and Technology (NIST), the National Institutes of Health's Office of Dietary Supplements (NIH/ODS), the … Fatty Acid Methods and Measurements— The Analytical Chemistry Division is working to develop natural-matrix and solution-based SRMs that are characterized for fatty acid composition. The natural-matrix SRMs are intended primarily for … Evaluation of Oleoresin Capsicum (Pepper Spray) Canisters for Chemical Content and Reliability— Aerosol sprays containing oleoresin capsicum, an extract of hot peppers, have been widely used by law enforcement agencies to subdue non-cooperative individuals. Pepper sprays cause incapacitation … Development of NIST Standard Reference Materials for Trace Explosives Detection— As part of a multiyear interagency agreement between NIST and the Office of Standards of the Department of Homeland Security, NIST is developing a series of Standard Reference Materials (SRMs) to … Botanical Oils Containing Omega-3 and Omega-6 Fatty Acids— The Analytical Chemistry Division has developed a collaborative program with the Center for Drug Evaluation and Research (CDER) and the National Institutes of Health's Office of Dietary … Bitter Orange Standard Reference Materials— Three bitter orange-containing Standard Reference Materials have been developed as part of the Analytical Chemistry Division's program to produce SRMs related to dietary supplements. Levels of … Measurement Methods and Standards for Public Safety and Security— Measurements and standards research within the Analytical Chemistry Division related to public safety and security include a diverse group of activities that are driven primarily by the needs of … CCQM Activities in the Organic Analysis Working Group— NIST's Analytical Chemistry Division has participated in over 50 Consultative Committee for Amount of Substance - Metrology in Chemistry (CCQM) Organic Analysis Working Group (OAWG) studies … Metrology and Standards for Canine Olfactory Detection of Explosives— As part of a multi-year interagency agreement between the Office of Standards of the Department of Homeland Security and NIST, NIST is developing measurement tools for and providing compositional … Biodiesel SRM Development—The NIST Analytical Chemistry Division has collaborated with the Brazil National Institute of Metrology, Standardization and Industrial Quality (INMETRO) on the development of the certified … Measurement and Standards to Support Nutrition Labeling— The Analytical Chemistry Division is working to provide food-matrix reference materials to facilitate compliance with nutritional labeling laws, provide traceability for food exports, improve the … Development of Measurements and Standards for Biofuels— With concerns over the limited supply of non-renewable forms of energy, there is growing interest in renewable sources of energy such as biofuels. The change to renewable energy, however, presents … Dietary Supplement Analysis Quality Assurance Program— The National Institute of Standards and Technology (NIST) has established a Dietary Supplement Quality Assurance Program (DSQAP) in collaboration with the National Institutes of Health (NIH) … Novel Stationary Phase Materials in Separation Science Research— Research activities in separation science continue to focus on investigations of the fundamental physical and chemical processes that influence analyte retention in liquid chromatography (LC), as … Molecular Simulation of Stationary Phase Materials in Liquid Chromatography— Molecular simulation models of monomeric and polymeric stationary phases used for liquid chromatography have been employed to investigate the molecular-level structural features that control … Comprehensive Two-Dimensional Gas Chromatography/Time of Flight Mass Spectrometry (GC x GC/TOF-MS)— Although conventional gas chromatography mass spectrometry (GC/MS) provides relatively high efficiency separations, the analysis of some complex, natural-matrix samples may require the use of even … |
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