Chiefs of Mission for Italy
- Hezekiah Gold Rogers (1840-1841)
- Ambrose Baber (1841-1844)
- Robert Wickliffe (1843-)
- Nathaniel Niles (1848-1850)
- William Burnet Kinney (1850-1853)
- Richard Kidder Meade (1853-)
- John Moncure Daniel (1853-)
- John Moncure Daniel (1854-)
- George Perkins Marsh (1861-1882)
- William Waldorf Astor (1882-1885)
- Anthony Michael Keiley (1885-)
- John Bernhard Stallo (1885-1889)
- Albert Gallatin Porter (1889-1892)
- William Potter (1892-1894)
- James J. Van Alen (1893-)
- Isaac Wayne MacVeagh (1893-1897)
- William Franklin Draper (1897-1900)
- Roger Wolcott (1900-)
- George von Lengerke Meyer (1900-1905)
- Henry White (1905-1907)
- Lloyd Carpenter Griscom (1906-1909)
- John G.A. Leishman (1909-1911)
- Thomas James O'Brien (1911-1913)
- Thomas Nelson Page (1913-1919)
- Robert Underwood Johnson (1920-1921)
- Richard Washburn Child (1921-1924)
- Henry Prather Fletcher (1924-1929)
- John Work Garrett (1929-1933)
- Samuel Miller Breckinridge Long (1933-1936)
- William Phillips (1936-1941)
- George Wadsworth (1941-1941)
- Alexander Comstock Kirk (1944-1946)
- James Clement Dunn (1946-1952)
- Ellsworth Bunker (1952-1953)
- Ann Clare (Boothe) Luce (1953-1956)
- James David Zellerbach (1956-1960)
- George Frederick Reinhardt (1961-1968)
- Hugh Gardner Ackley (1968-1969)
- Graham Anderson Martin (1969-1973)
- John Anthony Volpe (1973-1977)
- Richard Newton Gardner (1977-1981)
- Maxwell M. Rabb (1981-1989)
- Peter F. Secchia (1989-1993)
- Reginald Bartholomew (1993-1997)
- Thomas M. Foglietta (1997-2001)
- Melvin Floyd Sembler (2001-2005)
- Ronald Spogli (2005-2009)
- David H. Thorne (2009-)