Chiefs of Mission for Ghana
- Donald Wakeham Lamm (-1957)
- Peter Rutter (-1957)
- Wilson Clark Flake (1957-)
- Francis Henry Russell (1960-1962)
- William Patrick Mahoney (1962-1965)
- Franklin Hall Williams (1965-)
- Thomas Watkins McElhiney (1968-1971)
- Fred Latimer Hadsel (1971-1974)
- Shirley Jane Temple Black (1974-1976)
- Robert Powell Smith (1976-1979)
- Thomas William Macauley Smith (1979-1983)
- Robert Eugene Fritts (1983-1986)
- Stephen R. Lyne (1987-1989)
- Raymond C. Ewing (1989-1992)
- Kenneth Lee Brown (1992-1995)
- Edward P. Brynn (1995-1998)
- Kathryn Dee Robinson (1998-2001)
- Nancy Jo Powell (2001-2002)
- Mary Carlin Yates (2002-2005)
- Pamela E. Bridgewater-Awkward (2005-2008)
- Donald Gene Teitelbaum (2008-)