ABS>Quinalizarin methods are reported for determining boron in U-Zr alloys, uranium oxides, and aluminum base materials. (W.L.H.)

A method was developed for separating beryllium by ascending paper chromatography. The solvent is a mixture of acetone and nitric acid; quinalizarin is used to show the presence of beryllium. This method is now used to determine beryllium in rocks and soils. (auth)

An azo compound obtained by combining chromotropic acid with diazotized H-acid forms with beryllium a blue colored compound which is stable for 16 hours. An aqueous solution of this reagent is more stable than an aqueous solution of quinalizarin. The reagent has a similar sensitivity to quinalizarin (0.2 gamma Be in 5 ml of solution). ...

Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a moderately potent and poorly selective inhibitor of protein kinase CK2, one of the most pleiotropic serine/threonine protein kinases, implicated in neoplasia and in other global diseases. By virtual screening of the MMS (Molecular Modeling Section) database, we have now identified quinalizarin ...

A number of anthraquinones, anthrones and anthraquinone derivatives were evaluated for antiviral activity against human cytomegalovirus (HCMV) as well as for cytotoxicity. Of those compounds evaluated, quinalizarin, emodin, rhein, hypericin, protohypericin, alizarin, emodin bianthrone and emodin anthrone showed antiviral activity against a normal laboratory HCMV strain, ...

Magnesium was found to accumulate in cross bands of myocytes due to myofibrillar degeneration in the context of myocardial lesions and was also detected from contraction bands in injured fibres of duck feather muscles. Relevant findings were based on histochemical detection of magnesium with quinalizarin, magnesone, and titan-yellow. Amassed degenerated myofibrils and injured ...

Investigation of elastic fibres in various human and animal tissues with the reagents quinalizarin, magneson II, and titan yellow for the detection of magnesium revealed striking positive results. After pretreatment of skin and ligamentum flavum with elastase the tests were negative. The results support the supposition that the amount of magnesium in elastic fibres is ...

Boron is separated from Ti by passing a HCl solution of Ti/sup 4+/ through a cation exchanger of the sulfonic acid type. An aliquot of the effluent is complexed with quinalizarin in H/sub 2/SO/sub 4/ and the complex titrated with water to a previously established color. (auth)

Routine procedures of colorimetric determinations in the form of the oxyquinolinate in CCl/sub 4/ are described. The determination of Ge is carried out with phenylfluoron, that of De is made with quinalizarine; Nb is determined in the form of the Nb/sup 5+/ complex compound with thiocyanic acid; TA is determined with pyrogallol in an acid oxalate solution. Minor ...

The effect of chelating agents added to nutrient solutions on plants growing in these solutions was investigated. Chelating chemicals used were: 8-hydroxyquinoline (oxine), sodium diethyldithiocarbamate (carbamate), sodium 1:8 dihydroxynaphthalene 3:6 disulphonate (chromatropic salt), sodium 1-nitroso-2-naphthol 3:6 disulphonate (nitroso-R-salt), tetrahydroxyanthraquinone ...

The formation of a red complex between boron and the quinalizarin reagent was investigated and used as the basis for a simple and sensitive spectrophotometric method for boron in date cultivars. At 620 nm, the absorbance was linear (r = 0.999) over the 0.25-2.5 micrograms/mL concentration range. The molar absorptivity was found to be 2.23 x 10(3) mol-1 cm-1 and the relative ...

Investigation of elastic fibres in various human and animal tissues with the reagents quinalizarin, magneson II, and titan yellow for the detection of magnesium revealed striking positive results. After pretreatment of skin and ligamentum flavum with elastase the tests were negative. The results support the supposition that the amount of magnesium in elastic fibres is ...

Alizarin, Alizarin S, quinizarin and quinalizarin have been compared as acid-base indicators with Bromocresol Green and Methyl Orange as reference indicators. The chromaticity co-ordinates, complementary chromaticity co-ordinates, pK(a) values, transition pH-range, pH of maximum colour change, optimum concentration for titrations and the quality of colour change were ...

An appropriate regulation of the insulin production and secretion in pancreatic ?-cells is necessary for the control of blood glucose homeostasis. The pancreatic duodenal homeobox factor-1 (Pdx-1) is among the various factors and signals which are implicated in the regulation of the insulin synthesis and secretion in the pancreatic ?-cells. Recently, we identified Pdx-1 as a substrate for protein ...

A number of different low molecular weight and volatile compounds have been tested and compared as matrices in 252Cf plasma-desorption mass spectrometry (PDMS) measurements of oligosaccharides. Some heteroaromatic amines (2-aminothiazole and 3-aminopyridine), hydroxyanthraquinones (alizarin and quinalizarin) and phthaleins (fluorescein) proved to be especially suited to ...

A simple, rapid and sensitive method has been worked out for spectrophotometric determination of macro and micro amounts of alumina in ceramic raw materials and finished products, including glasses. The method is based on the extraction of aluminum oxinate into chloroform after masking of titanium with chromotropic acid and of iron with ascorbic acid and 1,10-phenanthroline or ferrocyanide at pH ...

y accepted and an experimental review of the quinalizarine method were performed. The reagent sodium alyzarinsulfonate was tested for the determination of very small amounts of boron. lt has patent advantages over other reagents proposed. The boric acid was extracted by distillation in a closed run as methylboric ester. The wavelength of maximal sensibility 5600 A ...

Amberlite XAD-2 has been functionalized by coupling it to quinalizarin [1,2,5,8-tetrahydroxyanthraquinone] by means of an -N = N- spacer. Elemental analysis, thermogravimetric analysis, and infrared spectra were used to characterize the resulting new polymer matrix. The matrix has been used to preconcentrate Cu(II), Cd(II), Co(II), Pb(II), Zn(II), and Mn(II) before their ...

Magnetically-assisted chemical separation/preconcentration method for the analysis of beryllium from aqueous solutions was developed. According to this method several extractants were coated on certain magnetic microparticles to assist the extraction of beryllium from the aqueous solutions. The influence of different parameters (type and amount of extractant, pH, equilibrium time and ionic ...

A series of fuel rods was compacted by the electromechanical and pneumatic methods with the object of determining boron homogeneity. An attempt was made to correiate the results of chemical analyses for boron with gamma scan measurements of local density variations and sieve analyses of local rod sections for the distribution of fines. Each fuel rod was loaded incrementally with ...

The calcification of rat hypertrophic cartilage slices in vitro is markedly inhibited by preliminary exposure to metachromatic and other basic dyes. The dyes are effective at 10(-3) to 10(-4)M in the absence of calcium and phosphate. This inhibition does not occur at the same low dye concentration if calcium and phosphate are present. Neither ion alone is effective in preventing the inhibition. ...

The calcification of rat hypertrophic cartilage slices in vitro is markedly inhibited by preliminary exposure to metachromatic and other basic dyes. The dyes are effective at 10^�3 to 10^�4 M in the absence of calcium and phosphate. This inhibition does not occur at the same low dye concentration if calcium and phosphate are present. Neither ion ...

Simple and rapid spectrophotometric procedures have been established for quantitation of nefopam hydrochloride (NF) mebevrine hydrochloride (MB) and phenylpropanolamine hydrochloride (PP). The procedures are based on the reaction between the examined drugs (NF, MB and PP) and alizarin (I), alizarin red S (II), alizarin yellow G (III) and quinalizarin (IV) producing ion-pair ...

New spectrophotometric procedures have been established for the quantitation of piroxicam and tenoxicam. The procedures are based on the reaction between the examined drug and alizarin (I), alizarin red S (II), alizarin yellow G (III) or quinalizarin (IV) producing ion-pair complexes which can be measured at the optimum wavelength. The optimization of the reaction conditions ...

Of three enzymes encoded by HIV-reverse transcriptase, protease, and integrase-only the first two have been exploited clinically as inhibitor targets. Efforts to develop inhibitors of purified integrase protein have yielded many compounds, but none with clinical utility. A different source of integration activity for studies in vitro is provided by replication intermediates isolated from ...

The rapid emergence of human immunodeficiency virus (HIV) strains resistant to available drugs implies that effective treatment modalities will require the use of a combination of drugs targeting different sites of the HIV life cycle. Because the virus cannot replicate without integration into a host chromosome, HIV-1 integrase (IN) is an attractive therapeutic target. Thus, an effective IN ...

ABS>Electromechanical and pneumatic compaction methods were utilized in conjunction with various powder loading techniques to produce high density UO/sub 2/ fuel elements containing 0.05 wt% B/sub 4/C additions. Densities of 87 to 88% of theoretical were attained in 10 to 20 min with the electromechanical approach and densities of 88 to 89% of theoretical were achieved in 3 to 5 min ...

In this study the cytotoxic effects of high concentrations (greater than or equal to 1 x 10(-6) M) of estradiol-17 beta (E2), 2-/4-hydroxyestradiol-17 beta (2-/4-OHE2) and 2-/3-/4-methoxyestradiol-17 beta (2-/3-/4-MeOE2) were determined on dividing MCF-7 and HeLa cells. The 2-MeOE2 metabolite followed by 2-OHE2 and E2 (in this order) proved to be extremely toxic to dividing MCF-7 and HeLa cells. ...

A new simple and rapid ultrasound-assisted ionic liquid-based microextraction method was applied to preconcentrate aluminum(III), gallium(III), and indium(III) ions from water samples as a prior step to their simultaneous spectrophotometric determination using least squares support vector machines regression. In the novel procedure, 1-hexyl-3-methylimidazolium hexafluorophosphate [C(6)MIM][PF(6)] ...

A cloud point extraction process using the nonionic surfactant Triton X-114 to extract molybdenum from aqueous solutions was investigated. The method is based on the complexation reaction of Mo(VI) with 1,2,5,8-tetrahydroxyanthracene-9,10-dione (quinalizarine: QA) and micelle-mediated extraction of the complex. The enriched analyte in the surfactant-rich phase was determined ...

Diffuse reflectance spectroscopy (DRS) can be used as a rapid and sensitive method for the quantitative determination of low amounts of aluminum. In this analytical technique, the analyte in samples are extracted onto a solid sorbent matrix loaded with a colorimetric reagent and then quantified directly on the adsorbent surface. Alternatively, colored aluminum complexes formed in solution can also ...

We have demonstrated the use of cavity ring-down spectroscopy (CRDS) as a detector for high performance liquid chromatography (HPLC). For this use, we have designed and implemented a Brewster's angle flow cell such that cavity ring-down spectroscopy can be performed on microliter volumes of liquids. The system exhibits a linear dynamic range of 3 orders of magnitude (30 nM to 30 microM ...

The estrogen responsive human breast cancer MCF-7 cell culture was examined for its response to 2-hydroxyestrone a principal metabolite of estradiol. Addition of 2-hydroxyestrone to the cell cultures in concentration of 10(-9) - 10(-6) M had no effect on cell growth and proliferation because of rapid O-methylation of the catechol estrogen by catechol O-methyltransferase which is highly active in ...

CK2 denotes a pleiotropic, constitutively active protein kinase whose abnormally high level in many cancer cells is held as an example of "non oncogene addiction". A wide spectrum of cell permeable, fairly specific ATP site-directed CK2 inhibitors are currently available which are proving useful to dissect its biological functions and which share the property of inducing apoptosis of cancer cells ...

Tannic acid and several hydroxylated anthraquinone and cinnamic acid derivatives inhibited the mutagenic activity of (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo [a]pyrene (B[a]P 7,8-diol-9,10-epoxide-2), an ultimate mutagenic and carcinogenic metabolite of benzo [a]pyrene. The mutagenic activity of 0.05 nmol of B[a]P 7,8-diol-9,10-epoxide-2 towards strain TA 100 ...

A variety of anthraquinone (anthracene-9,10-dione) derivatives inhibits rat brain Ca(2+)- and phospholipid-activated protein kinase C (PKC) of which the most potent inhibitors are mitoxantrone (1,4-dihydroxy-5,8-bis[2-(hydroxyethylamino)-ethylamino]-9,10- anthracenedione) (IC50 4 microM) and quinalizarin (1,2,5,8-tetrahydroxy-anthraquinone (IC50 4 microM). Anthraquinone ...