Li W#, Tu D#, Li L, Wollert T, Ghirlando R, Brunger A*, Ye Y* Mechanistic insights into active site-associated polyubiquitination by the ubiquitin conjugating enzyme Ube2g2 Proc Natl Acad Sci U S A(106): 3722-3727, 2009. [Full Text/Abstract]
Wang Q, Mora-Hensen H, Weniger M, Perez-Galan P, Wolford C, Hai T, Ron D, Chen W, Trenkle W, Wiestner A*, Ye Y* ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells Proc Natl Acad Sci U S A(106): 2200-2205, 2009. [Full Text/Abstract]
Li L, Soetandyo N, Ye Y The zince finger protein A20 targets TRAF2 to the lysosomes for degradation Biochim Biophys Acta (1793): 346-353, 2009. [Full Text/Abstract]
Wang Q, Li L, Ye Y Inhibition of p97-dependent protein degradation by Eeyarestatin I. J Biol Chem (283): 7445-7454, 2008. [Full Text/Abstract]
Li L, Hailey DW, Soetandyo N, Li W, Lippincott-Schwartz J, Shu HB, Ye Y Localization of A20 to a lysosome-associated compartment and its role in NFkappaB signaling. Biochim Biophys Acta (1783): 1140-1149, 2008. [Full Text/Abstract]
Lu Y, Lv Y, Ye Y, Wang Y, Hong Y, Fortini ME, Zhong Y, Xie Z A role for presenilin in post-stress regulation: effects of presenilin mutations on Ca2 currents in Drosophila. FASEB J, 2007. [Full Text/Abstract]
Li W, Tu D, Brunger AT, Ye Y A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate. Nature(446): 333-337, 2007. [Full Text/Abstract]
Tu D, Li W, Ye Y, Brunger AT Inaugural Article: Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p. Proc Natl Acad Sci U S A(104): 15599-15606, 2007. [Full Text/Abstract]
Ye Y Diverse functions with a common regulator: Ubiquitin takes command of an AAA ATPase. J Struct Biol (156): 29-40, 2006. [Full Text/Abstract]
Seidner GA, Ye Y, Faraday MM, Alvord WG, Fortini ME Modeling clinically heterogeneous presenilin mutations with transgenic Drosophila. Curr Biol (16): 1026-1033, 2006. [Full Text/Abstract]
Wang Q, Li L, Ye Y Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3. J Cell Biol (174): 963-971, 2006. [Full Text/Abstract]
Ye Y, Shibata Y, Kikkert M, van Voorden S, Wiertz E, Rapoport TA Inaugural Article: Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Proc Natl Acad Sci U S A (102): 14132-14138, 2005. [Full Text/Abstract]
Ye Y The role of the ubiquitin-proteasome system in ER quality control. Essays Biochem (41): 99-112, 2005. [Full Text/Abstract]
Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature (429): 841-847, 2004. [Full Text/Abstract]
Ye Y, Meyer HH, Rapoport TA Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J Cell Biol (162): 71-84, 2003. [Full Text/Abstract]
Tsai B#, Ye Y#, Rapoport TA Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat Rev Mol Cell Biol (3): 246-255, 2002. [Full Text/Abstract]
Ye Y, Meyer HH, Rapoport TA The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature (414): 652-656, 2001. [Full Text/Abstract]
Ye Y, Fortini ME Apoptotic activities of wild-type and Alzheimer''s disease-related mutant presenilins in Drosophila melanogaster. J Cell Biol (146): 1351-1364, 1999. [Full Text/Abstract]
Ye Y, Lukinova N, Fortini ME Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants. Nature (398): 525-529, 1999. [Full Text/Abstract]
Ye Y, Fortini ME Characterization of Drosophila Presenilin and its colocalization with Notch during development. Mech Dev (79): 199-211, 1998. [Full Text/Abstract]
# co-first author
* co-corresponding author