1. Tikhonova IG, Sum CS, Neumann S, Thomas CJ, Raaka BM, Costanzi S, Gershengorn MC Bidirectional, Iterative Approach to the Structural Delineation of the Functional "Chemoprint" in GPR40 for Agonist Recognition. J Med Chem(50): 2981-9, 2007. [Full Text/Abstract]
2. Morton RA, Geras-Raaka E, Wilson LM, Raaka BM, Gershengorn MC Endocrine precursor cells from mouse islets are not generated by epithelial-to-mesenchymal transition of mature beta cells. Mol Cell Endocrinol(270): 87-93, 2007. [Full Text/Abstract]
3. Jaschke H, Neumann S, Moore S, Thomas CJ, Colson AO, Costanzi S, Kleinau G, Jiang JK, Paschke R, Raaka BM, Krause G, Gershengorn MC A low molecular weight agonist signals by binding to the transmembrane domain of thyroid-stimulating hormone receptor (TSHR) and luteinizing hormone/chorionic gonadotropin receptor (LHCGR). J Biol Chem(281): 9841-4, 2006. [Full Text/Abstract]
4. Moore S, Jaeschke H, Kleinau G, Neumann S, Costanzi S, Jiang JK, Childress J, Raaka BM, Colson A, Paschke R, Krause G, Thomas CJ, Gershengorn MC Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns. J Med Chem(49): 3888-96, 2006. [Full Text/Abstract]
5. Engel S, Neumann S, Kaur N, Monga V, Jain R, Northup J, Gershengorn MC Low affinity analogs of thyrotropin-releasing hormone are super-agonists. J Biol Chem(281): 13103-9, 2006. [Full Text/Abstract]
6. Wei C, Geras-Raaka E, Marcus-Samuels B, Oron Y, Gershengorn MC Trypsin and thrombin accelerate aggregation of human endocrine pancreas precursor cells. J Cell Physiol(206): 322-8, 2006. [Full Text/Abstract]
7. Jiang JK, Thomas CJ, Neumann S, Lu X, Rice KC, Gershengorn MC 1-(Phenyl)isoquinoline carboxamides: a novel class of subtype selective inhibitors of thyrotropin-releasing hormone (TRH) receptors. Bioorg Med Chem Lett (15): 733-6, 2005. [Full Text/Abstract]
8. Huang W, Osman R, Gershengorn MC Agonist-induced conformational changes in thyrotropin-releasing hormone receptor type I: disulfide cross-linking and molecular modeling approaches. Biochemistry (44): 2419-31, 2005. [Full Text/Abstract]
9. Du D, Raaka BM, Grimberg H, Lupu-Meiri M, Oron Y, Gershengorn MC Carboxyl tail cysteine mutants of the thyrotropin-releasing hormone receptor type 1 exhibit constitutive signaling: role of palmitoylation. Mol Pharmacol(68): 204-9, 2005. [Full Text/Abstract]
10. Gershengorn MC, Hardikar AA, Wei C, Geras-Raaka E, Marcus-Samuels B, Raaka BM Epithelial-to-mesenchymal transition generates proliferative human islet precursor cells. Science (306): 2261-4, 2004. [Full Text/Abstract]