Principal Officers and Chiefs of Mission, by year: 1845

Note: Career Foreign Service appointees are asterisked.

• Wise, Henry Alexander (1806-1876)
  • Envoy Extraordinary and Minister Plenipotentiary, Brazil (1844-1847)
  • Envoy Extraordinary and Minister Plenipotentiary, France (Not commissioned; nomination rejected by the Senate.)
• Bidlack, Benjamin A. (1804-1849)
  • Chargé d'Affaires, Colombia (1845-1849)
• Boulware, William (?-?)
  • Chargé d'Affaires, Two Sicilies (1841-1845)
• Clemson, Thomas Green (1807-1888)
  • Chargé d'Affaires, Belgium (1844-1851)
• Brent, William (1783-1848)
  • Chargé d'Affaires, Argentina (1844-1846)
• Bryan, John Alexander (?-?)
  • Chargé d'Affaires, Peru (1844-1845)
• Buchanan, James (1791-1868)
  • Envoy Extraordinary and Minister Plenipotentiary, Russia (1832-1833)
  • Secretary of State (1845-1849)
  • Envoy Extraordinary and Minister Plenipotentiary, United Kingdom (1853-1856)
• Calhoun, John Caldwell (1782-1850)
  • Secretary of State (1844-1845)
• Carr, Dabney Smith (1802-1854)
  • Minister Resident, Turkey (1843-1849)
• Crump, William Wood (1819-1897)
  • Chargé d'Affaires, Chile (1844-1847)
• Davezac (D'Avezac), Auguste Genevieve Valentin (1780-1851)
  • Chargé d'Affaires, Netherlands (1831-1839)
  • Chargé d'Affaires, Netherlands (1845-1850)
• Cralle, Richard K. (?-?)
  • Chief Clerk (1844-1845)
• Donelson, Andrew Jackson (1799-1871)
  • Chargé d'Affaires, Texas (1844-1845)
  • Envoy Extraordinary and Minister Plenipotentiary, Germany (1846-1849)
  • Envoy Extraordinary and Minister Plenipotentiary, Germany (1848-1849)
• Derrick, William S. (?-1852)
  • Secretary of State ad interim (1843)
  • Chief Clerk (1843-1844)
  • Chief Clerk (1845)
  • Chief Clerk (1847-1848)
  • Chief Clerk (1848-1852)
• Ellis, Vespasian (?-?)
  • Chargé d'Affaires, Venezuela (1844-1845)
• Ellsworth, Henry William (1814-1864)
  • Chargé d'Affaires, Sweden (1845-1861)
• Everett, Alexander Hill (1790-1847)
  • Chargé d'Affaires, Netherlands (1818-1824)
  • Envoy Extraordinary and Minister Plenipotentiary, Spain (1825-1829)
  • Commissioner, China (1845-1847)
• Everett, Edward (1794-1865)
  • Envoy Extraordinary and Minister Plenipotentiary, United Kingdom (1841-1845)
  • Commissioner, China (1843)
  • Secretary of State (1852-1853)
• Hughes, Christopher (1786-1849)
  • Chargé d'Affaires, no se (1819-1825)
  • Chargé d'Affaires, Netherlands (1825-1830)
  • Chargé d'Affaires, Sweden (1830-1841)
  • Chargé d'Affaires, Netherlands (1842-1845)
• Jewett, Albert Gallatin (1802-1885)
  • Chargé d'Affaires, Peru (1845)
• Irving, Washington (1783-1859)
  • Envoy Extraordinary and Minister Plenipotentiary, Spain (1842-1846)
• Irwin, William Wallace (1803-1856)
  • Chargé d'Affaires, Denmark (1843-1847)
• King, William Rufus de Vane (1786-1853)
  • Envoy Extraordinary and Minister Plenipotentiary, France (1844-1846)
• McLane, Louis (1786-1857)
  • Envoy Extraordinary and Minister Plenipotentiary, United Kingdom (1829-1831)
  • Secretary of State (1833-1834)
  • Envoy Extraordinary and Minister Plenipotentiary, United Kingdom (1845-1849)
• Lay, George Washington (1798-1860)
  • Chargé d'Affaires, Sweden (1842-1845)
• Pickett, James Chamberlayne (1793-1872)
  • Chargé d'Affaires, Peru (1838-1845)
• Polk, William Hawkins (1815-1862)
  • Chargé d'Affaires, Two Sicilies (1845-1847)
• Rencher, Abraham (1798-1883)
  • Chargé d'Affaires, Portugal (1843-1847)
• Shields, Benjamin Glover (1808-?)
  • Chargé d'Affaires, Venezuela (1845-1850)
• Slidell, John (1793-1871)
  • Envoy Extraordinary and Minister Plenipotentiary, Mexico (1845)
  • Envoy Extraordinary and Minister Plenipotentiary, Costa Rica (1853)
  • Envoy Extraordinary and Minister Plenipotentiary, El Salvador (1853)
  • Envoy Extraordinary and Minister Plenipotentiary, Guatemala (1853)
  • Envoy Extraordinary and Minister Plenipotentiary, Honduras (1853)
  • Envoy Extraordinary and Minister Plenipotentiary, Nicaragua (1853)
• Stiles, William Henry (1808-1865)
  • Chargé d'Affaires, Austria (1845-1849)
• Todd, Charles Stewart (1791-1871)
  • Envoy Extraordinary and Minister Plenipotentiary, Russia (1841-1846)
• Trist, Nicholas Philip (1800-1874)
  • Chief Clerk (1845-1847)
• Wheaton, Henry (1785-1848)
  • Chargé d'Affaires, Denmark (1827-1835)
  • Chargé d'Affaires, Germany (1835)
  • Envoy Extraordinary and Minister Plenipotentiary, Germany (1837-1846)