Principal Officers and Chiefs of Mission, by year: 1841
Note: Career Foreign Service appointees are asterisked.
- Woodside, Jonathan F. (1799-1845)
- Chargé d'Affaires, Denmark (1835-1841)
- Baber, Ambrose (?-?)
- Chargé d'Affaires, Italy (1841-1844)
- Barrow, Washington (1817-1866)
- Chargé d'Affaires, Portugal (1841-1844)
- Bleecker, Harmanus (1779-1849)
- Chargé d'Affaires, Netherlands (1839-1842)
- Boulware, William (?-?)
- Chargé d'Affaires, Two Sicilies (1841-1845)
- Cambreleng, Churchill Caldom (1786-1862)
- Envoy Extraordinary and Minister Plenipotentiary, Russia (1840-1841)
- Cass, Lewis (1782-1866)
- Envoy Extraordinary and Minister Plenipotentiary, France (1836-1842)
- Secretary of State (1857-1860)
- Ellis, Powhatan (1790-1863)
- Chargé d'Affaires, Mexico (1836)
- Envoy Extraordinary and Minister Plenipotentiary, Mexico (1839-1842)
- Eve, Joseph (?-1843)
- Chargé d'Affaires, Texas (1841-1843)
- Everett, Edward (1794-1865)
- Envoy Extraordinary and Minister Plenipotentiary, United Kingdom (1841-1845)
- Commissioner, China (1843)
- Secretary of State (1852-1853)
- Flood, George H. (?-?)
- Chargé d'Affaires, Texas (1840-1841)
- Forsyth, John (1780-1841)
- Minister Plenipotentiary, Spain (1819-1823)
- Secretary of State (1834-1841)
- Hughes, Christopher (1786-1849)
- Chargé d'Affaires, no se (1819-1825)
- Chargé d'Affaires, Netherlands (1825-1830)
- Chargé d'Affaires, Sweden (1830-1841)
- Chargé d'Affaires, Netherlands (1842-1845)
- Jenifer, Daniel (1791-1855)
- Envoy Extraordinary and Minister Plenipotentiary, Austria (1841-1842)
- Hunter, William (1774-1849)
- Chargé d'Affaires, Brazil (1834-1835)
- Envoy Extraordinary and Minister Plenipotentiary, Brazil (1841-1843)
- Jackson, Isaac Rand (?-1842)
- Chargé d'Affaires, Denmark (1841-1842)
- Kavanagh, Edward (1795-1844)
- Chargé d'Affaires, Portugal (1835-1841)
- Martin, Jacob L. (?-1848)
- Chief Clerk (1840-1841)
- Secretary of State ad interim (1841)
- Chargé d'Affaires, Holy See (1848)
- Maxcy, Virgil (1785-1844)
- Chargé d'Affaires, Belgium (1837-1842)
- Pendleton, John Strother (1802-1868)
- Chargé d'Affaires, Chile (1841-1844)
- Chargé d'Affaires, Argentina (1851-1854)
- Pickett, James Chamberlayne (1793-1872)
- Chargé d'Affaires, Peru (1838-1845)
- Porter, David (1780-1843)
- Chargé d'Affaires, Turkey (1831)
- Minister Resident, Turkey (1839-1843)
- Rogers, Hezekiah Gold (1811-1882)
- Chargé d'Affaires, Italy (1840-1841)
- Semple, James (1798-1866)
- Chargé d'Affaires, Colombia (1837-1842)
- Stevenson, Andrew (1784-1857)
- Envoy Extraordinary and Minister Plenipotentiary, United Kingdom (1836-1841)
- Todd, Charles Stewart (1791-1871)
- Envoy Extraordinary and Minister Plenipotentiary, Russia (1841-1846)
- Vail, Aaron (1796-1878)
- Chargé d'Affaires, United Kingdom (1832-1836)
- Chief Clerk (1838-1840)
- Chargé d'Affaires, Spain (1840-1842)
- Throop, Enos Thompson (1784-1874)
- Chargé d'Affaires, Two Sicilies (1838-1841)
- Webster, Daniel Fletcher (1813-1862)
- Webster, Daniel (1782-1852)
- Secretary of State (1841-1843)
- Secretary of State (1850-1852)
- Wheaton, Henry (1785-1848)
- Chargé d'Affaires, Denmark (1827-1835)
- Chargé d'Affaires, Germany (1835)
- Envoy Extraordinary and Minister Plenipotentiary, Germany (1837-1846)