Talking Glossary of Genetic Terms

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Daphne W. Bell, Ph.D. defines Tumor Suppressor Gene

Tumor Suppressor Gene

A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division. The tumor suppressor protein plays a role in keeping cell division in check. When mutated, a tumor suppressor gene is unable to do its job, and as a result uncontrolled cell growth may occur. This may contribute to the development of a cancer.

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