En EspanolTalking Glossary of Genetic Terms
Christopher P. Austin, M.D. defines Open Reading Frame
Open Reading Frame
An open reading frame is a portion of a DNA molecule that, when translated into amino acids, contains no stop codons. The genetic code reads DNA sequences in groups of three base pairs, which means that a double-stranded DNA molecule can read in any of six possible reading frames--three in the forward direction and three in the reverse. A long open reading frame is likely part of a gene.
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