Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for Adults With Type 2 Diabetes
AHRQ Web Conference on Insulin Analogues Report
February 26, 2009
The prevalence of type 2 diabetes is increasing, more patients are using insulin, and glycemic control has been shown to be beneficial for decreasing the risk of selected long-term complications. As a result, continued scientific evidence evaluating the safety and effectiveness of newer therapies, including the insulin analogues relative to conventional insulin and noninsulin antidiabetic therapies in achieving glycemic control, is vitally needed.
To support informed health care decisions by patients, clinicians, and policymakers and improve the quality, effectiveness, and efficiency of health care to support evidence-based practice, the Agency for Healthcare Research and Quality (AHRQ) has developed a comprehensive, evidence-based review tool for insulin analogues in premixed formulations.
To help pharmacists and other health care professionals use this tool, AHRQ hosted a Web conference titled "Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for Adults With Type 2 Diabetes." This event featured experts from AHRQ as well as a presentation by Rehan Qayyum, M.D., assistant professor of medicine at The Johns Hopkins University School of Medicine and primary investigator for this research. This event:
- Discussed the effectiveness of premixed insulin analogues in achieving optimal glycemic control as compared to insulin regimens.
- Compared the differences in premixed insulin analogues from other commonly used insulin preparations with regard to safety, adverse effects, or adherence.
- Evaluated the effectiveness and safety of the new premixed insulin analogue regimens in individuals on oral antidiabetic agents and individuals with different blood glucose patterns or types of control.
- Discussed practical and effective therapy options for patients with diabetes.
Web Conference
Speakers shared key insights on AHRQ's Effective Health Care Program, the results of the Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for Adults with Type 2 Diabetes report, and how pharmacists can use this report in practice.
Select to access a recording of the Web conference. (Transcript). IMPORTANT: The archived Web conference and transcript contain a course number and access code not applicable to this home-based study. Instead, please refer to the Continuing Education Credit section below.
Note: Due to technical difficulties with the sound quality at the beginning of the Web conference, the presentation has been edited to begin with the first speaker.
Select to access the slide presentation for the Web conference (Powerpoint® slides, 4.58 MB; Text Version).
Note: To ensure that your computer meets the technical requirements to view the Web conference, go to: On24 System Requirements.
Speakers
- Rehan Qayyum, M.D., Principal Investigator at the Evidence-based Practice Center at The Johns Hopkins University.
- Barbara A. Bartman, M.D., M.P.H., Medical Officer in the Center for Outcomes and Evidence at AHRQ.
- Scott Smith, R.Ph., M.S.P.H., Ph.D., Director of the Pharmaceutical Outcomes Research programs at AHRQ's Center for Outcomes and Evidence.
- Carmen Kelly, Pharm.D., R.Ph., Pharmacist Officer in the Center for Outcomes and Evidence at AHRQ.
AHRQ Tools Discussed
Current as of June 2009.
Continuing Education Credit
The American Pharmacists Association (APhA) and Agency for Healthcare Research and Quality have collaborated for the purpose of developing and providing continuing pharmacy education for the activity entitled "Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for Adults With Type 2 Diabetes."
APhA is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. The ACPE Universal Activity Number assigned to the activity by the accredited provider is: 202-999-09-111-H01-P. This activity is approved for 1 contact hour of continuing pharmacy education credit (0.1 CEU). If you have received credit for this course as a live study, you will not be able to receive credit for the home-based study version.
To obtain continuing pharmacy education credit for this activity, participants must participate in the entire activity, and complete the online activity evaluation form and test questions located on www.pharmacist.com/education/. A Statement of Credit will be automatically generated upon achieving these requirements. There is no fee to participate in this activity.
ACPE Activity Type: Knowledge-Based
Instructions to Obtain CE Credit for this Activity:
- Go to www.pharmacist.com/education/.
- Select Online CE Center, and select Quick List.
- Select activity title from list (ACPE Universal Activity Number: 202-999-09-111-H01-P).
- Log in. APhA members, enter your user name and password. Not an APhA member? It is easy to participate! Just click Create one now to open an account. No fee is required to register.
- Once you have completed the online posttest and evaluation form, your Statement of Credit will be accessible immediately.
Initial Release Date: February 26, 2009.
This activity was developed by the American Pharmacists Association and the Agency for Healthcare Research and Quality.
Grievance Policy
Should any attendee of these accredited activities be dissatisfied with the quality of the activity, a request in writing must be submitted to the APhA Education Department within 5 days of the conclusion of the activity.
Disclosure Information
Barbara A. Bartman, M.D., M.P.H., Scott Smith, R.Ph., M.S.P.H., Ph.D., and Carmen Kelly, Pharm.D, R.Ph., have no financial interests or relationships to disclose.
Rehan Qayyum, M.D., received grant support from the Agency for Healthcare Research and Quality (AHRQ) through contract # 290-02-0018.
AHRQ's Office of Communications and Knowledge Transfer Staff, The Lewin Group Project Staff, and APhA's Editorial Staff declare no conflicts of interest or financial interests in any product or service mentioned in this program, including grants, employment, gifts, stock holdings, and honoraria.
Speaker Biosketches
Rehan Qayyum, M.D.
Dr. Qayyum is Assistant Professor of Medicine at The Johns Hopkins University School of Medicine and investigator at the Evidence-based Practice Center at The Johns Hopkins University. His research interests include systematic reviews and meta-analyses of clinical interventions. He was principal investigator of the systematic review of the comparative effectiveness of premixed insulin analogues. Currently, he holds a career development grant sponsored by National Institutes of Health.
Barbara A. Bartman, M.D., M.P.H.
Dr. Bartman is a Medical Officer in the Center for Outcomes and Evidence at AHRQ. She received her M.D. degree from Jefferson Medical College and a Masters of Public Health degree in Epidemiology and Preventive Medicine from the George Washington University School of Medicine and Health Sciences. She completed a residency at the George Washington University Hospital and is board certified in Internal Medicine. She also completed a post-doctoral program in health services research at The Johns Hopkins Bloomberg School of Public Health. Dr. Bartman held full-time appointments on the faculty of the George Washington University School of Medicine and the University of Maryland School of Medicine, where she had a clinical practice, taught medical students and residents, and performed health services research in primary care and women's health. She joined AHRQ in 2007, after 6 years as a Medical Officer at the Health Resources and Services Administration in the Bureau of Primary Care, where she focused on improving the quality and safety of health care for underserved populations. Her current research interests include comparative effectiveness, diabetes mellitus, and quality of life measurement.
Scott Smith, R.Ph., M.S.P.H., Ph.D.
Dr. Smith is with AHRQ's Center for Outcomes and Evidence, where he is the Director of the Pharmaceutical Outcomes Research programs. Dr. Smith is a registered pharmacist with a Master's degree in Public Health from the University of Illinois and a doctorate in pharmaceutical sciences with a cognate in epidemiology from the University of Michigan in Ann Arbor. At AHRQ, he also heads the Developing Evidence to Inform Decisions about Effectiveness program, which is funded through the Medicare Modernization Act and is the Nation's largest network devoted to therapeutic effectiveness research. In addition, he is a member of the Centers for Education and Research on Therapeutics (CERTs) Steering Committee. CERTs is a national demonstration program co-administered by AHRQ and the Food and Drug Administration whose mission is to conduct research and provide education that advances the optimal use of drugs, biologicals, and medical devices. Formerly, Dr. Smith was a tenured Associate Professor at the University of North Carolina in Chapel Hill, where he maintains adjunct faculty appointments in the Schools of Pharmacy and Public Health.
Carmen Kelly, Pharm.D., R.Ph.
Dr. Kelly is a Pharmacist Officer in the Center for Outcomes and Evidence at AHRQ. Dr. Kelly obtained her Doctorate of Pharmacy from Howard University School of Pharmacy, and her Bachelor of Science in Biology from Bowie State University. Previously, Dr. Kelly worked as a pharmacy analyst at the Union Labor Life Insurance Company in Washington, DC. She has also worked as a Consultant Pharmacist with Clinical Pharmacy Associates and Health Services for Children with Special Needs. In AHRQ's Center for Outcomes and Evidence, she works with pharmacy-related projects within the Comparative Effectiveness Portfolio. Dr. Kelly's research interests include focusing on the pharmacist's role in examining health care quality and effectiveness, patient outcomes, access to care, and other new technologies related to pharmacy services. Currently, Dr. Kelly is a member of the Board of Visitors for the Howard University College of Pharmacy, Nursing and Allied Health Sciences and a member of the Editorial Advisory Board for the Journal of the American Pharmacists Association.
Internet Citation:
Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for Adults With Type 2 Diabetes. Web Conference, February 26, 2009. Agency for Healthcare Research and Quality, Rockville, MD. http://effectivehealthcare.ahrq.gov/components/webinar/04242009/files/lobby.html.