Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home
Share
Compartir

FactsFacts About DBA

Diamond Blackfan anemia (DBA) is a rare blood disorder that is also associated with birth defects or abnormal features. In DBA, the bone marrow (the center of the bone where blood cells are made) does not make enough red blood cells that carry oxygen throughout the body.   

 

Signs and Symptoms

People with DBA have symptoms common to all other types of anemia, including pale skin, sleepiness, rapid heartbeat, and heart murmurs. In some cases, there are no obvious physical signs of DBA. However, about 30 to 47% of those with DBA have birth defects or abnormal features involving the face, head, and hands (especially the thumbs). They might also have heart, kidney, urinary tract, and genital organ defects. Many children are short for their age and might start puberty later than normal.

 

Diagnosis

It is usually diagnosed during the first year of life.  Several tests can be used to tell if a person has DBA. One test a doctor can perform is called a bone marrow aspirate. This is a test in which a needle is inserted into a bone and a small amount of bone marrow fluid is taken out and studied under a microscope. Blood tests  can also be done to see if there is a genetic basis for DBA or certain chemical abnormalities linked to DBA.

 

Treatment

To treat very low red blood cell counts in people with DBA the two most common options are corticosteroid medication and blood transfusions. Bone marrow/stem cell transplantation might also be considered. Some people need no specific therapy. A qualified doctor can recommend the best treatment options.

Learn more about treatments »

 

Causes and Risk Factors

Photo: latino familySome people have a family history of the disorder. More than half of people with DBA have a known genetic cause. In many people with DBA, doctors do not know the cause.

If someone has DBA there is up to a 50% chance that each of his or her children will have DBA.

 

Who is Affected

DBA affects both boys and girls equally. It occurs in every racial and ethnic group. There are about 25 to 35 new cases of DBA each year in the United States and Canada.

 

 

 

 

 

CDC 24/7 – Saving Lives. Protecting People. Saving Money Through Prevention. Learn More About How CDC Works For You…

 

Contact Us:
  • Centers for Disease Control and Prevention

    National Center on Birth Defects and Developmental Disabilities

    Division of Blood Disorders

    1600 Clifton Road
    MS E-87
    Atlanta, GA 30333
  • 800-CDC-INFO
    (800-232-4636)
    TTY: (888) 232-6348
    New Hours of Operation
    8am-8pm ET/Monday-Friday
    Closed Holidays
  • cdcinfo@cdc.gov
USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - cdcinfo@cdc.gov
A-Z Index
  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. K
  12. L
  13. M
  14. N
  15. O
  16. P
  17. Q
  18. R
  19. S
  20. T
  21. U
  22. V
  23. W
  24. X
  25. Y
  26. Z
  27. #