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Company: Portage Bay Photonics Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: ABSTRACT: We propose to develop and validate (in phase I) detailed designs for highly scaled silicon photonic-electronic chips for applications relevant to the DOD in high-bandwidth data communication. This effort will be closely coordinated with the OPSIS (Optoelectronic Systems Integration in… more
Company: CANCER TARGETED TECHNOLOGY, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): PSMA is an important biomarker for prostate cancer prognosis and an appropriate target for therapy due to its restricted expression mainly on late-stage, androgen-independent and metastatic prostate cancer cells. Whilecurrently there is only one clinical PSMA… more
Company: Wildlife Computers, Inc. Agency/Program/Year/Phase: DOD / STTR / 2011 / 2
Abstract: Wildlife Computers presents a remote release device for use with marine mammal data-logging tags proposed with three variations to suit cetaceans and large and small pinnipeds. The device uses innovative approaches such as ElectRelease epoxy for the releasing mechanism and an Argos-based signaling… more
Company: TRIA BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): H5N1 is a highly pathogenic avian influenza virus that can cause severe disease and death in humans. H5N1 is spreading rapidly in bird populations world-wide and there is great concern that this virus will begin to transmit between people and cause a global… more
Company: Portage Bay Photonics Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: ABSTRACT: We propose to develop and validate (in phase I) detailed designs for highly scaled silicon photonic-electronic chips for applications relevant to the DOD in high-bandwidth data communication. This effort will be closely coordinated with the OPSIS (Optoelectronic Systems Integration in… more
Company: ADAPTIVE TCR CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this Phase I project is to develop a method to objectively measure immune reconstitution following hematopoietic stem cell transplantation using direct sequencing of the T-cell repertoire. This method willbe developed using data from patients treated… more
Company: Innovega Agency/Program/Year/Phase: NSF / SBIR / 2011 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project will extend the development of the contact-lens-enabled virtual reality display system demonstrated in Phase I. A key goal will be to advance the construction of the contact lenses to be ready for commercial market tests and OEM partner… more
Company: Arzeda Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project focuses on the design of a robust and low-cost enzyme immobilization system to increase the cost-competitiveness of bio-catalytic processes. The lack of a universal, sound, and affordable enzyme immobilization technique has been a large… more
Company: Arzeda Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project focuses on the development of a high-yield fermentation route for the production of levulinic acid (LA). LA is one of the best-suited C5 building blocks for bio-refinery production due to higher value, broad applications, and likely… more
Company: CANCER TARGETED TECHNOLOGY, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): PSMA is an important biomarker for prostate cancer prognosis and an appropriate target for therapy due to its restricted expression mainly on late-stage, androgen-independent and metastatic prostate cancer cells. Whilecurrently there is only one clinical PSMA… more
Company: Zwitter Tech Agency/Program/Year/Phase: NSF / STTR / 2011 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project aims to demonstrate the extraordinary performance of zwitterionic technology in protein interaction analysis. Zwitterionic polycarboxybetaine (pCB) is not only highly resistant to nonspecific protein adsorption, but also has abundant… more
Company: Hummingbird Precision Machine Inc. Agency/Program/Year/Phase: DOE / SBIR / 2011 / 1
Abstract: Researchers are currently hindered from observing dynamic gas-solid interactions in the transmission electron microscope (TEM). Yet, solid-state materials and gases interact in many important ways. The most critical technological application for these observations is catalysis, where one would like… more
Company: Hummingbird Precision Machine Inc. Agency/Program/Year/Phase: DOE / SBIR / 2011 / 2
Abstract: The primary experimental method used to determine the local internal structure of materials is that of transmission electron microscopy (TEM). If one also subjects the sample to an excursion in temperature during imaging at high resolution, one can watch the material processes involved in structural… more
Company: TISSUE REGENERATION SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): Large mandibular segmental defects resulting from tumor resection, trauma, and congenital anomalies remain one of the most difficult clinical challenges in CMF reconstruction. Autologous tissue grafts and synthetic materials are the current clinical gold standard… more
Company: Wildlife Computers, Inc. Agency/Program/Year/Phase: DOD / STTR / 2011 / 2
Abstract: Wildlife Computers presents a remote release device for use with marine mammal data-logging tags proposed with three variations to suit cetaceans and large and small pinnipeds. The device uses innovative approaches such as ElectRelease epoxy for the releasing mechanism and an Argos-based signaling… more
Company: Spi Surgical, INC Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: Background: Surgical error reduction requires addressing rapid adoption of new surgical technology. We propose development of a networked surgical assessment platform able to collect performance and outcomes data from multiple surgical platforms and sites for dynamic metrics analysis. Goal:… more
Company: Spi Surgical, INC Agency/Program/Year/Phase: DOD / STTR / 2011 / 2
Abstract: The ongoing military conflicts demonstrate the need to deploy skilled personnel equipped with advanced technology to provide medical and surgical attention as close as possible to the point of injury. A major problem is the occasional mismatch between the type of injury and the type of surgeon… more
Company: TRIA BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): H5N1 is a highly pathogenic avian influenza virus that can cause severe disease and death in humans. H5N1 is spreading rapidly in bird populations world-wide and there is great concern that this virus will begin to transmit between people and cause a global… more
Company: TISSUE REGENERATION SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The purpose of the proposal is to develop medical device coatings that bind and release therapeutic proteins, particularly growth factors. Specifically, we propose to systematically optimize and control growth factor binding and release using protocols that can… more
Company: TISSUE REGENERATION SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): Large mandibular segmental defects resulting from tumor resection, trauma, and congenital anomalies remain one of the most difficult clinical challenges in CMF reconstruction. Autologous tissue grafts and synthetic materials are the current clinical gold standard… more
Company: Beck Engineering, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2011 / 1
Abstract: NASA needs advanced power-conversion technologies to improve the efficiency and reliability of power conversion for space exploration missions. We propose to develop a Stirling generator to meet NASA needs. Our Stirling generator adapts technology we have developed for high-reliability long-life… more
Company: BEHAVIORAL TECH RESEARCH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Post-traumatic stress disorder (PTSD) is a common anxiety disorder with lifetime prevalence in the U.S. of 6.8%. Prolonged Exposure (PE), an exposure-based treatment developed by Edna Foa, Ph.D. and colleagues, is a highly efficacious treatment for PTSD. PE is… more
Company: Spi Surgical, INC Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: Background: Surgical error reduction requires addressing rapid adoption of new surgical technology. We propose development of a networked surgical assessment platform able to collect performance and outcomes data from multiple surgical platforms and sites for dynamic metrics analysis. Goal:… more
Company: Spi Surgical, INC Agency/Program/Year/Phase: DOD / STTR / 2011 / 2
Abstract: The ongoing military conflicts demonstrate the need to deploy skilled personnel equipped with advanced technology to provide medical and surgical attention as close as possible to the point of injury. A major problem is the occasional mismatch between the type of injury and the type of surgeon… more
Company: GEOSPIZA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): Next generation DNA sequencing (NGS) technologies hold great promise as tools for building a new understanding of health and disease. In the case of understanding cancer, deep sequencing provides more sensitive ways todetect the germline and somatic mutations… more
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