Act Against AIDS (AAA) is a five-year national campaign launched by the Centers for Disease Control and Prevention (CDC) and the White House to combat complacency about HIV and AIDS in the United States. Launched in 2009, Act Against AIDS focuses on raising awareness among all Americans and reducing the risk of infection among the hardest-hit populations – gay and bisexual men, African Americans, Latinos, and other communities at increased risk.

Act Against AIDS consists of several concurrent HIV prevention campaigns and uses mass media (TV, radio, newspapers, magazines, and the Internet) to deliver important HIV prevention messages. All campaigns support the comprehensive HIV prevention efforts of CDC and the National HIV/AIDS Strategy (NHAS). Act Against AIDS also supports the Act Against AIDS Leadership Initiative (AAALI), a network of national-level organizations that focus on African Americans, black men who have sex with men (MSM), and the Latino community.

For more information, read the AIDS Against AIDS original press release, the AAALI expansion announcement, and the campaign's one-year and two-year reports.