Welcome to the Vaccines and Immunizations website.
Skip directly to the search box, site navigation, or content.

Department of Health and Human Services
Centers for Disease Control and Prevention


Vaccines & Immunizations

Statistics and Surveillance:

NIS Data Analysis Methodologies

The statistical methodology for estimating vaccination coverage rates for NIS data was changed in 1998. The new methodology facilitates valid statistical analyses of NIS data that appropriately accounts for the survey's complex sampling design. Small differences exist between vaccination coverage estimates appearing in MMWRs published before 1998 and estimates published on this website.

The pre 1998 methodology is described in Zell, E.R., Ezzati-Rice, T.M., Battaglia, M.P., and Wright, R.A. (2000). National Immunization Survey: The methodology of a vaccination surveillance system. Public Health Reports, 115(1), 65-77.

The new methodology is described in Smith, P.J., Rao, J.N.K., Battaglia, M.P., Ezzati-Rice, T.M., Daniels, D., Khare, M. (2001). Compensating for provider nonresponse using response propensities to form adjustment cells: the National Immunization Survey. National Center for Health Statistics. Vital Statistics 2(133).

All estimates published on this website are calculated using this new methodology.

External Web Site Policy This symbol means you are leaving the CDC.gov Web site. For more information, please see CDC's Exit Notification and Disclaimer policy.

File Formats: All viewers, players, and plug-ins used on this site can be downloaded from the file formats page. (For example: Adobe Acrobat Reader for pdf files, Windows Media Player for audio and video files, PowerPoint Viewer for presentation slides, etc.)

This page last modified on December 21, 2001
Content last reviewed on December 21, 2001
Content Source: National Center for Immunization and Respiratory Diseases

Quick Links

Safer Healthier People

Centers for Disease Control and Prevention 1600 Clifton Rd, Atlanta, GA 30333, U.S.A
Public Inquiries: 1-800-CDC-INFO (232-4636); 1-888-232-6348 (TTY)

Vaccines and Immunizations