The search textbox has an autosuggest feature. When you enter three or more characters,
a list of up to 10 suggestions will popup under the textbox. Use the arrow keys
to move through the suggestions. To select a suggestion, hit the enter key. Using
the escape key closes the listbox and puts you back at the textbox. The radio buttons
allow you to toggle between having all search items start with or contain the text
you entered in the search box.
L-leucovorin
The active l-isomer of the racemic mixture of the 5-formyl derivative of tetrahydrofolic acid. Metabolically active, l-leucovorin, also known levoleucovorin, does not require bioactivation by dihydrofolate reductase, an enzyme inhibited by folic acid antagonists. This agent may enhance the effects of fluoropyrimidines by stabilizing their binding to the enzyme thymidylate synthase. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | Calcium levoleucovorin Levofolinate Levofolinate calcium Levofolinic acid Levoleucovorin | ||
US brand name: | Isovorin | ||
Foreign brand name: | Elvorine, Isovorin, Levofolene, Levorin | ||
Abbreviation: | L-CF | ||
Code name: | CL-307,782 | ||
Chemical structure: | L-5-Formyltetrahydrofolate | ||