Day 1 - October 9, 2012 |
Introduction and Background |
8:30 a.m. |
Introduction—Opening Remarks Christine Hunter, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Remarks from National Institute of Mental Health (NIMH): Setting the Stage Tom Insel, Director, NIMH |
8:45 a.m. |
Broad Overview of the Meeting and the State-of- the-Science:
Incidence, Prevalence, and Bi-directionality of the Diabetes and Depression Association Sherita Golden
Public Health Impact of Co-morbid Diabetes and Depression Norman Sartorius |
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Session 1: Mechanisms Linking Diabetes and Depression Session Chairs: Irwin Lucki, Ph.D., and Sherita Golden, M.D., M.H.S |
9:15 a.m. |
Mechanisms Linking Diabetes and Depression: Session Introduction Irwin Lucki |
9:20 a.m. |
Overview of Potential Mechanisms for the Link Between Diabetes and Depression Khalida Ismail |
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NEUROENDOCRINE FACTORS
Hypothalamic-Pituitary-Adrenal (HPA) Axis |
9:40 a.m. |
The Role of the HPA Axis in Neuroplasticity as a Link to Depression and Cognitive Co-morbidities in Animal Models of Diabetes Alexis Stranahan |
10:00 a.m. |
Evidence of HPA Axis Dysfunction in Depression and Diabetes in Clinical and Population-based Studies Sherita Golden |
10:15 a.m. |
Depression and Risk of Cognitive Decline in Diabetes—Evidence From Human Studies Rachel Whitmer |
10:30 a.m. |
Question-and-Answer Session Moderator: Irwin Lucki |
10:50 a.m. |
Remarks from NIDDK: Setting the Stage Griffin Rodgers, Director, NIDDK |
11:00 a.m. |
BREAK
Circadian Rhythms and Sleep Disturbance |
11:20 a.m. |
The Role of Circadian Rhythms in Regulating Metabolism—Basic Science Mechanisms Orefeu Buxton |
11:35 a.m. |
Effects of Sleep Disturbances on Metabolic Function, Diabetes Risk, and Depression David Ehrmann |
11:50 a.m. |
Question-and-Answer Session Moderator: Irwin Lucki |
12:10 p.m. |
LUNCH ̶ Boxed Lunch With Advance Purchase
Inflammation |
1:10 p.m. |
The Role of Inflammation and Immunological Challenge as a Bridge Between Depression and Diabetes—Lessons From Animal Models Robert Dantzer |
1:25 p.m. |
Evidence of Inflammation in the Pathophysiology of Depression and Diabetes in Human Studies Charles Raison |
1:40 p.m. |
Question-and-Answer Session Moderator: Sherita Golden |
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BEHAVIORAL, PSYCHOSOCIAL, AND ENVIRONMENTAL FACTORS |
1:55 p.m. |
Contextual Factors in Diabetes and Depression Tiffany Webb-Gary |
2:10 p.m. |
Diabetes Distress Versus Depression: Implications for Glycemic Control Mary de Groot |
2:25 p.m. |
Adherence to Diabetes Self-care Behaviors in Depression Jeff Gonzalez |
2:40 p.m. |
Depression in Children with Diabetes Maria Kovacs |
2:55 p.m. |
Question-and-Answer Session Moderator: Peter Muehrer |
3:15 p.m. |
BREAK
TREATMENT FACTORS |
3:35 p.m. |
Antidepressant Treatments in Animal Models of Diabetes Irwin Lucki |
3:50 p.m. |
Association of Antidepressant and Antipsychotic Treatments With Obesity and Incident Diabetes in Population-based Studies Richard Holt |
4:05 p.m. |
Question-and-Answer Session Moderator: Sherita Golden |
4:25 p.m. |
Panel Discussion: Implications for Clinical and Behavioral Research? What Are the Crucial Unanswered Research Questions? Alan Jacobson and Robert Ratner
Question-and-Answer Session Moderator: Christine Hunter |
5:05 p.m. |
Wrap-up and Logistics for Day 2 Christine Hunter |
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Day 2 - October 10, 2012 |
8:00 a.m. |
Welcome Back and Orientation to the Day’s Schedule Peter Muehrer |
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Session 2: Treatment Session Chair: Wayne Katon, M.D., and Mary de Groot, Ph.D. |
8:10 a.m. |
Session Introduction Wayne Katon |
8:25 a.m. |
Are Evidenced-based Depression Treatments Effective in Treating Co-morbid Depression in Patients With Diabetes, and Do These Treatments Improve Diabetes Disease Control? Christina van der Feltz-Cornelis |
8:45 a.m. |
Question-and-Answer Session Moderator: Mary de Groot |
9:00 a.m. |
Improving Depression Outcomes in Large Populations of Patients With Diabetes: Collaborative Depression Care Paul Ciechanowski |
9:20 a.m. |
Question-and-Answer Session Moderator: Wayne Katon |
9:35 a.m. |
Multi-condition Collaborative Care for Both Depression and Diabetes Wayne Katon |
9:55 a.m. |
Question-and-Answer Session Moderator: Mary de Groot |
10:10 a.m. |
BREAK |
10:30 a.m. |
Effect of Improving Diabetes Disease Control in Large Populations of Patients With Diabetes on Psychological Distress and Well-being Patrick O’Connor |
10:50 a.m. |
Question-and-Answer Session Moderator: Wayne Katon |
11:05 a.m. |
Improving Depressive Symptoms and HbA1C Outcomes in Patients With Type I Diabetes Alan Jacobson |
11:25 a.m. |
Question-and-Answer Session Moderator: Mary de Groot |
11:40 a.m. |
Panel Discussion: What are the Crucial Unanswered Research Questions? John Hayes and Arie Nouwen |
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Question-and-Answer Session Moderator: Peter Muehrer |
12:15 p.m. |
LUNCH ̶ Boxed Lunch With Advance Purchase |
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Session 3: Prevention and Public Health Session Chairs: Richard Holt, Ph.D., F.R.C.P., and Norman Sartorius, M.D., Ph.D. |
1:15 p.m. |
Session Introduction Richard Holt |
1:30 p.m. |
Prevention of Diabetes in Those With Depression: Findings From the Major Diabetes Prevention Trials David Marrero |
1:50 p.m. |
Question-and-Answer Session Moderator: Richard Holt |
2:05 p.m. |
Prevention of Depression in Those With Diabetes Edwin Fisher |
2:25 p.m. |
Question-and-Answer Session Moderator: Richard Holt |
2:40 p.m. |
BREAK |
3:00 p.m. |
Roundtable Chair: Norman Sartorius
Dissemination, Implementation, and Public Health Panel: The Evidence and Research Needs in Health Policy, Health Education, and Health Economics Related to the Prevention and Management of Co-morbid Diabetes and Depression Panel: Santosh Chaturvedi, Leonard Egede, Edwin Fisher,Wayne Katon, David McDaid, Brian Oldenberg, François Pouwer, Robert Ratner, and Richard Roberts |
4:30 p.m. |
Concluding Remarks Sherita Gordon and Norman Sartorius |