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Company: InnovaPrep LLC Agency/Program/Year/Phase: DHS / SBIR / 2012 / 2
Abstract: Detection of bioaerosols is a cornerstone in the protection of our nation from bioterrorist and pandemic events. Rapid bioaerosol detection systems
have advanced dramatically in recent years, but the lack of integratable automated sample preparation for these systems remains a major deficiency… more
Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Our long term goal is to widespread the use of PPF technology for promoting effective production of drug-encapsulating microparticles with uniform size and physical characteristics that can be leveraged to release a specific drug at controlled rates over… more
Company: VASCULOX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Organ transplantation is one of the great success stories of modern medicine. However, the supply of suitable organs lags far behind the need and many patients die while waitlisted for organs. While there have been manyrecent strides in organ procurement,… more
Company: DNA Polymerase Technology, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2011 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project proposes the development of novel enzymes (DNA polymerases) and other improvements for rapid detection of food-borne pathogens by DNA detection and amplification (PCR). PCR is a very fast and accurate method of pathogen detection,… more
Company: C2N DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): This grant will seek to develop a methodology that will allow us to test whether a promising new class of drugs for Alzheimer's disease is having the desired effect in the human brain. This methodology will allow pharmaceutical companies to make informed… more
Company: Innovative Technology Applications Co., L. L. C. Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: ABSTRACT: Flight tests of hypersonic maneuvering vehicles are a challenging but necessary endeavor. While ground tests and numerical simulations can provide important guidance regarding vehicle performance, they are both limited in their reach. Likewise surface-based measurements during flight… more
Company: C2N DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 2
Abstract: DESCRIPTION (provided by applicant): This grant will seek to develop a methodology that will allow us to test whether a promising new class of drugs for Alzheimer's disease is having the desired effect in the human brain. This methodology will allow pharmaceutical companies to make informed… more
Company: NANOVA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Improved long-term biocompatibility of coronary stents by plasma coating process Abstract Drug-eluting stents (DES) have been widely used to treat patients of cardiac disease due to their better ability to control restenosis than bare metal stents (BMS). However,… more
Company: Innovative Technology Applications Co., L. L. C. Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: ABSTRACT: Flight tests of hypersonic maneuvering vehicles are a challenging but necessary endeavor. While ground tests and numerical simulations can provide important guidance regarding vehicle performance, they are both limited in their reach. Likewise surface-based measurements during flight… more
Company: IST-ROLLA Agency/Program/Year/Phase: NASA / SBIR / 2011 / 2
Abstract: IST-Rolla developed two nonlinear filters for spacecraft orbit determination during the Phase I contract. The theta-D filter and the cost based filter, CBF, were developed and used in various orbit determination scenarios. The scenarios were application to low Earth orbit, range only, and range and… more
Company: MEDIOMICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: Glycosylation changes are a universal feature of malignant transformation and tumor progression. Changes in expression levels of certain glycoproteins and altered glycosylation patterns have been detected in most of the major human cancer types and at different stages of tumor progression. The… more
Company: MEDIOMICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: According to the American Cancer Society, 192,370 women in the United States will be diagnosed with invasive breast cancer in 2010, leading to 40,170 deaths. Most women with breast cancer undergo surgery to remove the cancerous tissue and then receive additional treatment. Adjuvant therapy does not… more
Company: Product Innovation and Engineering, L.L.C. Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project will develop a Multi-Axis Repair System (MARS), which is an automated precision alignment and repair planner and driver. MARS will make repair processes much more cost-effective and robust. Insufficient automation in current repair… more
Company: QM Power, Inc Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project evaluates a completely new low cost/high efficiency generator system called Q-Gen? Portable for use in portable recharging devices. The Q-Gen? Portable will recharge handheld electronic devices (laptops, cell phones etc) without… more
Company: QM Power, Inc Agency/Program/Year/Phase: NASA / SBIR / 2011 / 2
Abstract: QM Power will build and empirically test Space and Cryogenic qualified preproduction Parallel Magnetic Circuit [PMC] 1-5 HP motor/actuators with electronic controllers. These preproduction prototypes will demonstrate lower operating power requirements for cryogenic motor/actuator components used in… more
Company: QM Power, Inc Agency/Program/Year/Phase: DOE / SBIR / 2011 / 1
Abstract: Refrigeration and air conditioning in buildings, industry, and transportation account for approximately 10 quads of U.S. primary energy consumption. Motors power the equipment and control the environment in advanced cooling applications and thus their energy consumption represents a significant part… more
Company: QM Power, Inc Agency/Program/Year/Phase: DOE / SBIR / 2011 / 1
Abstract: Today, conventional hydropower generation accounts for 75% of the United States renewable energy generation (over 270,000 GWH) despite utilizing less than 20% of the usable hydropower available for development. Recent studies indicate that advances in lower cost higher performing generator… more
Company: InnovaPrep LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): A rapid method for concentrating bacteria from real apple juice and spinach wash water into a small volume, which is easily analyzed by advanced detectors, will enable rapid detection of small numbers of bacteria and provide for improved consumer safety and… more
Company: InnovaPrep LLC Agency/Program/Year/Phase: DHS / SBIR / 2011 / 1
Abstract: Detection of bioaerosols is a cornerstone in the protection of our nation from bioterrorist events. Rapid bioaerosol detection systems
have advanced dramatically in recent years, but the lack of integratable automated sample preparation for these systems remains a
major deficiency. Three significant… more
Company: Innovative Technology Applications Co. Agency/Program/Year/Phase: NASA / SBIR / 2011 / 1
Abstract: Shock-wave/boundary-layer interactions (SWBLI) pose challenges to aeronautical engineers because they create regions of adverse pressure gradients as a result of the discontinuous change in conditions across the shock. This shock-induced pressure gradient is a common factor for both flow separation… more
Company: Butrolix, LLC Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1
Abstract: This Small Business Innovation Research Phase I project will develop a process to increase the productivity and yield of biobutanol from cultures of solvent-forming Clostridium by treating cultures with recently discovered Clostridium quorum-sensing molecules. The biobutanol fermentation can be… more
Company: KENTUCKY PHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The purpose of this SBIR project is to develop a new dual-modality inflammation imaging technology to early detect Uveitis, an ocular inflammation-related disorder. This technology, based on nanocomposites (NCs) that function as dual-modality fluorescent and… more
Company: SARMONT, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Nitric oxide (NO) has been shown to have powerful, broad-spectrum antimicrobial activity as well as benefits in wound healing when properly administered [1-3]. The combination of these two attributes makes development of a non-systemic NO delivery approach… more
Company: CARDIALEN, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Atrial fibrillation (AF) is the most prevalent clinical arrhythmia in clinical practice and a major contributor to morbidity and mortality. A recent study estimated that the number of Americans afflicted by AF will increase from the current range of 2.2 to 5.6… more
Company: EXOCYTRONICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Cells secrete hormones and neurotransmitter via exocytosis. Understanding how exocytosis is regulated and how pharmaceuticals and toxins inhibit exocytosis is of broad medical significance. The overall goal of this SBIRproject is to use microfabrication… more
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