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methylmercaptopurine riboside
A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym: | methylthioinosine | ||
Abbreviations: | 6-MMPR MMPR | ||
Code names: | NCI-C04784 SQ 21977 | ||
Chemical structures: | 6-(methylmercapto)purine ribonucleoside 6-(methylthio) inosine 6-(methylthio)purine ribonucleoside 6-(methylthio)purine riboside 6-methyl MP riboside 6-methylmercaptopurine riboside 6-methylthioinosine 9H-purine, 6-(methylthio)-9beta-D-ribofuranosyl 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl- (8CI 9CI) 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl-, dihydrate beta-D-ribosyl-6-methylthiopurine purine-6-thiol,6-methyl-9-ribofuranosyl | ||