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![](https://webarchive.library.unt.edu/web/20120926074019im_/http://www.cancer.gov/images/spacer.gif)
adenovirus encoding human aquaporin-1
A replication-deficient, recombinant adenovirus encoding human aquaporin-1 with potential membrane water channel activity. Upon transfection of salivary glands, adenovirus encoding human aquaporin-1 (AdhAQP1) directs human aquaporin-1 (hAQP1) expression in the apical and basolateral plasma membranes of salivary secretory cells, which may result in increased saliva production. hAQP1, a water channel protein, is one of several highly conserved water channel proteins that mediate water permeability in cells of water-transporting tissues. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
![](https://webarchive.library.unt.edu/web/20120926074019im_/http://www.cancer.gov/images/spacer.gif)
Abbreviation: | ![]() | AdhAQP1 | |
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