Baibakov, B, Boggs, NA, Yauger, B, Baibakov, G and Dean, J Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice. J. Cell Biol., in press.
Burkart, AD, Xiong, B, Baibakov, B, Jimenez-Movilla, M and Dean, J Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy. J. Cell Biol. (197): 37-44, 2012. [Full Text/Abstract]
Avella, MA and Dean, J Fertilization with acrosome-reacted mouse sperm: Implications for the site of exocytosis.Proc. Natl. Acad. Sci. (USA) , (108): 19843-19844, 2011. [Full Text/Abstract]
Jimenez-Movilla, M and Dean, J ZP2 and ZP3 cytoplasmic tails prevent premature interactions and ensure incorporation into the zona pellucida. J Cell Sci, (124): 940-950, 2011. [Full Text/Abstract]
Yauger, B, Boggs, N and Dean, J Human ZP4 is not sufficient for taxon-specific sperm recognition of the zona pellucida in transgenic mice. Reproduction, (141): 313-319, 2011. [Full Text/Abstract]
Gahlay, G, Gauthier, L, Baibakov, B, Epifano, O and Dean, J Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein. Science , (329): 216-219, 2010. [Full Text/Abstract]
Hu, W, Gauthier, L, Baibakov, B, Jimenez-Movilla, M and Dean, J FIGLA, a bHLH transcription factor, balances sexually dimorphic gene expression in post-natal oocytes. Mol Cell Biol , (30): 3661-3671, 2010. [Full Text/Abstract]
Li, L, Zheng, P and Dean, J Maternal control of early mouse development. Development , (137): 859-870, 2010. [Full Text/Abstract]
Zheng, P and Dean, J Role of Filia, a maternal effect gene in maintaining euploidy during cleavage stage mouse embryogenesis. Proc Natl Acad Sci (USA), ( 106): 7433-7478, 2009. [Full Text/Abstract]
Li L, Baibakov, B and Dean J A subcortical maternal complex essential for pre-implantation mouse embryogenesis Dev Cell (15): 416-425, 2008. [Full Text/Abstract]
Ohsugi, M, Zheng, P, Baibakov, B, Li L and Dean J Maternally derived FILIA/MATER complex localizes asymmetrically in cleavage stage mouse embryos Development (135): 259-69, 2008. [Full Text/Abstract]
Zheng P, Dean J Oocyte-specific genes affect folliculogenesis, fertilization, and early development. Semin Reprod Med (25): 243-51, 2007. [Full Text/Abstract]
Joshi S, Davies H, Sims LP, Levy SE, Dean J Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor. BMC Dev Biol (7): 67, 2007. [Full Text/Abstract]
Baibakov B, Gauthier L, Talbot P, Rankin TL, Dean J Sperm binding to the zona pellucida is not sufficient to induce acrosome exocytosis. Development (134): 933-43, 2007. [Full Text/Abstract]
Hoodbhoy T, Aviles M, Baibakov B, Epifano O, Jimenez-Movilla M, Gauthier L, Dean J ZP2 and ZP3 traffic independently within oocytes prior to assembly into the extracellular zona pellucida. Mol Cell Biol (26): 7991-8, 2006. [Full Text/Abstract]
Hoodbhoy T, Joshi S, Boja ES, Williams SA, Stanley P, Dean J Human sperm do not bind to rat zonae pellucidae despite the presence of four homologous glycoproteins. J Biol Chem (280): 12721-31, 2005. [Full Text/Abstract]
Zhao M, Boja ES, Hoodbhoy T, Nawrocki J, Kaufman JB, Kresge N, Ghirlando R, Shiloach J, Pannell L, Levine RL, Fales HM, Dean J Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells. Biochemistry (43): 12090-104, 2004. [Full Text/Abstract]
Dean J Reassessing the molecular biology of sperm-egg recognition with mouse genetics. Bioessays (26): 29-38, 2004. [Full Text/Abstract]
Rankin TL Coleman JS Epifano O Hoodbhoy T Turner SG Castle PE Lee E Gore-Langton R Dean J Fertility and taxon-specific sperm binding persist after replacement of mouse sperm receptors with human homologs. Dev Cell (5): 33-43, 2003. [Full Text/Abstract]
Zhao M Gold L Dorward H Liang LF Hoodbhoy T Boja E Fales HM Dean J Mutation of a conserved hydrophobic patch prevents incorporation of ZP3 into the zona pellucida surrounding mouse eggs. Mol Cell Biol (23): 8982-91, 2003. [Full Text/Abstract]
Boja ES Hoodbhoy T Fales HM Dean J Structural characterization of native mouse zona pellucida proteins using mass spectrometry. J Biol Chem (278): 34189-202, 2003. [Full Text/Abstract]
Zhao M Gold L Ginsberg AM Liang LF Dean J Conserved furin cleavage site not essential for secretion and integration of ZP3 into the extracellular egg coat of transgenic mice. Mol Cell Biol (22): 3111-20, 2002. [Full Text/Abstract]
Epifano O Dean J Genetic control of early folliculogenesis in mice. Trends Endocrinol Metab (13): 169-73, 2002. [Full Text/Abstract]
Rankin TL O''Brien M Lee E Wigglesworth K Eppig J Dean J Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development. Development (128): 1119-26, 2001. [Full Text/Abstract]
Takasaki N Rankin T Dean J Normal gonadal development in mice lacking GPBOX, a homeobox protein expressed in germ cells at the onset of sexual dimorphism. Mol Cell Biol (21): 8197-202, 2001. [Full Text/Abstract]
de Vries WN Binns LT Fancher KS Dean J Moore R Kemler R Knowles BB Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes. Genesis (26): 110-2, 2000. [Full Text/Abstract]
Soyal SM Amleh A Dean J FIGalpha, a germ cell-specific transcription factor required for ovarian follicle formation. Development (127): 4645-54, 2000. [Full Text/Abstract]
Takasaki N McIsaac R Dean J Gpbox (Psx2), a homeobox gene preferentially expressed in female germ cells at the onset of sexual dimorphism in mice. Dev Biol (223): 181-93, 2000. [Full Text/Abstract]
Tong ZB Nelson LM Dean J Mater encodes a maternal protein in mice with a leucine-rich repeat domain homologous to porcine ribonuclease inhibitor. Mamm Genome (11): 281-7, 2000. [Full Text/Abstract]
Tong ZB Gold L Pfeifer KE Dorward H Lee E Bondy CA Dean J Nelson LM Mater, a maternal effect gene required for early embryonic development in mice. Nat Genet (26): 267-8, 2000. [Full Text/Abstract]