1. Hook-Barnard I, Johnson XB, Hinton DM Escherichia coli RNA polymerase recognition of a sigma70-dependent promoter requiring a -35 DNA element and an extended -10 TGn motif. J Bacteriol (188): 8352-9, 2006. [Full Text/Abstract]
2. Baxter K, Lee J, Minakhin L, Severinov K, Hinton DM Mutational analysis of sigma70 region 4 needed for appropriation by the bacteriophage T4 transcription factors AsiA and MotA. J Mol Biol (363): 931-44, 2006. [Full Text/Abstract]
3. Hinton DM, Vuthoori S, Mulamba R The bacteriophage T4 inhibitor and coactivator AsiA inhibits Escherichia coli RNA Polymerase more rapidly in the absence of sigma70 region 1.1: evidence that region 1.1 stabilizes the interaction between sigma70 and core. J Bacteriol (188): 1279-85, 2006. [Full Text/Abstract]
4. Hinton DM Molecular gymnastics: distortion of an RNA polymerase sigma factor. Trends Microbiol (13): 140-3, 2005. [Full Text/Abstract]
5. Hinton DM, Pande S, Wais N, Johnson XB, Vuthoori M, Makela A, Hook-Barnard I Transcriptional takeover by sigma appropriation: remodelling of the sigma70 subunit of Escherichia coli RNA polymerase by the bacteriophage T4 activator MotA and co-activator AsiA. Microbiology (151): 1729-40, 2005. [Full Text/Abstract]
6. Pineda, M., Gregory, B. D., Szczypinski, B. Baxter, K. R., Hochschild,A., Miller, E. S., and Hinton, D. M. A Family of Anti-s70 Proteins in T4-type Phages and Bacteria That Are Similar to AsiA, a TranscriptionInhibitor and Co-activator of Bacteriophage T4. J. Mol. Biol. , 2004. [In Press]
7. Pal D, Vuthoori M, Pande S, Wheeler D, Hinton DM Analysis of regions within the bacteriophage T4 AsiA protein involved in its binding to the sigma70 subunit of E. coli RNA polymerase and its role as a transcriptional inhibitor and co-activator. J Mol Biol (325): 827-41, 2003. [Full Text/Abstract]
8. Pande S, Makela A, Dove SL, Nickels BE, Hochschild A, Hinton DM The bacteriophage T4 transcription activator MotA interacts with the far-C-terminal region of the sigma70 subunit of Escherichia coli RNA polymerase. J Bacteriol (184): 3957-64, 2002. [Full Text/Abstract]
9. Vuthoori S, Bowers CW, McCracken A, Dombroski AJ, Hinton DM Domain 1.1 of the sigma(70) subunit of Escherichia coli RNA polymerase modulates the formation of stable polymerase/promoter complexes. J Mol Biol (309): 561-72, 2001. [Full Text/Abstract]
10. Hinton DM, Vuthoori S Efficient inhibition of Escherichia coli RNA polymerase by the bacteriophage T4 AsiA protein requires that AsiA binds first to free sigma70. J Mol Biol (304): 731-9, 2000. [Full Text/Abstract]
11. Sharma M, Marshall P, Hinton DM Binding of the bacteriophage T4 transcriptional activator, MotA, to T4 middle promoter DNA: evidence for both major and minor groove contacts. J Mol Biol (290): 905-15, 1999. [Full Text/Abstract]
12. Marshall P, Sharma M, Hinton DM The bacteriophage T4 transcriptional activator MotA accepts various base-pair changes within its binding sequence. J Mol Biol (285): 931-44, 1999. [Full Text/Abstract]
13. Gerber JS Hinton DM An N-terminal mutation in the bacteriophage T4 motA gene yields a protein that binds DNA but is defective for activation of transcription. J Bacteriol (178): 6133-9, 1996. [Full Text/Abstract]
14. Hinton DM March-Amegadzie R Gerber JS Sharma M Bacteriophage T4 middle transcription system: T4-modified RNA polymerase; AsiA, a sigma 70 binding protein; and transcriptional activator MotA. Methods Enzymol (274): 43-57, 1996. [Full Text/Abstract]
15. Hinton DM March-Amegadzie R Gerber JS Sharma M Characterization of pre-transcription complexes made at a bacteriophage T4 middle promoter: involvement of the T4 MotA activator and the T4 AsiA protein, a sigma 70 binding protein, in the formation of the open complex. J Mol Biol (256): 235-48, 1996. [Full Text/Abstract]
16. March-Amegadzie R Hinton DM The bacteriophage T4 middle promoter PuvsX: analysis of regions important for binding of the T4 transcriptional activator MotA and for activation of transcription. Mol Microbiol (15): 649-60, 1995. [Full Text/Abstract]